Vitamin D....or.... D3?

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  • wishiwere
    wishiwere Member Posts: 3,793
    edited January 2008

    Thank you, I'll go check it out now.  I've been checked over the years but never found to have a thyroid problem till just as I was getting dx this past fall.  Started on levothyroxine in october, and am only taking 1mg, so heck that's not much.  My dog was taking 3mg a day! Laughing

    Thanks for the posting, I'll check them out! :D

  • lisametoo
    lisametoo Member Posts: 187
    edited January 2008

    Good article from Mike Adams:  <a href = "http://www.NewsTarget.com/009415.html">Sunlight emerging as proven treatment for breast cancer, prostate cancer and other cancers</a>          

  • cayenneblue32
    cayenneblue32 Member Posts: 78
    edited January 2008

    Rosmary-

    Why shouldn't you take calcium carbonate if on thyroid medicine? I've been on synthroid for about 25 years, and I take calcium carbonate as my calcium source (not at the same time).  

    Should I be taking another form of calcium instead?????

    Theresa 

  • Blundin2005
    Blundin2005 Member Posts: 1,167
    edited January 2008

    Hi Theresa,

    If I can add to this while you are waiting for Rosemary's reply...

    go to www.jama.com and download this article .....

    "Effects of Calcium Carbonate on the Absorption of Levothyrovine" Singh, et al Jama June 7, 2000, Vol 283, No 21 Pg 2822.

    Essentially T4 is blocked by calcium carbonate significantly.

    I tried to paste my pdf file but it doesn't work here...sorry....don't know what I'm doing wrong. 

    I've been on meds since the mid '80's for the thyroid.  

    Best wishes.. 

  • wishiwere
    wishiwere Member Posts: 3,793
    edited January 2008

    Interesting thread.  Thanks for all the input! :D

  • Anonymous
    Anonymous Member Posts: 1,376
    edited January 2008

    Marilyn, what I understood from reading Jama article it wasn't the calcium carbonate.  The participants were told to take it at the same time.  After all was said and done, it was suggested to take it hours after taking thyroid med. 

    I take cal citrate.  I take it no sooner than four hours after my Synthroid.  So, I'm wondering if I understood the article correctly.

    Shirley

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited January 2008

    Theresa,

    As Marilyn said, carbonate interferes with your thyroid med.  It's in the hand-out that comes with the meds if you can find it in all the small print.  That was the only warning I read about calcium, so citrate is the better choice.  But wait out the 4 hours till you take calcium, just in case they come up with new research saying wait 4 hours.

  • cayenneblue32
    cayenneblue32 Member Posts: 78
    edited January 2008

    Hmmmm........

    I wonder if it's a problem for me, if my thyroid tests come out okay? (I'm tested every six months). My dosage has been the same now for about 15 years, since my levels always test within the normal range (and at the high end of normal, at that) 

    Wouldn't it show my thyroid levels as being low, if indeed the tums were interfering with synthroid's absorbtion? I never take it within four hours of the synthroid - it's usually more like 8 hours. Would taking citrate instead raise my thyroid levels, making me need an adjustment to my dosage???

    My concern about the citrate is that since only 20% of it is elemental calcium (the type you need), that I'll have to take huge doses to get me up to where I need to be.

    Any comments??? Smile

    Theresa 

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited January 2008

    Theresa,

    Sometimes they put those warnings in for the few it might harm.  If all is going well for you, the next time you talk with your Dr. he might know the answer.   If you changed to citrate, it's possible that you might need a lower dose of synthroid, or then again, nothing in your levels will change.  I don't know how long you've been taking calcium, but when you started, do you remember having to tweak your synthroid dose?   It might not be bothering you to take carbonate.  Check with the Dr. though.

  • cayenneblue32
    cayenneblue32 Member Posts: 78
    edited January 2008

    Thanks Rosemary-

    My synthroid dose hasn't changed in years, even after starting the calcium carbonate. It looks like it works for me - especially since my dexa scan came back with no "measurable" loss from the year before. I think I'll stay with my tums for now, and ask my endicrinologist next time I see him!

    Thanks again-

    Theresa 

  • Blundin2005
    Blundin2005 Member Posts: 1,167
    edited January 2008

    Hi all,

    My labs are back. All seems well according to the lab doc. 

    A recap...2 years 3 months on Arimidex (and counting).  I did not tolerate the med well at all, to say the least.  Certain that the hypo thyroid and arthritis made this even worse....but the magnesium supplement made it tolerable again.  

    I visit the thread 'Arimidex vs no hormonal therapy' often.  But I've concluded to stay with Arimidex and tweek my other meds and diet around that need.  So far, so good. 

    I asked for a check on the D3, Mag, calcium, etc.  The test for vit D is not covered under the national health system...I paid 35 euros for the test.

    It is worth a mention to say that I began magnesium supplements (magnesium pidolate) in September...and sporadically took my supplement of D3 with calcium carbonate for many months... (thyroid meds affected if not taken four hours before calcium carbonate).

    I'm in a sunny climate (most of the time).  We eat much dairy in the form of cheese (CLA rich especially), vegetables and fresh fruit.  I admit to my passion for chocolate, coffee in the morning, and wine with dinner.

    My exercise increased significantly since taking the mag supplement (and getting a puppy!).  No weight loss yetFrown.  Probably the holidays had something to do with it.  I'm reading again the healthy diet thread here..the ladies help to motivated the cut back on the portions and sweets.  However, quality of life seems to creep back into my rational when selecting the portion of my mealsWink

    I'm satisfied with the results and relieved to know I'm on course nutritionally with diet, etc.  

    My WC took a dive...lowest since last March '07.  Maybe the flu in December took the count down..or the dreary January weather....unusual amount of rain.  I'll increase the mushrooms and beets.  I've been craving both....interestingly. 

    Vitamina D Totale (25-OH-D) = 31  {range ng/ml 10 - 45}  They also made a notation that the range changed on 4 Dec 2007 for Vit D3 9 - 38.

    Potassio Siserico (Kaliemia) = 4.2 {range mEq/l  3.5 - 5.5}

    Calcio Sierico = 8.2 {range mg/dl 8.80 - 10.5}

    Sideremia (Iron) = 83 {range mcg/dl 40 - 151}

    Magnesio Sierico = 2.3 {range mg/dl 1.8 - 2.5}

    About the Moc....the doc didn't want to do the lumbar/femora because the lumbar had so much arthritis the DEXA can't see thru?...he said that he didn't want to take my money for no reason.  Instead, he did the hips and femora.  I have arthritis in the hips too, but not as severe.

    I was happy to hear that I am not at risk for fracture....an improvement. Yehhh.  The moc cost 80 euro but they refunded 20 euro for the change in bones scanned.

    Hope that to share this info helps someone else ... especially those just beginning on the hormonal therapy path.  

    Best wishes to all...as always.

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited January 2008

    Marilyn,

    Your labs are very interesting because you stayed in proper range for magnesium even though you're adding it every day.  You might have been on the low side before supplementing?  This is what I suspect, we are low and don't know it and crazy side effects start to happen and we blame it on everything else.  Just my musings, of course.

  • Blundin2005
    Blundin2005 Member Posts: 1,167
    edited January 2008

    Rosemary,

    ...the numbers say a lot.  I couldn't agree with you more.  The down sides of magnesium deficiency (joint pain, anxiety and depression) were a heavy weight to carry on top of BC management. 

    I can't comment on the whys and wherefores of it all...but it is so worth checking into this and I recommend it to anyone.  I may have mentioned that my neighbor went through radiation of her thyroid....the docs supplemented her with ... you guessed it....cal / mag / vit D3.  She's feeling so much better these days ... smiling again.  It's worth it to check.

    I am eternally grateful for the knowledge shared by everyone here on the boards, and especially to you and BBS for the information on magnesium deficiency, thyroid function, calcium supplements...etc.   I probably sound like a sappy commercial, and I really don't care if I do, ..... thanks soooo much.  Every day is hopeful again.

    This little 'ol lab report is the culmination of major sleuthing (as Saluki called it) from March of last year until now.  I was so curious to see how the numbers would come out.  

    I think I'll go and get a piece of dark chocolate and a glass of red wine to celebrate!  Join me?  I had pizza with mushrooms and CLA rich cheese for lunch.  It's skinless turkey cooked in olive oil, white wine and greek olives..seasoned with rosemary and sage.  Probably a tossed salad to go with it...and probably a Vermentino.  Salute my friends.

    Best wishes to all...as always

  • Anonymous
    Anonymous Member Posts: 1,376
    edited January 2008

    Marylin, I'm so happy that you feel so much better.  I've been reading your "joy" over this. 

    Okay, I'm confused.  You said your Vit D test came back

    Vitamina D Totale (25-OH-D) = 31  {range ng/ml 10 - 45}  They also made a notation that the range changed on 4 Dec 2007 for Vit D3 9 - 38.

    My lab (Lab Corp) says that 32 - 100 ng/ml is normal.  I wonder why the big difference in values?

    Can someone please explain? Undecided

    Shirley

  • Blundin2005
    Blundin2005 Member Posts: 1,167
    edited January 2008

    this information taken from google search.... http://courses.washington.edu/bonephys/opvitD.html 

    another very good reference ... http://lpi.oregonstate.edu/infocenter/vitamins/vitaminD/

    Much more information available at this site.  The table doesn't copy well so you may want to go to the web site to see it clearly.  Hope it helps Shirley.... 

    Vitamin D levels in serum

    25 (OH) D Levelng/ml nMol/L
    Deficientless than 8less than 20
    Insufficient8-2020-50
    Optimal20-6050-150
    High60-90150-225
    Toxicgreater than 90greater than 225

    The normal values are higher than previously used. The definitions of normal and optimal are still debated. Heaney suggests there are two ways to define the optimal level: that level at which calcium absorption does not change further on giving extra vitamin D, and that level which will avoid increases in parathyroid hormone. Both approaches revealed serum 25(OH)D levels of 32 ng/ml. A survey in a general medical hospital found that 57% of hospitalized patients had levels lower than 15ng/ml. This high prevalence of hypovitaminosis D might contribute to osteoporosis. Excess vitamin D, on the other hand, can accelerate bone resorption. In patients referred to a bone clinic, 4 patients with high 25(OH)D levels (53-89 ng/ml) from dietary supplements had hypercalciuria and osteoporosis, and the bone density improved over 3 years after they stopped their supplements.

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited January 2008

    Marilyn,

    I'd love to join you.  But I gave away my dark chocolate, I couldn't throw it out and I drank my red wine.  It was a few days old so it had to go....down the hatch that is.   I need to go shopping again.

    I can't seem to like a wine that's been opened more than 4 days.  I swear the taste changes too much.

  • Anonymous
    Anonymous Member Posts: 1,376
    edited January 2008

    Thanks, Marilyn.

    It's odd how more doctors are ordering this test.  One of my friend's (who has fibromyalsia) doctor (Rheumy) ordered the D test.  Her's came back 15 or 17 (can't remember).  He had her on the D2 prescription.  It will be interesting to see how that one turns out.

  • Blundin2005
    Blundin2005 Member Posts: 1,167
    edited January 2008

    Buon giorno bella donna!

    Rosemary,

    Another time then....as for the chocolate, I'm not yet convinced to "give it away"....but compliments to you for your strength.  As for the wine open more than four days...I agree...it changes flavor.  In fact, my DH recently told me that it is considered an insult here to serve guests from an bottle of wine that is already opened.  A British friend of ours did so....I explained to DH that an open bottle of wine in US is common....he grumbled something and we let the topic go.Wink

    Taken from.... http://lpi.oregonstate.edu/infocenter/vitamins/vitaminD/

    Did you read this?  I'm intrigued...and hopeful.

    Cell Differentiation

    Cells that are dividing rapidly are said to be proliferating. Differentiation results in the specialization of cells for specific functions. In general, differentiation of cells leads to a decrease in proliferation. While cellular proliferation is essential for growth and wound healing, uncontrolled proliferation of cells with certain mutations may lead to diseases like cancer. The active form of vitamin D, 1,25(OH)2D, inhibits proliferation and stimulates the differentiation of cells (1).

    Cancer

    Two characteristics of cancer cells are lack of differentiation (specialization) and rapid growth or proliferation. Many malignant tumors have been found to contain vitamin D receptors (VDR), including breast, lung, skin (melanoma), colon, and bone. Biologically active forms of vitamin D, such as 1,25(OH)2D and its analogs, have been found to induce cell differentiation and/or inhibit proliferation of a number of cancerous and noncancerous cell types maintained in cell culture (58). Results of some, but not all, human epidemiological studies suggest that vitamin D may protect against various cancers. However, it is important to note that epidemiological studies cannot prove such associations.

     

    Gotta love that balance issue .... I think this is at the core of the pain issue for some of us...and others who have no SE probably have a better distribution of these vitamins as well as healthy parathyroid activity...god bless them all. 

     

    Shirley - glad always that you found the information you needed.   Hope that your friend gains back her health too.   I think too much politics is detrimental to our health...we need a surgeon general warning on the TV adsLaughing...I can only imagine how everyone in US must be feeling inundated with commercial after commercial.  And we in Italy now are again intrigued by our dysfunctional Parliament.  It's the same everywhere.  So for today I don't worry....I take the puppy to the lake and get some Vit D for me as well. Wishes for you to find similar comfort.

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited January 2008

    Marilyn,

    I was listening to a lady on TV the other day and she was saying that since D is a fat soluble vitamin and if we're over weight it's going to get stored in our fat cells and not go to work for us. 

    I think mine is working because my hip stopped hurting.  Imagine, just one small vitamin that can change our world.   How much C do you take? Or eat?   I keep reading lately about C and arthritis.  

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited January 2008

    Theresa,

    I have read too many things about unnaturally changing our stomach acid environment by taking antacids on a daily basis.  Did a Dr. suggest you take tums for calcium?  

  • Blundin2005
    Blundin2005 Member Posts: 1,167
    edited January 2008

    Rosemary --

    Good point about the fat storage of vit D.  This might be another good reason to loose some pounds....

    Glad to hear that your hip pain is under control....every little bit helps.

    About the vit C....I took supplements for years 1000 mg per day...the horse pill size....but now I take it only in my food.

    We eat an orange every day.  Our tree provided us with oranges from begining Dec to just last week.  And yesterday, when I donated to the local Associazione Italiana Per La Ricerca sul Cancro ... I received a bag of Sicilian blood red oranges....soooo good.....for 8 euros....good deal, no?

    The lemon tree blooms year round, but we run out usually sometime in the summer.  We use the juice in cooking ... and make water ice in the summer.


    We eat salad of all types every day....radicchio is a favorite...especially with balsamico vinegar, oranges and black olives.

    But something I overlooked as a good source until I searched the web page that I just posted....garlic, rosemary, sage, parsley.  We keep plants and use fresh everyday in the cooking. I didn't realize how much nutrition they added!  a surprise!

    We use red peppers a lot too, but canned and skinned, not fresh because my DH has digestive problems.  I cook these with tomatoes, garlic and chicken.

    Foods are seasonal, so it depends the season what is available.  It's artichoke season soon and one of my favorites. 

    Probably I get the RDA but maybe a supplement of just a little more might help.  I'll let you know.  I suspect though that the damaged bone due to arthritis is not reverseable...but, one can never be absolutely certain of anything..so I'll give it a try.

    Thanks for the info.

  • cayenneblue32
    cayenneblue32 Member Posts: 78
    edited January 2008

    Hi Rosemary-

    The doctor just said to take calcium - didn't mention what kind. I actually only take two tums a day, so I don't know if it's enough to hurt my stomach acids, or not.........  (though they did have something like this on an episode of House I saw the other night) Smile

  • Anonymous
    Anonymous Member Posts: 1,376
    edited January 2008

    Marilyn, here in the states a women's vitamin is advertised with extra D for breast health.

    Rosemary, I also read that about D being stored in fat.  Speed up the damn treadmill!

    About stomach acid...Dr. Rosenfeld on Fox News Sunday morning said that some people think by taking apple cider vinegar that it helps with too much acid.  Seems odd, but I've heard this before.  He says people tout that ACV helps lower cholesterol and other things (Joan uses it).  He said there's no proof, but that if it didn't hurt you or interfere with meds by all means take it.  He said 1 tablespoon a day is what people told him they took. 

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited January 2008

    Theresa,

    Yes, it would.  Your doing it daily so you are changing the natural environment in your gut.  It changes naturally overtime and we lose stomach acids as we age.  Then there's all hell to pay if it gets too low.  We need our stomach acid to break down the calcium, so  nutralizing our acids doesn't seem to compute.

    I did see that House show and it was quite over dramatized, the guy winding up with a heart transplant.  All things are possible, but that seemed off the walls.

    They do make chewable calcium, just try to find one without oxide magnesium.  Oxide doesn't absorb as well as citrate.

    Shirley, that's good to know about ACV.  I know Joan takes it but I didn't know why.  I'm wondering how people know they have too much stomach acid because you get the same symptoms when stomach acids are too low.  I guess there is some sort of PH test out there.  When I get heartburn, I eat a couple of pieces of chrystallized ginger.  All gone.

  • cayenneblue32
    cayenneblue32 Member Posts: 78
    edited January 2008

    A question then.........

    If calcium citrate is the answer, and only 20% of calcium citrate (elemental) is absorbed, does that mean you need to take five 1000mg tablets daily to get your required daily dosage?  

    That was the reason I started with the calcium carbonate to begin with - the 40% elemental calcium absorbtion sold me!!  

  • Blundin2005
    Blundin2005 Member Posts: 1,167
    edited February 2008

    Yesterday a belated birthday presents arrived in the mail from my son.  One of the presents was a book entitled "Healing with Whole Foods--Asian Traditions and Modern Nutrition"...Paul Pitchford (Third Edition). 

    I thumbed through the index and found.."15. Calcium" then below was written "The Magnesium Connection" ... "The Hormonal Activity of Magnesium" ..."The Relaxing Effect".  I absolutely had to look immediately.

    It's obvious that I can copy and paste the whole book ... however, the magnesium connection is of particular interest.

    ...so it said...

    "It is common knowledge that vitamin D is essential for efficient calcium utilization.  In response to this information, the dairy industry has fortified nearly all available milk with synthetic vitamin D3.

        For many years, magnesium also has been recognized as valuable in calcium absorption, but its absolute necessity has been underscored in several recent human experiments.  In one, calcium and vitamin D were abundantly supplied while magnesium was withheld; all subjects in the experiment except one became calcium-dificient.  When magnesium was reintroduced in the diet, calcium levels rose dramatically. 2"

    Chapter 15: Calcium

    2.  Regtop, H.  Is magnesium the grossly neglected mineral?  International Clinical Nutrition Review 3:pp 18-19, July 1983.

    "Calcitonin is a hormone which increases calcium in the bones and keeps it from being absorbed into the soft tissues.  Magnesium stimulates calcitonin production and therefore increases calcium int he bones while drawing it out of the soft tissues.  Many forms of arthritis are characterized by excess calcium appearing in the soft tissues while skeletal calcium is lacking."

    This helped explain why the magnesium worked so well for me to decrease the joint pain and improve my cognitive abilities. 

    .... also noteworthy was ...

    "Photosynthesis an extremely complex and poorly understood process, takes place in plants in the presence of sunlight and results in the fomation of chlorophyll.  All plants touched by sunlight contain chlorophyll, but the green plants are by far the most concentrated sources."

    "Many of the benefits man gets from the sunshine he can get from greens.  Anyone in the city should especially think of greens as a means of getting sunshine to the body. -- Dr. Bernard Jensen, from Health Magic Through Chlorophyll"

    Did you know that it was only in 1988 that "the Surgeon General of the US acknowledged  the value of a good diet, while simultaneously condemning typical American eating patterns.

    The book only arrived yesterday -- has anyone else here read this?  Probably Rosemary for sure....

    The blurb on the front cover said "This book has the feel of a life's work: it's packed with information essential for anyone seriously investigating the relationship between food and healing." -- Yoga Journal

    I think that describes us ....  

    Now I'm off to read about calcium absorption....

    Best wishes to all...as always 

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited February 2008

    Theresa

    The advice out there is not to go over 2500 mg of calcium regardless of how much of it we absorb.  That's why we take D and magnesium with it to aid in absorption.  Eating high vitamin K foods are important, as is potassium.

    We can get in trouble without taking magnesium with calcium because calcium can attach to organs and such, so getting it absorbed where we want it to go, is very important, and not going overboard with it is the most important.

    Marilyn,

    I didn't read that book.  I can't believe I might have missed one.  I never spent so much time in my life over calcium, mag and D.  There always seems to be more info everyday on one of them.  Iodine is becoming my latest project.

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited February 2008

    Here's something about taking vitamin C with our calcium so we'll have acid in our stomachs for proper breakdown and absorption:

    http://www.foodingredientsonline.com/content/news/article.asp?docid=87375ad0-4161-4213-9124-b0334c2f3ba7&atc~c=771+s=773+r=001+l=a&VNETCOOKIE=NO

  • Anonymous
    Anonymous Member Posts: 1,376
    edited February 2008

    "According to the magazine "Innovations in Food Technology", calcium lactate gluconate has a very high absorption, with 10 times greater calcium solubility than calcium gluconate alone, and 140 times greater solubility than calcium citrate."

    Are we supposed to change our citrates for these other forms?

    I do take Vitamin C with my calcium.  Hmmm...don't know if it helps.  We'll see.

    Shirley 

  • Rosemary44
    Rosemary44 Member Posts: 2,660
    edited February 2008

    Shirley,

    If we don't pass our dexa scan then I would consider trying another type of calcium.  If your passing or not getting any worse, then your calcium is working for you.  She was also promoting a liquid type of calcium which I have read in the past is better absorbed but I couldn't find any research on that, but I take a liquid anyway just in case it isn't a sales pitch.

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