new plan/ gezmar & carboplatin

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new plan/ gezmar & carboplatin

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  • lemonpie
    lemonpie Member Posts: 183
    edited May 2008

    Well after a week my onc has determined that the weekly paciltaxol is not working to shrink the cancer in my lymph node so I will start Gezmar & carboplatin on Saturday.  Has anyone had any experience with this combo?   Desperate for some insight.  Oh and it has been determined that this is a new cancer and not a recurrance which is "good"   as it is hormone positive..  Any tips or advice are greatly appreciated.

  • Anonymous
    Anonymous Member Posts: 1,376
    edited May 2008

    lemonpie...I don't have any experience with those drugs, but have read posts from women on the mets board as well as on the 2nd cancer board about them. Hopefully you'll get some feedback either here or in one of those sections.

    ~Marin

  • TenderIsOurMight
    TenderIsOurMight Member Posts: 4,493
    edited May 2008



    Just dropping by to wish you well on Saturday, Lemonpie.



    Keeping up with your news, and hoping others who have had those drugs will comment.



    That is good news about hormone positive receptors in the node. So after chemotherapy, you'll be offered a hormonal. Lots of information on the hormonal thread.



    Let us know how you do this weekend. I'll be thinking of you.

    Tender

  • EyesOTex
    EyesOTex Member Posts: 194
    edited May 2008

    lemonpie from lufkin...is there something about Texas and triple neg?

    I started on Cisplatin/Gemzar May 2.  I think that Cisplatin is similar to Carboplatin in that it is platinum based.  However I think (chemo brain?) you said this CA is ER+ so I don't know aobut that; I thought the platinums were more for triple negative so maybe his thought is to hit both at once.  I am still learning the SEs. 

    I get Aloxi IV (day of chemo) and Decadron and Emend orally for the nausea (3 days worth).  It takes from 4-6 hours to do the chemo, depending, of course, on the pharmacy effienciency/crowd/demand.  I have 4 cycles of : 2 weeks on, one week off, one week on, rinse, repeat.

    I haven't lost my hair yet.  My mouth is sore but doesn't actually HAVE sores.  Muscle/bone pain.  Feeling kinda weakish.  Also sorry for myself, in case you hadn't noticed!   Wake up at 2-3 am nauseated and can't go back to sleep.  Will address this stuff when I see the onc. again on the 23rd.  3-4 days constipation & 3-4 days diahrrea, also lack of spelling skills. 

    ALSO...very important if you are at ALL prone to motion sickness, migraine AND THIS APPLIES TO ALL CHEMO, INCLUDING A/C/T:  Chemo gives me a heckuva migraine (I don't like to admit this to My Husband The Neurologist, but he's the one who saved me and saved himself from being murdured for the crime of chewing pretzels) SOOOOOOOOOOOOO...

    I take Reglan (metoclopromide) for that and its associated nausea.  Otherwise, I'd've killed myself the first time around.  If light and noise bother you, you have a migraine; get HELP.

    OK, I've forgotten the question.  Lemonpie, good luck and if I can help you at all please let me know.  I'll be thinking about you...even when my interweb connection doesn't work....

    dc

  • lemonpie
    lemonpie Member Posts: 183
    edited May 2008

    Hi EyesOTex.... i don't know about the Texas/Trip neg connection but I have to tell you I don't like the club!!!  Now this new cancer is trip postive.... WTH!!!!  Perhaps pos/neg will cancel each other out... Could I be so lucky.... anyway...Thanks for all the info with the SE's... I had my first treatment Saturday 5/17 and I have not had any issues as of yet....That worries me as I took 5 rounds of the Paciltaxol without any SE's and it didn't work...  I'm hoping this new combo will.  I am faithfully taking my anti nausea meds... First time around I took TAC combo and felt much worse but overall handled it pretty well too. I went ahead and buzzed what little hair I had off. It was just starting to grow back from the first treatment when I started the Paciltaxol and it started to thin rather quickly... could'nt handle that look so I just buzzed it and started wearing the scarves again.  Well I wish you and all the ladies/men dealing with this all the luck in the world and thanks to all for your replys.  lemonpie

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