Ibrance usage: worth it or not?
Met with oncologist about treating my now ER+/PR- HER - breast cancer on my sacrum. He recommended taking Palbociclib/Ibrance along with Xgeva and Arimidex. Found out that a 21 day supply of Palbociclib sells for $13,000. A 21 day supply for a drug that won't kill the cancer, but stop its growth. Question is: has any one had success with Palbociclib? If so, how long should it be taken beyond 21 days?
Comments
-
21 days/7 off is a cycle. You take until it doesn't work anymore. I was on it for 30 cycles. Pretty easy drug to take, I had to dose reduce to 100mg because 150 was too much for me. Apparently there is funding available in the US, but I can't tell you how to access as I'm in Canada. Perhaps someone will chime in to help you out with that.
-
There is a very long ibrance thread here where you can read about how people are doing on the drug. I suspect people there will also have tips on how to access reduced cost options.
https://community.breastcancer.org/forum/8/topics/...
most of us stay on treatment for as long as it works. When it stops working , we move to the next treatment line, and so on until we run out of treatments.
Cdk4/6 inhibitors like palbociclib have improved survival times for many er+ pts. Pretty groundbreaking drug.
-
Here is the Pfizer Ibrance website: https://www.ibrance.com/?src_code=IBRW10028851&gclid=Cj0KCQiAqbyNBhC2ARIsALDwAsCI6BNxgIJLyisbAVhnrg7ZcO9xvPa4Bf3g6yC50yXu5kjCX9MINBUaAu94EALw_wcB&gclsrc=aw.ds . It has links to financial information on Ibrance. Like Moth said, you need to join us on the Ibrance thread in the stage 4 area. Next week, I think I’ll be starting cycle 22 with Ibrance and I have been NEAD since July of 2020.
-
Lotus- As others have said here, you need to understand that you would be on Ibrance until it stops working and the cancer progresses. Then you go onto another drug. You can get financial assistance for the medicine in the United States. My co-pay was $35 a month for most of my time on the med. Then, toward the end, I was on a different insurance plan and my co-pay for the Ibrance was $0. You get a 21 day supply each month, because you take it for 21 days then do not take it for 7 days out of the month. I was on Ibrance for 4 years. No, it did not "cure" the cancer, but it gave me those 4 years. Now, due to the cancer growing, I am on another medicine. But, Ibrance was well worth it for the 4 years more of life I got.
-
I’ve been on Ibrance and Letrozole for almost 3 years and have never paid a penny for the Ibrance. Pfizer has copay assistance as linked by Cowgal. It’s worked well for me and I hope to stay on it. There are occasional posts about people who are on just the hormone blocker (AI) but most of us take a targeted therapy along with the AI. The PFS with the hormone blocker is found to be lengthened by the targeted therapy. Good luck to you
-
lotus,
Because I have survived progression free* for so long, long before Ibrance was approved, I have only been on AI's. I suspect that when I have progression, Ibrance or Verzenio would be tx options which I would gladly take as at stage IV, the reality is that we stay on treatments as long as they continue working and then move on to something else. Nothing that we currently use will cure mbc, nothing so we just try to get as much time out of a given tx as we can. As for the expense, between insurance and assistance programs from the manufacturer, you should not have to worry about the cost. Take care.
* I am atypical and since the approval of Ibrance, very few mo’s would prescribe an AI only. I once asked about adding Ibrance but my mo asked why would I want to add another drug when the one I was currently taking is keeping things at bay. Good point but again, I am an exceptional responder for reasons unknown. If I were dx’ed today, I would take Ibrance without hesitation.
-
And it’s a pill, much easier for most of us than IV chemo. Yes, there can be side effects, what med doesn’t? Most are tolerable. You would start at 150 mg, maybe drop to 100 or 75 mg. I’m another who has a $0.00 copay for it. I’ve been on it almost 2 years.
-
I just finished cycle #19 of Ibrance. Started at 125 and then dropped to 100 after four cycles, due to low ANC and white blood cell counts. Have never paid a penny. Co-pay is supposedly $75.00, but that is covered by Pfizer. No questions or inquiries into our income. When I read the insurance EOBs, they list the price as anywhere between $14K to $22K per cycle. Yikes!
Categories
- All Categories
- 679 Advocacy and Fund-Raising
- 289 Advocacy
- 68 I've Donated to Breastcancer.org in honor of....
- Test
- 322 Walks, Runs and Fundraising Events for Breastcancer.org
- 5.6K Community Connections
- 282 Middle Age 40-60(ish) Years Old With Breast Cancer
- 53 Australians and New Zealanders Affected by Breast Cancer
- 208 Black Women or Men With Breast Cancer
- 684 Canadians Affected by Breast Cancer
- 1.5K Caring for Someone with Breast cancer
- 455 Caring for Someone with Stage IV or Mets
- 260 High Risk of Recurrence or Second Breast Cancer
- 22 International, Non-English Speakers With Breast Cancer
- 16 Latinas/Hispanics With Breast Cancer
- 189 LGBTQA+ With Breast Cancer
- 152 May Their Memory Live On
- 85 Member Matchup & Virtual Support Meetups
- 375 Members by Location
- 291 Older Than 60 Years Old With Breast Cancer
- 177 Singles With Breast Cancer
- 869 Young With Breast Cancer
- 50.4K Connecting With Others Who Have a Similar Diagnosis
- 204 Breast Cancer with Another Diagnosis or Comorbidity
- 4K DCIS (Ductal Carcinoma In Situ)
- 79 DCIS plus HER2-positive Microinvasion
- 529 Genetic Testing
- 2.2K HER2+ (Positive) Breast Cancer
- 1.5K IBC (Inflammatory Breast Cancer)
- 3.4K IDC (Invasive Ductal Carcinoma)
- 1.5K ILC (Invasive Lobular Carcinoma)
- 999 Just Diagnosed With a Recurrence or Metastasis
- 652 LCIS (Lobular Carcinoma In Situ)
- 193 Less Common Types of Breast Cancer
- 252 Male Breast Cancer
- 86 Mixed Type Breast Cancer
- 3.1K Not Diagnosed With a Recurrence or Metastases but Concerned
- 189 Palliative Therapy/Hospice Care
- 488 Second or Third Breast Cancer
- 1.2K Stage I Breast Cancer
- 313 Stage II Breast Cancer
- 3.8K Stage III Breast Cancer
- 2.5K Triple-Negative Breast Cancer
- 13.1K Day-to-Day Matters
- 132 All things COVID-19 or coronavirus
- 87 BCO Free-Cycle: Give or Trade Items Related to Breast Cancer
- 5.9K Clinical Trials, Research News, Podcasts, and Study Results
- 86 Coping with Holidays, Special Days and Anniversaries
- 828 Employment, Insurance, and Other Financial Issues
- 101 Family and Family Planning Matters
- Family Issues for Those Who Have Breast Cancer
- 26 Furry friends
- 1.8K Humor and Games
- 1.6K Mental Health: Because Cancer Doesn't Just Affect Your Breasts
- 706 Recipe Swap for Healthy Living
- 704 Recommend Your Resources
- 171 Sex & Relationship Matters
- 9 The Political Corner
- 874 Working on Your Fitness
- 4.5K Moving On & Finding Inspiration After Breast Cancer
- 394 Bonded by Breast Cancer
- 3.1K Life After Breast Cancer
- 806 Prayers and Spiritual Support
- 285 Who or What Inspires You?
- 28.7K Not Diagnosed But Concerned
- 1K Benign Breast Conditions
- 2.3K High Risk for Breast Cancer
- 18K Not Diagnosed But Worried
- 7.4K Waiting for Test Results
- 603 Site News and Announcements
- 560 Comments, Suggestions, Feature Requests
- 39 Mod Announcements, Breastcancer.org News, Blog Entries, Podcasts
- 4 Survey, Interview and Participant Requests: Need your Help!
- 61.9K Tests, Treatments & Side Effects
- 586 Alternative Medicine
- 255 Bone Health and Bone Loss
- 11.4K Breast Reconstruction
- 7.9K Chemotherapy - Before, During, and After
- 2.7K Complementary and Holistic Medicine and Treatment
- 775 Diagnosed and Waiting for Test Results
- 7.8K Hormonal Therapy - Before, During, and After
- 50 Immunotherapy - Before, During, and After
- 7.4K Just Diagnosed
- 1.4K Living Without Reconstruction After a Mastectomy
- 5.2K Lymphedema
- 3.6K Managing Side Effects of Breast Cancer and Its Treatment
- 591 Pain
- 3.9K Radiation Therapy - Before, During, and After
- 8.4K Surgery - Before, During, and After
- 109 Welcome to Breastcancer.org
- 98 Acknowledging and honoring our Community
- 11 Info & Resources for New Patients & Members From the Team