Chemo for Stage 1

Options
Askmissa
Askmissa Member Posts: 76

I’m concerned that I will need chemo as my Ki67 is high and my cancer is progesterone negative. If you had chemo for Stage 1, I’d be curious as to what type and how many rounds you needed

Comments

  • keepthefaith
    keepthefaith Member Posts: 2,156
    edited September 2019

    Askmissa,

    Your MO will probably order the onco-type test, if they haven't already. That will help determine your treatment. My ki67 was on the high end and low PR, but onco-score was 21. It was considered Intermediate. That was before TailorX trial results were out. Now, I probably would've skipped chemo. They also use age as a factor. My MO really left it up to me, but lightly "recommended" it.

    You can see my treatment stats below.

    Best wishes!

  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    Thank you! Yes an oncotype was ordered.How was your chemo? Did you lose your hair with the chemo you had?

  • Pinkpinkturk
    Pinkpinkturk Member Posts: 18
    edited September 2019

    Has bone metastasis been experienced when stage 1a?

  • keepthefaith
    keepthefaith Member Posts: 2,156
    edited September 2019

    Askmissa, yes, most of my hair came out by the end of treatment, including some eyebrows and eyelashes... But, thankfully, it all came back, with the exception of some lashes. If you are concerned, you may want to look into cold-capping. My younger sister had a different chemo 20+ yrs ago, and her hair loss was minimal. You will want to discuss options with your MO. But, who knows? You may be able to skip chemo altogether!:)

  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    keep the faith- Thank you for responding.How long did it take for lashes and hair to grow?

  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    No chemo needed for me, thankfully!

  • keepthefaith
    keepthefaith Member Posts: 2,156
    edited September 2019

    Good for you!!!


  • OnTarget
    OnTarget Member Posts: 447
    edited September 2019

    I'm doing 4 rounds of TC.

    I'm cold capping and still have a full head of hair 6 weeks in, but it is thinning/shedding and there are some balding spots which are hidden.

    I should have been completely bald between day 14 and 18, so I think it is great. Even if more comes out, I've saved a ton.

    I still have eyebrows and eyelashes.

  • Eigna
    Eigna Member Posts: 438
    edited September 2019

    That’s great Askmissa! I’m wondering if I will need but still haven’t done my surgery. I’m 43 with grade 3 and progesterone negative.

  • Beesie
    Beesie Member Posts: 12,240
    edited September 2019

    Askmissa, do you mind sharing your Oncotype score?

    It seems on this board that most of the women with PR-, high Ki-67 cancers end up with scores that do lead to a recommendation to have chemo. It will be encouraging to others, and an interesting data point, to know that this type of pathology doesn't necessarily mean a higher score.

  • Brilee76
    Brilee76 Member Posts: 227
    edited September 2019

    I have type 1b and am about to start 4 rounds of TC. I wasn't going to need chemo but 1 of my nodes came back positive which wasn't expected and my Oncotype came back high risk for recurrence.

  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    My Medical Oncologist is Claudine Issacs at Georgetown University. Oncotype didn't have enough tissue to do my oncotype and Dr. Issac said she wouldn't even want their results. She said that I didn't need chemo and likely didn't even need Tamoxifen, but in 2019 that hasn't been proven yet.


    https://www.medstarhealth.org/doctor/dr-claudine-j-isaacs-md/

    https://www.youtube.com/results?search_query=claudine+issacs

  • SimoneRC
    SimoneRC Member Posts: 419
    edited September 2019

    Hi Askmissa!

    Glad to hear you are moving forward! Looks like you are fairly young and ER+. So glad you love your MO. Personally, I would be hesitant to do only surgery with fairly young, ER+ IDC breast cancer. I know this is just one story, but metastatic disease scares the heck out of me and I did not hesitate to do AI, and would have done Tamoxifen if premenopausal. I was 51 at diagnosis, in great shape and very healthy. My MO, BS and RO (even though I wound up not having radiation) at Johns Hopkins all recommended AI. I was stage 1A, ER+, IDC.

    https://www.baltimoresun.com/health/bs-hs-patient-...

    Just food for thought. It is your life. Maybe check in with another great MO and see if they both agree that your ER+ IDC does not need Tamoxifen.


  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    SimoneRC -

    To clarify, she put me on Tamoxifen which I've begun taking. She just meant that for a 3mm tumor, it may one day be proven that I am already cured and may not have needed the hormone therapy since I had a double mastectomy.

    Andrea :)

  • SimoneRC
    SimoneRC Member Posts: 419
    edited September 2019

    Glad to hear that!

  • Beesie
    Beesie Member Posts: 12,240
    edited September 2019

    Askmissa, with a 3mm tumor, my MO would have said the same as yours, and in fact would have refused to even send for an Oncotype result.

    The average tumor size within the TAILORx study (the study on which the current Oncotype results are based) was 1.75cm, and only 15% of participants had a tumor that was 1cm or smaller. So his position would be that the Oncotype results would be meaningless for someone who had a tumor as tiny as yours. I think he would also agree that it's questionable as to whether or not Tamoxifen is even necessary, simply from a risk vs. benefit standpoint (his research focus being the side effects of breast cancer treatments).

    Good luck with the Tamoxifen - hope you don't experience any significant side effects!

  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    Thank you, Beesie! I was so lucky that my cancer was found so early. I think there will be an increasing number of patients like me in the future as awareness andscreening improves.

Categories