Tamoxifen for 10 yrs total or Switch to AI for the last 5 yrs?

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Hi All!

I'm just about to finish up 5 years of Tamoxifen therapy next month and my MO is fine with me either staying on Tamoxifen for another 5 years or switching to an AI for the last 5 years. And is leaving the decision up to me.

Results from the Atlas trial show good results from staying on Tamoxifen for 10 years. I just know that AI's have been the gold standard for postmenopausal women, which I am now currently.

I've tolerated tamoxifen just fine (brutal hot flashes and occasional night sweats aside). I'm concerned about the bone and joint issues from AI's, and not sure what to do. Looking for some guidance and insight from anyone that's been in this situation and what you decided to do and why.

I just had a bone density test done today, to see where I'm starting before switching therapies. Waiting on those resuts.


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