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itslisalouwho
itslisalouwho Member Posts: 74
edited June 2014 in HER2+ (Positive) Breast Cancer

if this is old news to some of you......

BUT...it's new news to me, and I am EXCITED!

If you are Her2/neu +++, you must Google "Neuvac".  It sounds SO VERY promising!!!

Edit:  it isn't Neuvac.....it's Neuvax....  :)  Sorry about that.

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  • bluewillow
    bluewillow Member Posts: 779
    edited October 2007

    HI and thanks for sharing this!  I hadn't heard about it-- is this in place of Herceptin?  And better than Herceptin? 

    Mary Jo

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  • itslisalouwho
    itslisalouwho Member Posts: 74
    edited October 2007

     This is what I have found out.  They are just starting phase III.  From what I understand, it can be used with Hercepton, or without it.  With far less side effects.  I'm excited!  :)

    The following was copied and pasted:

    In the first of two portions of the meeting Dr. George Peoples summarized data from the Phase I/II clinical trials he conducted with NeuVax in over 200 breast cancer patients including the most up-to-date analysis and data. The points presented by Dr. Peoples included:

    • An optimized dose of NeuVax
    • A demonstration of therapeutic activity through assessment of disease recurrence with a clear difference between the control group (not given NeuVax) and treatment groups
    • A greater than 4-fold reduction in disease recurrence in patients receiving the optimum dose of NeuVax
    • No recurrence to-date in patients receiving the optimum dose plus semi-annual boosters of NeuVax
    • NeuVax has no Maximum Tolerated Dose (MTD) because it is highly specific and has only mild side-effects
    •100% of breast cancer patients in Dr. Peoples' studies responded to NeuVax regardless of level of HER2-expression

    I WANT to be in the phase III trial, but you have to have been node positive.  Sounds like a great trial to get in for ladies that are node positive!

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  • ps123
    ps123 Member Posts: 221
    edited October 2007

    It sounds like it's a vaccine, I think.  Here's a couple of links:

    http://www.apthera.com/products.php?id=3

    http://www.apthera.com/end_of_phase_2_meeting.php

    Pat

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  • itslisalouwho
    itslisalouwho Member Posts: 74
    edited October 2007

    Yes, they are calling it a vaccine.  Although, it's purpose isn't to prevent her2 cancers....it's to treat.  Which seems odd to me.  I thought the word "vaccine" was used only to prevent.  I guess not. 

    Here's the link I tried to copy and paste from:

    http://www.apthera.com/end_of_phase_2_meeting.php

    wait...that is the link you just posted.  haha

    Here is another, if anyone is interested:

    http://www.apthera.com/products.php?id=2

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