i have been on verzenio and the shots now once a month since sept of 2018. i have the typical side effects that they list on the web site as well as what comes on the package. i do have some side effects not listed. i have an over abundance of saliva which causes me to feel like i am drowning. or some time i inhale and the saliva goes down my throat causing me to cough real bad in the middle of the night and during the day. i do not know how to stop this side effect. also i have a big build up of flem in my throat which i am combating it with mucinex, it helps a little. i have the diarrhea i am still trying to figure out what foods make it worse and what foods cause constipation and try to balance the 2, i can still eat but not like i use to. there are days i only able to eat some lunch and a little dinner and other days i m unable to eat. i will become concerned when i have lost a total of 60 lb's. the stuff for anti diarrhea works but if i take as prescribed i than have the constipation, i would much rather have the diarrhea then not. i am still in the early stages of taking my meds. my question to those out there to those who have been taking the verzenio and shots for more than 1 year, does the side effects go away. does anyone else have weird or not mentioned side effects and how are they dealing with. I also take baking soda for my stomach as well as for my kidneys. i take milk thistle for my liver.

THANKYOU

There is an extensive abemaciclib/Verzenio discussion on the stage IV board. I assume both our original poster and softsailor have metastatic disease so should feel free to read and ask questions there. I take a reduced amount of 100mg twice a day and just had a PET scan which showed less tumor activity in several areas of my skeleton. So, the combination with Faslodex injections and Zometa infusion monthly seems to be working.

I use calcium polycarbophil tablets to control the diarrhea, two daily at noon with a big glass of water. The old brand name is FiberCon and you can usually find it in the laxative section! Even a low dose of loperamide (half of an Imodium) was too much - made me feel bloated and very uncomfortable. I could hardly eat or drink.

Interesting that ss has extra phlegm. I feel like my nose is more runny. Guaifenesin is a good choice for her to thin those secretions, along with pushing fluids. As a retired pharmacist, I am a little concerned about how much baking soda she takes. You can quickly get into an electrolyte imbalance. An antacid like Tums would be safer...

I was
diagnosis with MBC on January 14, 2019. 
The needle biopsy of the lymph nodes in my neck supported the
diagnosis.  I was first diagnosed with BC
in 1993 and after a clinical trial study of high doses of Adriamycin and Cytoxan I assumed
I kicked the BC.  Then in 2005, I had my
first recurrence in my chest wall.  Once
again chemo was administered.  Taxotere
and Carboplatin were the drugs of choice with radiation.  Then in June 2005 after these treatments I started
Arimidex (later switching
toFemara).  All was well until I noticed a swelling of sternocleidomastoid
muscle in my neck.  So, here I am with
MBC in 2019 and taking Verzenio 150 mg twice a day with an infusion of Faslodex
once of month. 

Here are the side effects I am experiencing.

· 
Diarrhea—Imodium-causes
constipation ( I’d rather have diarrhea)

· 
Nausea—Zofran and
ginger tea and ginger candy

• Mouth sores including fever
  blisters—using Zovirax
• Loss of appetite—eating
  small meals
• Rash—went away without medication
• Low white cell count
  (tiredness)

The pharmacist assured
me that these side effects will go away in three months.  I see my oncologist next week and I really
want clarification.  I called Lilly to
see if they had a FACT sheet detailing Verzenio side effects and they did not have
any FACT sheet for their drug.  Only
diarrhea is mentioned as the major side effect. 

Wish all
well in this journey.  I fully expect to
continue a fun filled life. 

funshopper,

This is from the Verzenio website. Scroll down to side effects. Is this what you were looking for?

https://www.verzenio.com/verzenio-by-itself/dosing?utm_campaign=verzsem&utm_source=ggl&utm_medium=ppc&utm_content=%7cbr%7cbr-brand%7c43700032970731887%7cp&utm_keyword=verzenio%2bside%2beffects&gclid=cpc05yxxroecfygvzqodcaydnw&gclsrc=ds

There is a Verzenio board for stage IV here with some great information if that applies:

https://community.breastcancer.org/forum/8/topics/861227?page=31#idx_920