Aromatase inhibitors/cholesterol

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Nancy2581
Nancy2581 Member Posts: 1,234
edited February 2019 in Hormonal Therapy - Before, During, and After

Is any one AI better than another in terms of cholesterol level?. I am currently on letrozole and my overall cholesterol jumped from 156 to 196 in the year I've been on letrozole. My HDL ratio to LDL is good though - under 2. Still I don't like how my cholesterol jumped 40 points and worry what will happen over the years I have to take it. So wondering if the other two AI's might be better in terms of cholesterol.

Thanks

Nancy

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  • Totallytubular
    Totallytubular Member Posts: 62
    edited January 2019

    hello. I take Arimidex and am afraid my cholesterol went through the roof.

    working on a couple other side effects before I consider taking the statins.

    what we do to keep the cancer at bay.

    good luck and check in with your doctor.

    Mary

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  • Meow13
    Meow13 Member Posts: 4,859
    edited January 2019

    Do you take fish oil supplement? I find that helps also getting exercise and eating right helps.

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  • Nancy2581
    Nancy2581 Member Posts: 1,234
    edited February 2019

    Yes I take fish oil. Hope it's helping

    Nancy

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  • leftduetostupidmods
    leftduetostupidmods Member Posts: 620
    edited February 2019

    Same here. Cholesterol went through the roof. Managed to get it closer to normal but it took a couple of years after I went off AIs

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  • KBeee
    KBeee Member Posts: 5,109
    edited February 2019

    I am on Letrozole, and my cholesterol increased about 60 points also. I did get it down 20 points, but it's still annoying. My HDL/LDL ration is such that they are not treating it, but it's still frustrating. In my family, cancer kills most people, not heart disease, so I'll live with the high cholesterol to reduce my cancer recurrence risk.

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  • sbelizabeth
    sbelizabeth Member Posts: 2,889
    edited February 2019

    My total cholesterol jumped from 200 to 240 when I started letrozole. Now I'm taking red yeast rice from Costco and it helps some. I'm on the edge of metabolic syndrome and I don't want to start a statin--it can increase the risk of developing type-2 diabetes. What a balancing act this is!

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