Prophylactic oophorectomy or not in younger ladies?

I had prophy oophorectomy but when I had it, I was 50 (diagnosed at 49). I was peri-menopausal prior to diagnosis, but oophorectomy threw me into full blown menopause. I had the surgery based on recommendation of my oncologist at time of Dx. I can't say what I would have done if I had been diagnosed in my 30s but if you were my daughter I would say follow your oncologist's suggestion, but if you are not comfortable, then get a second opinion. You can always have the surgery down the road if you are not ready at this time. But that said, listen to your gut feeling/listen to your heart. All the best to you.

hi mango girl, i’m 39, was diagnosed in february of this year. i had the same dilemma but opted to push through with total hysterectomy with bilateral salpingo oophorectomy via laparoscopy, which was done last week. So far, i feel the same. i went thru hot flashes during chemo, i didn’t have any after the procedure. My oncologist didn’t think it was necessary since they can do clinical menopause, i decided out of convenience and wanting to start on Femara. i didn’t want to keep going back to the hospital for shots and i’m quite happy with the size of my family, i have 4 kids .

Hi Mangogirl, I was 34 when diagnosed and ultimately my oncologist recommended I do 3 years of ovarian suppression instead of an oopherectomy. There was not a consensus though among my team of doctors about what was best, it was split between do nothing, oopherectomy and ovarian suppression. Some factors that tipped the scales in favor of just doing the ovarian suppression were a personal history of a tendency towards osteoporosis and a strong family history of heart disease (2 things that are affected by hormone levels). I did 3 years of Lupron injections. The hot flashes were insane and I had some hair thinning but overall it wasn't bad. I finished the Lupron 2 years ago, and it took about 6 months before my cycles came back after stopping. I still have hot flashes but they are very mild and not frequent.

Mangogirl, since tamoxifen prevents estrogen from binding to receptors it would make sense that circulating estrogen would be higher. It isn’t getting “sucked up” by the receptors

MangoGirl, my doctor did not monitor my hormone levels while on the Lupron. And I took Tamoxifen in conjunction with the Lupron.