Tamoxifin use for the over 60’s

You might find some really good information in this thread (I know I have):

https://community.breastcancer.org/forum/78/topics/696015?page=994#idx_29797

Well yes, my bone broke and yes from running. Had just gotten back to building my base when this dx hit.

I salute your cycling marathons! Had a bad bike accident as a kid so that's pretty scary to me (silly but there you go). And you didn't sound cavalier at all!

Im 69, 68 last year when I had surgery and radiation. The Dexa scan I had the same day as my mammogram showed full-blown osteoporosis in my hip and osteopenia in my spine. My MO wanted me to take an AI plus Prolia, but there are dental problems with Prolia and I probably need dental work. Due to other medical issues I had to deal with, I didn't want to get into a complicated, multi-drug situation. I was having problems wrapping my head around all of it, so my nice MO looked at me and said "Let's try Tamoxifen." I'm already on a daily aspirin regimen, so she thinks I'm safe from clot problems. I don't have to worry about endometrial cancer (been there, had the hysterectomy in 2008). And my BS said that Tamoxifen actually helps build bone strength. So I took it for four months. The hot flashes were easing off, and the multiple muscle cramps had improved, but I was turning into a shrieking bitch. So I quit in early April. And I remained a shrieking bitch. Maybe that's just me, now. Anyway, I started taking them again early last week, but just one every other day. Oddly, my mood swings seem to have improved very slightly, but I'm still scaring myself (and the poor dog. And husband.) I have an appointment with my MO next month, and I'll discuss it all with her. My BS said I was one of the few patients she's had who admitted stopping the pills, so I've been feeling smugly saintlike since that appointment! 😇

Cassiecanada, I'd suggest checking reputable sources, like this site we're on, before believing what "somebody said." Science matters, not what some random internet person thinks.

I recently completed five years of exemestane and because the BCI showed benefit of continuing hormonal therapy,(7% risk of distant recurrence) I am going (back) on tamoxifen. Not staying on aromatase inhibitor because I've had extensive bone loss (have taken Reclast for the last 2 years which did reverse osteoporosis a little bit). Anyone else go beyond their 5 years of treatment and go back on tamoxifen? I had all sorts of issues on tamoxifen during my first diagnosis but have since had ovaries removed. I'm on a 30ish day holiday of being off everything until switching over. Hot flashes seem to continue, but less frequently. No Estring when on tamoxifen because of estrionic actions noted in above thread. Not sure how many years this is going to last.

I am 61.

My oncotype score is 29 which means 18% chance of recurrence if I take the hormone therapy. Because I already have a little osteoporosis, I will be taking tamoxifen - probably starting the end of this month if I opt out of chemo (most likely will NOT do chemo). I finish radiation on July 23rd (unless I miss a treatment due to machine down, etc).

I will likely start at the lowest dose I can (probably 5 mg) and slowly build up.