Anastrozole or Exemestane? Help me decide.

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Ingerp
Ingerp Member Posts: 2,624
edited November 2019 in Hormonal Therapy - Before, During, and After

I started Anastrozole about a year ago with mostly minimal SEs. At my last check-in with my MO, I brought up the fatigue/brain fog, and she suggested I try Exemestane (not because it's thought to be better in that category, but just because it's different). I can't say I've noticed any changes (bad or good) in my SEs. I did some research on studies comparing the two and of course one tends to have slightly more <insert your negative SE of choice> and the other has slightly more other stuff. As far as I can see, they are equally effective in preventing recurrence. I'll have to decide in a few weeks which one to continue with, but so far it's a coin toss. Any thoughts??

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  • exbrnxgrl
    exbrnxgrl Member Posts: 12,424
    edited November 2019

    I have been on anastrozole, letrozole and currently Exemestane. I believe that they are equally effective but some folks experience fewer se's on one as opposed to the others. I keep switching because of se's, but sadly, they all bother m. I have found ways to cope and since I've been progression free for 8 years, I will stay on one AI or another. I would suggest you make the best choice you can with the info you have. If se's are too bothersome you can always switch. Take car

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