CHEK2 gene

BUMP for GrandmaNancy -- can anyone weigh in?

Hi Grandma Nancy,

I"m so sorry this happened again after 18 years. I pray that your upcoming lumpectomy (or mastectomy if you choose) and any additional treatment are successful as your original treatment was. I have the same CHEK2 gene. I am going through radiation now for what I hope will be the only occurrence, but I do understand that gene mutations can make recurrence more likely. I didn't want a mastectomy because I had read a few studies that it could still come back and that lumpectomy was preferred for low grade/stage, but others here will certainly be more of an expert on that than me.

I am learning lately that there is much more to genetics than the existence of a genetic mutation, and that certain lifestyle and external factors can affect our genes (epigenetics) in a way such that the genetic expression is effectively turned on or off. I'm only beginning to learn about the metabolic characteristics of cancer, but it is my understanding from specialists in the field like geneticist/biochemist Dr. Seyfried and others who have done many studies that cancer cells survive by fermenting glucose and glutamine and that some things such as a keto diet (keeping your body in ketosis) and increased exercise/oxygen to the tissues are just a few ways to help make our bodies less hospitable to a new cancer growth.

Also, are you blood type A? If so, you may definitely want to increase digestive enzymes. Please feel free to message me if you'd like any information on enzymes.

I am so sorry for the new occurrence and I hope that you are through treatment as comfortably as possible and on your way to recovery very soon.

Blessings to you,

Esther

Esther01, the research has not shown positive effects of exercise or diet on people with genetic predisposition to breast cancer or even in case of Her2+ BC. Breast cancer is not one single disease and something that might be true for one time doesn't necessarily mean it's true for other types.

GrandmaNancy, my aunt had two different primaries about 20 years apart and is not with us anymore. She wasn't a confirmed BRCA1 case but considering the info we have now she is presumed to have been BRCA1 positive. The genetic counselor told me I also have a very high chance of getting a second primary therefore BMX for me is in the plan.

GrandmaNancy,

Let us know how it goes! That book sounds wonderful. I would love to read it. This has been such a steep learning curve in the past seven months.

Blessings on your weekend,

Esther

I was genetically tested 2 days ago and have BRCA2. My dosage changed and today i had my first infusion with 11 more done on every Friday. I am wondering now which one will get me. I am taking the nausea pills as described. Cutting my hair on Monday at 9am and meeting with the breast surgeon and the Gyno surgeon. With my gene, and my families cancer history, the Brest and women's parts are loved by this cancer gene. If i had a prostate, it would have went there. A little humor will keep us on the road to better health.

Grandma Nancy- I hope it is a diagnosis that can be worked with. Cancer Doctors in 2021 are good. They have not stopped my testing since the 20th of July when i met the team.