Clinical Trial E5103

carolynf · June 2008

Hi Ladies,

Desi, my onc. either looks them up or talks to the trial guru's. I had a long talk w/him because most Dr's will tell you no due to the supps not being regulated by the FDA. In Europe, they use them widely. At Beth Israel Hosp in Boston they use standard treatment w/holistic medicine. I got that information from a women whose daughter was diagnosed at age 2mo and she took all the stuff that i wrote and standard treatment and has been cancer free for 10 yrs. She's 12 yrs old right now. It all depends on your onc. and their training and the way they look at alternative meds. My onc. even recommended accupunture, reiki, and massage. I had the same treatment as you and am still in the trial. Thanks for the tea tree oil. I might try that one. I have no idea where you would find Emu oil and if you do it would be very expensive. I would also ask your dr for a script of Lorazapam/ativan to help you sleep at night. I started off taking 1 pill a night and it definitely helps you function the next day because you got a good nights sleep. I have tried to wean myself but i was up most of the night and the dr said to stay on til i am done my treatments and then we can wean off.

Teresa, I agree w/Desi and go to vegas. If you are only getting the avastin, I would definitely do it before you head. It does not have those se's as the other drugs. I am glad to hear your hair is growing. The top of mine is pretty long considering no hair before. It actually over my ears to but i would like it a little longer so i can do a semi permanent. I had my daughter tell me that my hair now matches my husbands!! The truth is it does. Took today off from work due to being extremely tired. Its only the 2nd wk of rads but I was falling asleep on the couch watching the news. I figured, what the heck, i am tired so go back to bed and call work to let them know. I tried falling asleep again and the puppy was moving around too much so we went outside. I put my bsuit on and went to the pool. Lexi (my dog) and me went for a swim. She will not go off the diving board but does walk in via the steps, very gently and follows me around. Just have to be careful about the liner! Well, I am going to try and nap a bit. Lexi is snoring so she will be asleep for awhile.

Keep smiling Laughing

Carolyn

brena · June 2008

Hi everyone,

Not sure where to start but am sure to write a book by the time I am done.

Teresa,

Take the shot then go to Vegas, who are you traveling with? Have you been there before? Wish you lots of luck and much money! Nice to hear the Avastin shot is not beating you up. Did the Keflex help with the infection in the finger nails, I may try it if mine get infected again. I have lost another 1.5 finger nails with two more giving pain in the nail bed and loose nails. Bought two more boxes of band-aids of various sizes and am now ready for the rest of them.

Much happiness with the new house and may all your transactions go smooth. Is the new house in the same town you currently reside in?

Did you ever determine your trial sequence number? I believe the number they gave you had too many digits.

take care,

brena · June 2008

Carolyn,

You make me tired just reading your busy schedule I can't believe you still need sleeping aids. I hope everyone at your home is healthy and ready for summer. Will the kids be involved in soccer or all stars over the summer?

Tomorrow I get to go to rads verification to ensure their torture from last week was sufficient, will also find out total rads that are required. Heck they might even start the rad session immediately after the torture verification. I am so EXCITED Yell definately a sleeping pill night. Next week will probably be my last week at work until the end of summer while I do rads. My reward to myself for following through with the daily frying.

Will tan before I go to rads...am using sunblock 30 when I go for my bike ride and still getting a heck of a tan. Probably the only good SE from the Taxel.

Thursday will visit the Onc to review test results and hopefully get registered for the next trial, I think I have completed all requirements.

Body hair is starting to grow, all hair except the center of my head. If it doesn't show some action by this weekend again I will need to trim the sides and back so all are the same length. Picture a skunk with the white stripe, that white stripe is where my hair is NOT growing. Yes, I will be patient.

What are you going to do for a whole week the kids are at camp?

talk soon,

brena · June 2008

Carol,

Carolyn and me had a lumpectomy which requires radiation therapy. Good luck with your first chemo session on Thursday, it is usually a long session. Let us know how your sessions goes. Again, let us know if we can make your journey a little smoother or more informative.

How long have you lived in Chicago?

take care,

brena · June 2008

Desi,

How are you making out with the cough, what did the doc recommend?

I read you had a lumpectomy so you will also be going through radiation after your chemo, is this correct?

If you don't mind what is your age; so far we have (3) at age 46 and (1) at 42. Have a good session this Friday at your next round of chemo. Are you doing your sessions at Dr's office or in a hospital?

have a good week,

brena · June 2008

Desi,

How are you making out with the cough, what did the doc recommend?

I read you had a lumpectomy so you will also be going through radiation after your chemo, is this correct?

If you don't mind what is your age; so far we have (3) at age 46 and (1) at 42. Have a good session this Friday at your next round of chemo. Are you doing your sessions at Dr's office or in a hospital?

have a good week,

S3K5 · June 2008

Hi Brena,

Thanks for asking. My cough is okay during daytime and horrible at nights. The doctors are trying different antihistamines - nothing is working. The chest x-ray was clear. No bronchial infection.

I had a lumpectomy and will have radiation after chemo (4 doses of dd AC and then weekly Taxol for 12 weeks). My chemo treatment is in the doctor's office - actually this group is located within the hospital building but is a private practice. Where are you getting your treatments?

By the way - I am 49.

Take care,

Desi.

cjw · June 2008

Brena

Just had first session today. Was at the hospital all day--drs appts, labs, then the chemo (some waiting around time). The next ones should go more quickly. So far, feel fine, although I suspect that will change in next couple days. Am taking all the anti-nausea meds. I think I dont get radiation because I had a mastectomy (even though the tumor was small, there was some DCIS as well, so they recommended mastectomy.) I am surprised that all the node negative ladies are having chemo--I thought if the nodes were clear, you were home free other than radiation (at least that's what it seems like a lot of women here do). I was bummed to find it in the lymph nodes with a pretty small tumor.

I've been in Chicago most of my life, other than college and a 5 year stint in London.

Carol

brena · June 2008

Desi,

Sorry to hear you still have the cough but glad your test results came back negative. Keep trying different remedies until you find one that works, is the cough listed as a symptom in the packet for either A/C?

I received my chemo and taxel shot in the Oncologist office located in Mickleton NJ, very nice place. This office is located about 35 minutes from my home.

I started my rads today and I travel 30 minutes the opposite direction, located SJHC in Cumberland County NJ.

May your future shots be as gentle as the first! Keep us updated on your progress.

Are you working outside the home while going through chemo and radiation?

smiles,

brena

S3K5 · June 2008

Brena,

I am so jealous that you are already done with chemo! I finished my 2nd round of A/C+Avastin/placebo yesterday. The port was not working - different nurses tried poking, heparin rinse, etc. Finally they decided to do it by left arm vein. I was given 0.5 mg ativan - so that helped me with the pain and my cough subsided a little bit. The onco thinks it is allergies. Gave me strong antihistamine+Tussin with codeine - helps me sleep! With my 2nd round SE's aren't too bad (a little nausea and dizziness today) but tolerating well. Due to my severe cough I decided to go on STD since last week. In eight weeks, I will have only Taxol +Avastin (i.e. if I am in Arm B or C). By then,hopefully, the se's will be minimum and I can return to work. Enough about me!

How was your radiation session? What kind of SEs do you have? Is it bearable? Since you had lumpectomy (like me), will you be getting 31-35 days of daily radiation? Were you able to drive after the radiation session?

Do you work outside of home? I work in a pharma company.

Good luck.

Desi.

brena · June 2008

Desi,

Good to hear from you and we share the same state, not sure if that is good or not but I am glad you joined the trial and our group.

My allergies were horrible during the entire chemo session and I took everything over the counter + scripts and nothing worked so I stopped taking it all. I did not know my stuffiness, sneezing, runny nose etc. was allergies at the time, thought it was the drugs. The chemo drugs challenged my immune system, minimal problems with allergies right now. Hang in there and I hope your allergies show improvement quicker than mine.

The A/C and Taxel effect each of us different. I was not able to decrease some of their SE's with alternate drugs not even antibiotics.

I worked 3 of the 5 days during chemo+taxel and some days it was very tough but I left work a little earlier when needed. I wanted to bank enough work days so I could take off during most of radiation so next week is my last work week until Sept. 2nd. I feel like I have not slept since the start of chemo last Dec. I am getting 2-3hrs without sleep aid and 4-5hrs with sleep aid, no naps or rest period during the day. The steroids were a big contributor to this especially when getting weekly doses of taxel. I believe all the drugs are out of my system so I am not sure why I am still having problems sleeping, when I get to the zombie zone I take the sleeping aid. It took 3 different scripts before I found a sleep aid that gave 4-5hrs. Again, the chemo drugs just ruled my body.

My goal is to sleep the entire time I am out for STD except for appointments. I think I have adjusted and function good for the lack of sleep but am hoping to return to a normal sleep some day in the near future w/out sleep aids.

Teresa and Carolyn are not having to many difficulties with the Avastin, some SE's but they said they are manageable.

I did well with the taxel up to about the fourth dose and then developed an unusual rash on the wrist/arms as did Teresa but not Carolyn (see old posts.) I am now having more SE's from Taxel than I did while taking the Taxel, no neuropathy thank goodness. I have now lost 2 toenails and 3 fingernails (all infected before falling off.) If history repeats itself there are 3 more fingernails that will depart very soon. Good news, there are new nails underneath that are making an attempt to sprout. They better be beautiful!

Summary, two biggest SE was lack of sleep and that damn taxel; otherwise, I had pretty smooth sailing. Shortly after the 2nd round of A/C I felt the worse, thought the Onc was trying to kill me along with the cancer cells. I did whine about some minor issues; allergies, nose bleed etc.

I took up an aggressive exercise program (for me) which I believe helped with the minimal SE's and I actually lost weight through this entire chemo regimen.

Most important is would I do it again and yes I would, the trial was my choice which added the taxel to my cocktail. My nails will grow back and I will develop a normal sleep pattern some day and I try to remember there are other woman with more severe and everlasting problems.

My radiation setup (torture) and verification of the torture just literally sucked! No more to be said. The actual radiation rounds are not bad but am still so tired can't imagine what I will feel like in several weeks. I have also been staying the entire 8 hours at work which is making me more tired but just can't sleep. Will keep the sleeping aid nearby for those zombie days.

I am scheduled to do 36 rounds of rads and only 34 more to go. No problem with self care to and from rads, even went solo during entire chemo (except 1st round.) I always slept during the chemo injection and stayed awake for the following 3 days. My ride to radiation treatment is 30 minutes one way and my work is 70 min. the opposite direction so this weighed in my decision to go to STD during radiation treatment.

I work for a manufacturing company in SJersey, the company is relocating the entire process to Pa. with the entire move being complete next week. I am hanging in there through next week to assist with potential issues with employees and customers.

I am starting another trial this coming or following week that will continue for 3yrs, using a bisphosphonate. This trial will not be as involved as our first trial but again in hope to benefit me and other woman.

Do you have family to help support during chemo and rads?

Keep in touch, there may be another woman joining us from my Onc's office. In addition, if you find other woman who are in this trial invite them to join our group. There are non-trial woman who also stop in and help us along our way and provide answers to our questions.

smile,

brena

sftfemme65 · June 2008

Hi Everyone,

Thought I would add a little about my experiences with chemo. For me the worse SE were with A/C, I couldn't handle the dizziness and the feeling of just being so out of it mentally. I also went on STD. My 12 taxols were ok, I did develope that rash that brena had too but my doc and I both thought it was from the avastin....but here I am 3 weeks since my last taxol and the rash is gone so guess we were wrong. Another thing that has recently occurred that I found very strange was, I had nose bleeds through out my treatment and about a week ago they stopped, not a drop of blood since....weird. I don't know whats up with that but its fine with me, I wasn't crazy about that side effect.

cjw, speaking about trip neg bc, even if you are node neg it is highly recommended that you do chemo because of the reoccurrance rate.

I decided that I will do treatment on the 23rd and then fly out that afternoon. I don't expect to feel bad, maybe tired but I'm sure Vegas will make me feel better lol.

I went swimming today and it felt so great. I was worried I would get too much sun but the sunblock worked. I'm going to try to slowly get a tan.

My primary doctor, who I saw thursday because I was dizzy and felt off balance. He figured it was a sinus infection but insisted on doing a ct of my sinus and brain, just too be sure because of the avastin, make sure I had no bleed. I have to tell you waiting there in his office for 30 mins while the radialogist looked over the scan was a little (ok, a lot) scary. But all was good and it did show a sinus infection, so I'm on an antiboitic....doctor also wants me to have the onc test my vit D levels. Have any of you had that done?

Well that all for tonight, Talk to you guys later

If I haven't said it lately, I'm so glad to have you guys to talk/vent to, it sure helps

Teresa

carolynf · June 2008

Hi ladies,

Well, I had written some comments and lost them...Brena, I have the boys heading to soccer camp and my daughter is going up ME to a friends camp. So I will have a week away from them but I am coaching Allstars. My daughter is on the team and she will not be at the first week of practice so I need to send her w/a glove to practice w/her friend or else.. She is also heading to Colby college for basketball camp for a week. My youngest will be going to a conservation camp for a week to get his hunter safety course and boating course done. He then heads out to California w/his best friend for a coupple of weeks (his parents have a house out there besides here). I don't think I will be working all week this summer just w/the rads making me tired. I might surprise myself and work a whole week. You never know.

Teresa, hope you are all moved in and relaxiig by the pool. That's where I usually hang in the summer time. The ocean is about a 15-20 ride but when the tourist are here and the roads are busy and I am tired, the last thing i want to deal w/is traffic. I gather you have also had EKG and echo's because of the trial drug. They are really nothing. I get an xray every week during rads to make sure they are in the right place i guess. the technician explained it but i think my head was ready to leave.

Desi and Carol, Hang in there. Time flys during chemo (I think). I no longer have the bloody nose which i will say it was due to the Taxol. While on the taxol my hair started growing back around week 7 or 8. So i had hair when I got done the Taxol. I've met women at rads who finished in March and do not have hair. I think its our diet and maybe the supplementals that i took during chemo. I think standard treatment w/some alternative is kinda like ying/yang for the body. Listen to your body and make sure you hydrate (drink plenty of water). A women told me to drink gatorade the day before chemo beccause it helps w/the labs. not sure how true that is. I don't really care for gatorade but I did drink the one type of drink that they put out w/vit B12 in it.

My eyelashes are few and so are my eyebrows. My leg hair has grown in but is light and fine. I do have a nice tan going using sunblock 30. Onc. said no sun worshiping so i am not outside all day as I would be on a normal summer day. I do have raccoon eyes due to the suns brightnesss. I think that is an se of taxol or chemo itself. Well, I must bring the boys shopping for new soccer cleats and stuff for camp since its Sunday and I won't have to run around more than i have to during the week.

take care and try to laugh everyday!

Carolyn

S3K5 · June 2008

Hi Ladies,

It is good to hear all the updates about treatments and your life during treatments.
Teresa, hope you have a good trip to Las Vegas. Glad to know that yor nosebleeds are gone. I seem to have the same SEs as you with A/C - I feel dizzy and so out of it! I had to go on STD due to my cough and dizziness. Hopefully I should be able to work after the A/C rounds (two down, two to go!)

Brena, I hope your sleep pattern comes back to normal soon. Lack of sleep can really add to the already existing fatigue. I have read/heard that radiation can be tiring due to cumulative effect of the chemo. Our body goes thru so much during chemo! A break will do your body good.

Carolyn, how do you get the energy to do so much! You are such an inspiration to me! Do you have help to manage it all?

I feel there is so much fluid retention - soon after each chemo I weigh about four pounds more. Is this normal? My face and legs are puffy. I don't know if I am getting Avastin or not, but blood pressure is higher than normal (it could also be due to the saline solution from IV).

Brena, thanks for asking about my family. I have my parents here to help me out and my 19 year old daughter comes home every weekend to help out with laundry, etc (she is in college). She drives me to my chemo sessions and sits with me for four hours. I am lucky to have such a strong family support. My 13-yr old son doesn't know what is happening - at present, his main concern is my hair falling! DH takes care of all errands - groceries,etc.

How about you? How many children do you have? How about other family members' support?

Keep in touch.

Desi.

HensonChi · June 2008

Hi All,

I am from Chicago and getting ready to start E5103 this week...well I had the muga...now I go in for urine, blood and EKG on Thursday. I was glad to read that some of you said that in spite of the side effects you would do it all over again. Do they adjust the dosages or drugs the longer the trial goes on? I am 48 and just diagnosed with stage 2A ILC. 1/14 lymph nodes involved.

When the doctor asked me about participating, I said O.K. if it wil help the cause....and she basically said...don't be so altruistic because if you get the real deal this will help you!

I had a axillary lymph, lumpectomy on the right (1 cm mass) and a lumpectomy on the left to remove cysts (not cancerous) that might turn into something in the future.

So I am ready to go now on the chemo....I want to get going and put It behind me if possible...but there is always that chance that it may come up again. Anyway.......the info here is greatly appreciated!

HensonChi · June 2008

Hi All,

I am from Chicago and getting ready to start E5103 this week...well I had the muga...now I go in for urine, blood and EKG on Thursday. I was glad to read that some of you said that in spite of the side effects you would do it all over again. Do they adjust the dosages or drugs the longer the trial goes on? I am 48 and just diagnosed with stage 2A ILC. 1/14 lymph nodes involved.

When the doctor asked me about participating, I said O.K. if it wil help the cause....and she basically said...don't be so altruistic because if you get the real deal this will help you!

I had a axillary lymph, lumpectomy on the right (1 cm mass) and a lumpectomy on the left to remove cysts (not cancerous) that might turn into something in the future.

So I am ready to go now on the chemo....I want to get going and put It behind me if possible...but there is always that chance that it may come up again. Anyway.......the info here is greatly appreciated!

sftfemme65 · June 2008

Welcome henson,

I'm glad your on the trial. Are you trip neg? Looks like our little group is growing!

Teresa

brena · June 2008

HI Henson,

Glad you found us and welcome to the group. It would help us if you could fill in your stats about your BC.

The drug dosage is fixed using the A/C and Taxel throughout the trial, ask your Onc or Nurse for a copy of the trial E5103. You could also Google it and download a copy, definitely helpful as you progress. Dosages can be adjusted only per the protocol this is one reason to have a hard copy as I am sure does your Onc.

Let me make sure I understand; you had a lumpectomy on both breasts? Do you need to receive radiation to both breasts?

Will you be working during your chemo? Do you have a family history of BC?

Very glad you found us,

carolynf · June 2008

Good morning,

Welcome Henson. You have the get go that I had at the beginning after my lumpectomy. My onc wanted to wait til after Christmas for chemo so it wouldn't interefer...I said NO, i wanted to start before Christmas since it was already ruined by my lump being cancerous. You will find a lot of info here that will help you get thru. I am feeling great today and this is the start of week 3 rads. I think my breast is a tinge pink this morning. Not really sure due to lighting. Rainy day blues.

Desi, I have my husband who helps get the kids from here to there but I am his organizer to tell him where he needs to be. I have one of those eraseable calendars (big one) on the fridge. Even the kids look at it daily to know what is going on that day. BC (before children) I had 3 jobs and was going to school nights. I've always needed to keep busy. Sometimes reading 2 books at once. BUT the older I get it does tend to tire one out. I let my body tell me yea or ney. Took things slowly this weekend. Decided Friday night at 9:30pm while talking to my sister to have a cookout Saturday around 1ish. I hadn't gone shopping and I had 2 games in the morning. So when I got done the games, i dropped 2 kids off and picked up 1 to go w/me to help. Then remembered I forgot to call mom to have her come over. When I called her, my sister had called her at 10pm on Friday to let her know. They brought most of the stuff. I made a salad which was literally whipped together. Everything turned out fine. My husband was slow moving that day as he didn't know what was going on because he had been in the garage working on the 59 MGA for his daughters wedding. I can't wait to get that project out of my garage! It's a 3 bay garage but w/the MG, 3 Harleys, bicycles, a John deere tractor, my van does not quite fit in there. Well, I must be getting ready for work and my little guy needs to get out of the shower! He loves to just lay down and let the water hit him for hours if i let him.

Take care and smile at everyone today!

Carolyn

HensonChi · June 2008

I just posted my stats. I have the packet with the info. about the trial. I Will go and sign the release on Thursday for the trial when I go have my stats done.

My left breast was negative for cancer, but they said it was "busy". I guess lobular tends to mirror itself, so to be on the safe side they cleared out anything that looked like it might turn into something.

cjw · June 2008

Hi All

Well chemo started on thursday and so far not too bad. I felt a little woozy on Friday , then seriously fatigued (you guys weren't kidding) on Saturday. Had gone for a run, then took kids to the pool, then by 2 pm felt like I had severe jet lag. Went to bed, got up for dinner, back to bed, then woke up 7 am sunday morning feeling pretty normal. Went to work today and a little tired now but not bad. Do the side effects wear off after those first few days or will they come back b4 the next round? Not sure if i have the avastin or not, no bloody nose, but some headaches, which I normally never get. I also got a whole bunch of antinausea stuff to take at home and a neulasta shot.

Henson, I am in Chicago too-where is your trial? I am at Rush (don't know if I am supposed to say that) and live in the western burbs.

I do have tons of help (although my husband is out of town 4 days a week), but I have an understanding boss, great nanny and unbelievable family and community support, so I truly truly count my blessings.

all the best,

carol

cjw · June 2008

ps

am i the only one that had a mastectomy here?

sftfemme65 · June 2008

Cjw,

I also had a mastectomy, left sided. I plan on having my other breast removed when I'm done with treatment.

Teresa

brena · June 2008

Hi trial teammates,

Getting home late each day this week so xtra tired, won't be writing any books this week Wink

Carol,

The SE and symptoms you described were mine almost exactly, with each subsequent shot they lasted a few days longer. Once the SE left they did not return until the next shot, hopefully your SE will be the same or less frequent.

Very glad to hear you have a fabulous support system, definitely lean on them!

Never seamed to be any question on getting chemo, just when to start and what drugs for the reason's that Teresa mentioned + grade and size of tumor are other factors.

Completed rad 3 today only 33 more to go, give me strength! I had my bone and dexa scan completed and bone scan showed negative (as expected) for cancer and the dexa showed mild osteopenia. The bisphosphonate drug (from trial) will help me with problem.

Fourth fingernail detached and that baby hurt, three more hurt and I wish they would come off to stop the hurting. Typing does not help the situation but keep plugging along. Someone at work gave me a box of "hello kitty" band-aids to make light of the ordeal. I now have three boxes of band-aids to get me through until new nail growth. I am putting the tree tea oil on my nails hoping it will encourage new growth and quickly!

Teresa,

Tell us about the new house, how far from where you already live?

I promised no book so it is time to go, really enjoy hearing from everyone.

good night,

HensonChi · June 2008

CJW...I sent you an email!

cjw · June 2008

henson

where did you send the email ---i dont think i got.

Brena--good luck with the radiation-that sounds really intense in terms of number of sessions. thanks for all your kind support being on the far end of this. I am SO thankful I found this group.

Went out tonight with a girlfriend, no talk of cancer, totally fun. hopefully a couple glasses of wine isn't contraband on the program here.

Have you guys heard about Fomesta/Reclast? It appears to be in widespread clinical trials now, my onc. suggested looking at it after these trials conclude late summer.

cjw · June 2008

ps

what is a dexa scan--is that bone density?

brena · June 2008

Carol,

Wine is fine, this is one topic I definitely discussed with my Onc. In moderation is fine so do enjoy the good time with your friends. Laughter and friends are the best distractions even if temporarily.

I have not heard of the Fomesta/Reclast but will google for more information. If you find a good link attach in your next post.

Dexa scan is a test for bone density.

33 more rads to go, and three more days left to my work week.

Sitting here eating cookie dough, but what the heck it taste good!

take care ladies,

brena · June 2008

Carolyn,

Have you been asked or done a breast ultra sound (one with BC)?

Eyelashes and brows are starting to sprout ever so slightly, still waiting for the white skunk mark on the head to grow. I don't think I will be getting my first real haircut by the end of summer at this rate.

I would like to do something this summer but not sure what, can't be more than a two day weekend unless I jump rads on a Fri or Monday. What are you guys doing this summer for fun or a little distraction?

Is this your 3rd week for rads, damn I didn't realize you are that far ahead of me. Go girl!!!

laugh when you can,

carolynf · June 2008

Good Evening trial team,

Brena, I have not heard of a breast ultra sound. The only thing I have been doing is the Echo/EKG due to the trial. I have my next chemo on the 30th (I think its #3) and will talk to Onc then. Every week I have rads they do an xray to make sure they are where they should be. Which is good! Lucky you w/the eyelashes/brows. I still don't see anything yet. I think it all went to my head. I am starting to get some wicked waves on top. The heavy duty gel can't even keep them trained.

I am really interested in this Fomesta/Reclas. Anyone w/anymore info please share. I have been reading SE's again on Rads and avastin. I guess the tiredness and muscle aches are me. I will also ask my onc if he knows anything about them. Well, had another ball game tonight and am very tired. I am hoping to make it to work the rest of the week. Take care and I will be having a glass of vino or a Sam this weekend while relaxing...no rads.

Carolyn

Clinical Trial E5103

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