Single Hormone Receptor Positive ie. ER + PR- HER2-

Askmissa
Askmissa Member Posts: 76
edited August 2019 in Hormonal Therapy - Before, During, and After

I wanted to see what treatments are being given to those who have the type of breast cancer that I have: ER+ PR- HER2-. We aren't at as high a risk as triple negative but not as low risk as if we were ER+ and PR+. I was diagnosed in June and on August 19th, I will have having Nipple-Sparing Bilateral Mastectomy with immediate reconstruction with Prepectoral Implants.

· Share on FacebookShare on Twitter

Comments

  • Beesie
    Beesie Member Posts: 12,240
    edited August 2019

    Here are other threads on this same subject that you might find helpful. The first is lengthy, currently 13 pages of posts. The third is about Oncotype scores for those who are ER+/PR-/HER2-.

    https://community.breastcancer.org/forum/137/topics/858729

    https://community.breastcancer.org/forum/96/topics/872099?page=1#post_5414866

    https://community.breastcancer.org/forum/108/topics/872554?page=1#post_5430748


    · Share on FacebookShare on Twitter
  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    Thank you SO much!! :)

    · Share on FacebookShare on Twitter
  • RimRoc
    RimRoc Member Posts: 32
    edited August 2019

    I’m in your situation but about a year ahead. Single mastectomy last summer followed by chemo as my oncotype dx score was about 50. Even tho the pathology came back ER+ PR- HER2-, Oncotype categorized the ER level as negative and hence the high recurrence score. The tumor was very weakly ER+

    I was told there “might” be some benefit from Tamoxifen (even tho I am post- menopause, due to pre-existing arthritis and bone density loss, my onc opted for tamoxifen rather than AI. )

    I’ve been on T for 9 months and I’d describe my SE as “annoying” but not worse. Fatigue, a few hot flashes, way more vaginal secretions than I’d like. Annoying but not awful. Who knows if it will do any good?

    I had DCIS in 2013, didn’t take tamoxifen. Then i had stage 1 cancer in 2018. I get peace of mind knowing that I won’t have to be mad at myself for NOT taking tamoxifen, Ifcancer ever recurs. Pretty weak as reasons go.

    Everyone has to decide for themselves.

    · Share on FacebookShare on Twitter
  • Meow13
    Meow13 Member Posts: 4,859
    edited August 2019

    I am never going to be "mad" about what I did or didn't do. There are no right paths of treatment with BC just statistics.

    · Share on FacebookShare on Twitter
  • Askmissa
    Askmissa Member Posts: 76
    edited September 2019

    Thank you, RimRoc! Very helpful. Do we get our Oncotype after surgery. Is it pretty standard or should I mention to my doctor when I see them before surgery this Monday

    · Share on FacebookShare on Twitter
  • Murfy
    Murfy Member Posts: 342
    edited August 2019

    Wouldn't hurt to ask your doc about wanting it. My sequelae was surgery, a few days later a path report, a week later I visited oncologist who then ordered Oncotype and 3 weeks later....results!

    · Share on FacebookShare on Twitter
  • wanderweg
    wanderweg Member Posts: 549
    edited August 2019

    Askmissa - Many surgeons automatically send a bit of the tumor out for oncotype testing, but I’d check to make sure. Mine fell through the cracks and so there was a many-weeks delay. Turns out it was high enough (38) to need chemo - something both my oncologist and breast surgeon were surprised by. Like RimRoc, I was put on tamoxifen instead of an AI because I already had osteopenia. I take it at night and it actually helps me sleep. I really haven’t had any serious side effects from it.

    · Share on FacebookShare on Twitter
  • DebAL
    DebAL Member Posts: 877
    edited August 2019

    askmissa, mine was sent automatically. I would definitely ask rather than waiting till after your next appt. It just saves you the extra waiting period if its sent later. Best wishes for speedy healing!!

    · Share on FacebookShare on Twitter
  • Cutie
    Cutie Member Posts: 67
    edited August 2019

    Hi All,

    I am single receptor positive but it is PR+/ER-. I haven't found anyone like me yet. I have done chemo which respond very well as Pathology Complete Response, PCR, in my surgery pathology report. I did BMX going flat. Now I need to do radiation and hormone therapy. I checked hormone therapy is mostly for Estrogen blockers and I have estrogen negative. So I am worried about if it is the right treatment. Should I get progesterone blocker etc. Does anyone know on this?

    I am seeing radiation oncologist this week. I am thinking to do only armpit for radiation.


    Cutie

    · Share on FacebookShare on Twitter

Categories