Intense PMS after stopping hormonal therapy?

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orangeflower
orangeflower Member Posts: 146
edited June 2021 in Hormonal Therapy - Before, During, and After

I was wondering if anyone else had severe PMS after going off hormonal therapy. I stopped toremifene (similar to tamoxifen) about three weeks ago due to the serious depression and fatigue it was causing, and I'm dealing with my first PMS and period since stopping. I can't believe how intense the symptoms are....Severe irritability and anger, migraines and nausea so bad that they wake me up at night and I'm doubled over throwing up. Normally, I do have emotional symptoms as well as headache and nausea, but not this bad. I've literally blown up at multiple people due to the emotional symptoms I'm having.

I have a call in to my oncologist's office to set an appointment with her about this. I was just wondering if anyone else went through this or have any theories about why the heck this is happening. I thought I would be feeling better by now.

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  • ElaineTherese
    ElaineTherese Member Posts: 3,328
    edited June 2021

    ((Hugs)) orangeflower!!! This sounds like an awful situation. For me, any change in hormones has packed an emotional wallop. Ten days before my period; first trimester of pregnancy; third trimester of pregnancy; post-partum; and of course, hormonal therapy. When I started ovulation suppression (Zoladex) and an aromatase inhibitor (Aromasin), I felt very moody, like I was PMSsed. Since then, I've been on Celexa, which has done the trick. After six years, I have yet to stop OS + AI but I'm hoping that won't be too bad.

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  • orangeflower
    orangeflower Member Posts: 146
    edited June 2021

    Thanks Elaine. I'm going to make an appointment with the psychiatrist to see if anything can be done. I might have to wait this out until my system normalizes.

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