Xeloda (Capecitabine) OR Paclitaxel (Taxol) ¯\_(ツ)_/¯

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JoK
JoK Member Posts: 2

Asking for a dear friend who has to decide between two treatment options. Quick back story - 17 years ago shehad breast cancer -> radiation was successful. Fast forward 17 yrs and the breast cancer metastasized to lung, then spine, then liver. Radiation has been effective ... but new liver progression has resulted in her onc telling her chemo is next option. Given choice between Xeloda (Capecitabine) or Paclitaxel (Taxol). She is HER2 negative and chemo naive. Besides the difference of oral versus IV - what are your thoughts on which option to pick? I said I'd help her research before making her decision. Thank you kindly for any and all input - much appreciated.

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  • Dharmamum
    Dharmamum Member Posts: 9
    edited November 2019

    Hi,

    If both drugs are equally effective, I would make the decision based on side effects. Both drugs cause fatigue, compromise the immune system and can cause low platelet levels, but the other side effects are quite different. Taxol causes total hair loss & can cause neuropathy which can be permananent. I had IDC diagnosed last January. Among other chemo's I had Taxol and lost all of my hair on my body and had mild neuopathy. Once I developed neuropathy, my oncologist kept my dose at 85% so it never got bad and has resolved completely. My hair has grown back.

    Had a double mastectomy and had residual cancer so I have opted to take Xeloda. I started it today. As I have ulcers am a bit concerned that this drug causes indigestion. It can also cause diarrhea, but am not worried about that at this stage as I spend my life manageing constipation. The hand and foot rash don't sound like much fun, but not everyone gets it.

    If your friend can afford to see a naturopath that specialises in oncology, I would recommend seeing one, as they have a host of tricks to ease the side effects.

    I hope this helpful. Good to your friend on her journey

    Kind Regards,

    Dharmamum

    PS I responded to this post under the assumption that both treatments have equally potential serious side effects (kidney or liver damage etc.), and that is why your friend's oncologist has given her the choice. But not all oncologists are equal so It might be worth her checking with her oncologist that this is the case.

  • JoK
    JoK Member Posts: 2
    edited November 2019

    Thank you very kindly for this detailed response, Dharmamum. I will pass this info along.


    Cheers and all the best to you!

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