Abemaciclib Verzenio for Stage IV

That is good to hear SeeQ. She has been on it for approx 6 months.

Nicole,, good luck on your new treatment. You will be in my prayers.

Husband ,, yay on your wife’s scans.

It’s scan time for me. Please keep me in your prayers. I go for CT on Friday and bone scan next week. Tomm i go for labs to check on my counts. Especially my ANC. Uhhhh. The anxiety we get the closer we get to scans. I will be booking a trip to Cancun in the next couple of days. I’m praying my scans are good. Hopefully Verzenio and letrezole doing it’s job. Hugs everyone.

thank you hopeandgrad,,,,,

I plan on going the very ending of may. Yes. I’ve had my first vaccine. I go for my second next week.

Husband and Nicole, thank you for mentioning these side effects. I am on the 150 mg dose and have been for a year. For the most part I have tolerated it well. I have had fatigue constantly and am frustrated most days that I am not more productive. I get things done but it is a constant struggle. I was blaming it on the exemestane but maybe this is the culprit. I have also had strong stomach acid. For the moment it is treatable with daily 20mg Omiperazole but at times it just twinges every time I eat even with the Omiperazole. Nicole, I'm so sorry to see you go. Prayers for you and wishing you much greater success on the Affinitor. You are due for a break!

I have been on Verzenio for about a month. Two major side effects: exhaustion and stomach grumbling. Does anyone elsehave the stomach gurgling? Does anything help? It hurts!

Thanks Hope and Bliss for the kind words and sound advice. After my last post, I was taken off of Verzenio for 3 days, then went on 150 1x/day for three days, then back on 150 2x/day. Did fine the first 3 days and then had terrible diarrhea today. I even pooped in my pants as I was getting up from a nap this afternoon. I apologize if this is TMI.

My MO really wants me on the full dosage but I don't think it will be possible. Will skip my dosage tonight and see what she says tomorrow. I have the 100 mg pills on hand if I can lower the dose.

Thanks Husband for the good news about your wife. Raises my hopes that Verzenio will work for me too!

Hugs, Susan

in your pocket on Wed Bliss! 🙏🙏

Bliss- I pray that it is working! I freaked out every scan for almost 2 years and was stable each time. It was only when we all thought I would be stable for some moretime and ok to delay scans and I was feeling good.....BAM! 2 new tumors, although the 8 original are still quiet. My point only is- it's really hard to know many times. I will keep my hopes up for you

Hope, yes that's me, too. Every time MO was ready to delay scans - bam! I told her she's jinxing me, so stop telling me that!

Nicole, thanks!

Husband, thanks!

so sorry Bliss!! I had hoped it would work for you. Praying for your for next treatment.

Thanks, HopeandGratitude; me, too!

ChathamLady, I've been on it for 3 months.

$12,379.05 - that is the monthly cost of Verzenio 100mg. My co-pay is $50, but I arranged with Lilly to have the same person call me every month after I get my blood test results and ask me questions. By doing this, Lilly is paying my co-pay! They ask if they can contact my Oncologist, and I always say, "No." She runs the entire Oncology dept. and I don't want them pestering her.

I hope your insurance is helping you. Good luck! I started with Ibrance, and my white blood cell count got so low after 3 months and lots of lowering the Ibrance dosage that my oncologist switched me to Verzenio. It has worked out wonderfully for me. My WBC was 4.0 last month. Here is the healthy range: White Blood Cell Count 3.4-10.8%.

I also take Letrozole. I have stage 4 MBC, and am currently immensely lucky because my 6 bone mets (in the usual places) have been inactive for a year. I try to live a happy and stress free life.

I don't know the phone number, but you might start with this:

Phone:

1-800-545-6962

8 a.m. to 6 p.m. ET

Does anyone know why verzenio, like for many drugs, they say never consume crushed or broken tablets? The verzenio tablet is coated with a PVA-PEG coating. It might be because broken or crushed tablets have atmospheric or moisture exposure which could degrade the ingredients, it could be to protect the patient from the drug releasing in the stomach, or to slow the release of the drug. Anyone know for sure? The reason I ask is because my wife would like to switch from 150mg 2x daily to 100mg 2x daily, but if we make the switch, there is no going back. She would like to try the switch to see if it reduces her fatigue. But if it doesn't, she would like to remain on the high dose. Cutting the tablet would be a way to achieve this.

Another option is 2x one day, and 1x next day, to reduce dosage by 25%.

Hi everyone,, so it’s confirmed that treatment is working. I had my appt with MO. Scans show a significant reduction and says treatment is working. I’m so happy. I’m on verzenio / letrezole and zolidex injections. Oh and Zometa every 3 months. Hopefully everyone is doing well. Hugs.

Hopful2 - AWESOME news. Love to hear it! Praying it works for you for a very long time!!!