Scared thick uterus lining

Hi living in paradise,

My uterus lining went from 2mm before starting Tamoxifen to 17 mm 4 months later. My situation is probably different from yours because I’m post menopausal, no periods to remove the extra thick lining. Had a hysterectomy to solve the issue and continue on Tamoxifen.

Do you know how thick your lining is? Good no polyps or fibroids. I hope you get answers. Hopefully someone else with more information will write in

I was on tamoxifen for about 6-8 weeks and noticed uterine pain very quickly.Had ultrasound showed 18mm thick. Did the gene test at the same time and turns out I don’t metabolise tamoxifen. Had d&c and biopsy and got the all clear. Apparently it’s not rare for this to happen so try not worry too much.

Tamoxifen can definitely impact your uterus and more often than not does make the lining thicken. I had the "biblical" period after starting Tamoxifen - 40 days and 40 nights ha. Triggered the whole biopsy effort etc. I haven't had an issue since, but my Gyn says to report any bleeding since I am now post menopausal. It is frustrating and exhausting to have concerns about the side effects of the meds you take. Hope all goes well with the procedure and Salamandra I hope you have benign results.

Year 4 of tamoxifen I had a thickened lining.at 10mm I was getting an ultrasound every 6months. Went in for a quick d & c was found to have an endometrial polyp and everything was benign. My gyno and onco said many women have thickened lining while on tamoxifen. They both said they just need to be kept an eye on. I opted for a d/c rather than watchful waiting. That was last August. Just had my ultrasound last month and normal lining.

Pinger you don't mention whether you are close to menopausal age which could definitely have an impact on what you are experiencing. That being said I think you are taking the right course and doing further investigation especially with known fibroid issues as well as a small cervical polyp. It is very common for tamoxifen to cause an increase in your uterine lining. My gyno has always told me things are fine but to watch for unusual bleeding . But that is when you are post menopausal. Things are a little bit trickier to monitor premenopause. Sorry for the stress and worry, hope everything checks out benign for you.

Hi eauclaire

My uterine lining was 2mm when I started Tamoxifen and 17 mm 4 months later. I wasn’t taken off of Tamoxifen but had a hysterectomy so I could continue taking it. I was 61 and post menopausal at that time. I didn’t want to switch to AL medication instead.

sounds like your lining is getting thicker but no where near how quickly mine did. I just know my lining thickness was out of control. Why would you need a biopsy? Are you having bleeding? Let us know what your Oncologist recommends

I was peri-menopausal before starting on Tamoxifen, and after 15 months on it, I had a massive bleeding. The vaginal US showed a 24 mm thickened uterus, but in turned out it was a large - benign PHEW! - endometrial polyp. My MO did take me off Tamoxifen though, and advised to stay off it.

Thanks Rah for your well wishes. Since the ultrasound which uncovered 14mm lining, I ended up getting a very heavy period after not having a period in 8 months and another period the following month. So even though I'm going to be 56 this year I am clearly not going into menopause. Would having a period decrease the lining?

I did end up getting a uterine biopsy which was interesting because the gynecology oncologist couldn't see the cervical polyp that my regular gynecologist mentioned. Maybe it detached with the heavy period? They did find a benign endometrial polyp which I am planning to have removed soon. Rain, I did ask about whether I should stop my Tamoxifen usage which is only 5mg a day but both. MO and GO said no. Are you on something else? Hope you are doing well. We have the same type of BC, mucinous.

Hope everyone is staying safe and healthy.

Pinger - the heavy period should shed the uterine lining but I would plan on a follow up pelvic ultrasound since you had a clean biopsy and you are continuing on the tamoxifen. I would think your GO would have that it the plan as an annual check.

My D&C is Wednesday will be so glad to get it done and determine if I have an issue or not. My MO has already pulled me off the Tamoxifen. I will get my original tumor tested early (at four years not five) to see if I need to try an AI.

Thank you so much ladyc2020 ! My results posted late yesterday and thankfully all benign. I was anticipating some dysplasia but all clear whew! Thankful it won't be a hysterectomy summer.

It will be interesting to see where my post op discussion goes given the level of irritation in my uterus.