Diet or Supplement Curcumin?

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The more I read the more tricky these supplements become. This whole subject has made me rethink what I'm taking and try to make more judicious choices as to what I want to get by diet and what it may be wise to supplement. The other day I was reading in Nutrition Action Health Letter about another highly touted supplement which I was taking but gave up because of my gastrointestinal problems-Curcumin

Apparently, Curcumin is notoriously hard to be bioavailable and "only a fraction of the curcumin in pills seems to be absorbed or retained by the body."  "Even after swallowing large amounts levels in the blood are miserably low".  The math for curcumin in food is no better.

"Cooking with curcumin may help."

"The tumeric used in curry is put into hot oil and cooked," notes Cole.  "Maybe that delivers curcumin better than capsules filled with curcumin that has been extracted from tumeric with an organic solvent."  Coles bottom line "it seems safe to take up to two grams of curcumin a day but I can't tell you its going to do anything."

(Cole is a researcher at UCLA)

And the other question he brings up is "What Happens if you reach levels strong enough to kill cancer cells?" " I don't think  the current studies can say what the safety of curcumin would be under those circumstances."

( Nutrition action also warns if you are on prescription meds to be careful about the kind with added pepper extract.  "while the extract may increase your body's absorption of curcumin it can also interfere with the metabolism of all kinds of drugs." says Cole.)

Sound to me like a properly cooked curry will get you more benefit than the amount of capsules you could tolerate at least for me.

Also, the trials with this supplement have been notoriously high doses.  MD. Anderson was using 8 grams a day with patients with inoperable pancreatic cancer.

The studies with Alzheimer patients is how well they can tolerate 2 to 4 grams a day and "whether it lowers inflamation, oxidative levels and cholesterol levels. And one of the studies will also see if it slows the decline of scores on cognitive tests."

Comments

  • lindaDK
    lindaDK Member Posts: 99
    edited October 2007

    I agree with you about what to get from foods or supplements, if you figure it out, please let me know.  I don't know what the answer is.  I'm still trying to sort the 'list' I received the other day out.   I'm also finding different opinions depending on who writes the article.  The only ones I have come to a  conclusion on to supplement so far is CoQ10, ALA/NAC. The rest I'm still researching if adding certain foods to daily diet would work.   

    I did find a interesting site that will lists the important nutrients and what organic foods are rich in that particular source of nutrients.      

     http://whfoods.org/nutrientstoc.php

    Example for Omega 3's 1/4 c a day of raw organic walnuts will provide 2.27 g . 

  • TenderIsOurMight
    TenderIsOurMight Member Posts: 4,493
    edited March 2008



    Yes, I came to the same conclusion about Curcumin. It's a wonderful natural spice and may interfere with chemotherapy resistance but sadly it doesn't get much beyond the gut wall. Now that will limit any drug!

    I still use it in cooking as I like the flavor...



    I took a look at the supplement list thread. Gosh, do you believe I don't use supplements, albeit I do take 1000mg of Vitamin D and 1200 mg of calcium citrate (split dose). Do you think I'm missing anything big? I've thought about grape seed extract a little, yet am concerned about what's added to it.



    Thanks for the link, Linda. That's very helpful.

    Tender

  • lindaDK
    lindaDK Member Posts: 99
    edited October 2007

    heres more food for thought.  Is anyone familiar with a site called consumerlabs.com ?  They test supplements/herbs for their labeled amt, purity, ability to break apart, etc. You have to subscribe to their site and it does cost to get to the results.   Curiosity got the better of me so I did subscribe.    Here is some info on calcium supplements.  One product for calcium/vit d failed there tests due to higher than "acceptable" amt of lead.   

       

    quote of calcium/vit d and what they test for  

    Quality Concerns and What CL Tested for:
    Like other supplements, neither the FDA nor any other federal or state agency routinely tests calcium or vitamin D supplements for quality prior to sale. However, quality issues can include the following:

    • Labeled Amount - Does the product really contain the labeled amount of calcium and vitamin D? While calcium is an inexpensive raw material, it can be bulky, making the formulation of calcium supplements complex. If not manufactured properly, products may not "pack in" the labeled amount of calcium.
    • Purity - Many sources of calcium naturally contain other minerals such as lead. In children, infants, and fetuses, even low levels of lead can adversely affect neurobehavioral development and cognitive function. In adults, lead at somewhat higher levels can cause elevated blood pressure, anemia, and adversely affect the nervous and reproductive systems. Lead is of particular concern during pregnancy as the mother can deliver it to the fetus.
    • Ability to Break Apart for Absorption - For a tablet to be most useful, it must fully disintegrate prior to leaving the stomach, delivering its contents for absorption in the gut. Some tablets are not properly made and can pass through your body completely or partially intact, depriving you of its ingredients. Remnants of such products are sometimes found in the stool. This happens, for example, when a tablet is too tightly compressed (too "hard") or is too thickly coated.

    ConsumerLab.com, as part of its mission to independently evaluate products that affect health, wellness, and nutrition, purchased calcium and vitamin D supplements sold in the U.S. and tested them to determine whether they 1) possessed the claimed amount of calcium and vitamin D, 2) were able to disintegrate fully to be available for absorption and 3) were free from unacceptable levels of lead ."

    Is it acceptable to list brand names here?  I will do so if its ok.   I have also looked at other supplements, vit c,e, several name brands didn't pass  there tests.   ALso Saluki, you may be interested in the results on Milk Thistle.      

    more info about lead testing: "Although the FDA acknowledges the dangers of lead exposure, it has not set limits on the amount of lead in dietary supplements - nor has any state other than California. California requires a warning label on any supplement containing more than 0.5 micrograms (mcg) of lead per daily serving for a magnesium-only supplement or 1.5 micrograms of lead for supplements that also contain one gram of calcium - such as these two products. Although not dangerous in and of themselves, these products significantly and unnecessarily contribute to lead exposure. It is advisable to get as little lead as possible - particularly for children and fetuses because low amounts can affect their mental functioning.

  • saluki
    saluki Member Posts: 2,287
    edited October 2007

    Yes Linda,

    It is a very good source of whats in your vitamin.  Although I don't subscribe (I should) I've gleened some very important info from it.  Unfortunately, unless you subscibe you can't find out which is at the top and which are at the bottom.

    But it has given me, even without a subscription an  idea what to be leary of.

    A few years ago they analyzed Co-Q10 and astoundingly enough one of the brands did not contain any Q10!!!!

    They also have done calcium before although not with the vitamin D and I remember being shocked about lead being contained in some brands.  

    I think you made a good decision getting a subscription.  When my WorstPills.org from Public citizen subscription expires I may do the same. 

    I've been looking for calcium without the vit D since I am already taking 2400 IU. of D3 

  • Anonymous
    Anonymous Member Posts: 1,376
    edited October 2007

    I sure hope Vitacost's brand, NSI (think), is good because I used lots of theirs.  I probably should subscribe also.  They tease a little then want to to subscribe.  However, it's probably worth every penny to know if you are getting the right "stuff."

    Shirley

  • Anonymous
    Anonymous Member Posts: 1,376
    edited October 2007

    Susie, I take Vitacost's Calcium citrate malate and and also their D3.

    Now I need to join ConsumerLab. Undecided

  • abreast_of_life
    abreast_of_life Member Posts: 44
    edited October 2007

    Hi,

    I have read that turmeric or curcumin reduces tumours and research has been done to prove this.  I had a mastectomy in 2003 and am interested in anything natural that has proven health benefits.  Recently, my husband's doctor put him on chemo drugs for his psoriasis which got very bad.  I disagreed with this treatment believing that the right diet and supplements would take care of it.  The chemo did clear it up temporarily and then it returned fast and furiously.  I read about turmeric and went and bought a big 250 gram bag of it in the supermarket.  It is also available in Indian grocery stores.  My husband started taking a teaspoon a day in juice and within two weeks it had cleared completely.  I was so amazed that I started taking this myself daily.  I don't believe that the capsules offer enough of the stuff and it works out very expensive.  Ideally one needs an organic source.  I have read that cancer sufferers can safely take 8 grams a day for 3 months at a time.

    Take best, best care.

    Love and blessings

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