Tamoxifin, Endometrial biopsy & Uterine Cancer

live4them... I had cervical stenosis on my first biopsy. He had to cut an opening to get in. I go for another biopsy on the 18th. If this one is benign, the dr says they won't worry about the thickening unless I have spotting. That is the protocol if you read the literature.

What is D & C?

I was on Tamoxifen for about 17 months. Noticed a change in my discharge and some pink discharge in the toilet. To make a long story short, ended up with endometrial cancer. It does happen. Make sure you get any changes checked out. An Endometrial biopsy isn't fun but it did find my cancer. My linning had thickened to 12 mm. Recovering from my hysterectomy and trying to decide if I should switch to an AI or go back to tamoxifen.

Lulubelle I'm glad you followed up and and nipped it in the bud. Praying for your quick recovery.

I had an endometrial biopsy yesterday. Just as painful as I remember it from many years ago. All I had was really light spotting for a couple of days that never happened again, but that was enough for my oncologist to refer me to my gyn. My gyn said that everything looked normal and the lining was thin when she examined me. She said she's never seen someone get endometrial cancer from Tamoxifen, and she was the head of Ob/Gyn for a while. I'm not worried at all, she put my mind at ease. I should have results by the end of the week.

I was on Tamoxifen for about 25 months. Like Lulubelle I too notice some pink discharge in the toilet. After a lot of checks, I was diagnosed endometrial cancers a week ago. I am premenopausal. I still have my period but it's irregular. I had my endometrial lining checked regularly and never over 1cm. My doctor said it would be OK under 1cm. But I got the cancer!!! Tamoxifen induced endometrial cancer does happen.

I had MRI yesterday to check endometrial cancer stage, should wait till Moday for the result,so scared.

Anyone on this thread know if your uterus goes back to normal on its own after thickening on Tamoxifen? Thanks

Hi all - I am a 8 year, Stage III, survivor on Tamoxifen for close to the same. Tried the AI couldn't deal with the bone pain. I have been spotting/light bleeding now for a few months. The GYN is suggesting an untrasound and biopsy. I too, like everyone else am tired of being biopsied! Do they need to biopsy you before a full hysterectomy? I am ready to loose the girl parts. I still have my breasts and in hindsight wish I would have gone for a double mastectomy too. Too many tests!

I finished with Tamoxifen in 2013, after 2 1/2 years, and then switched to an AI for the same length of time. Two years ago, I had some light vaginal bleeding, and my OBGYN did a uterine biopsy, which was negative. The same thing happened last year, spotting, biopsy, negative results. I asked him about the possibility of a hysterectomy, since I am in my late fifties, and I certainly don't need a uterus anymore, but he felt that the risk of surgery didn't outweigh the benefits. So, here we are a year later, and once again, I am having some light bleeding. I don't even want to go to the doctor, since it doesn't seem to be anything to be concerned about. I'm starting to think that it is something environmental, since it seems to happen around the same time every year. I'm tired of biopsies that show nothing, I've decided to take a break and take my chances.

I have had 2 endometrial biopsies, the first one was not too bad, my doctor had me take two Advil prior to my appointment. It was over with quickly and I bled lightly after the procedure was over, results were benign. The second biopsy was also benign, however, I bled very heavily for over a week after the procedure. I ended up having a DNC last February due to uterine polyps, which was also benign. My doctor told me that biopsies are good for one year, so not to panic if I have post menopausal bleeding but to notify her if this occurs and we will definitely investigate. I have been taking Tamoxifen for almost two years, I do worry about the possibility of uterine cancer and if I keep having problems will probably elect to have a hysterectomy, my doctor told me that she would perform the surgery when ever I am ready, unless cancer is found, then immediately. It is good to read that endometrial cancer is rare, but I do wonder if this is true for the post menopausal woman.

Thehysterectomy was the best surgery I ever had. I should have done it years earlier.

An update..

I don't often log on to this site anymore, it's been a long time since diagnosis and treatment, and I had forgotten that this thread was one of my Favorite topics. But, I had some free time and decided to have a look, and lo and behold, there was a new post on this thread. So, I thought that I would share a little of what happened since my last post. The gyno who was treating me retired, and since I was having "periods" again, I asked to see his replacement, who happens to be a younger woman, very personable and capable, I trusted her from the first time I saw her. When we spoke during my appointment, and she read my files, she was shocked that the other doctor didn't take it more seriously. So, she suggested a D&C, and when she performed the procedure, it turned out that there was a very large uterine polyp, which she removed. It's been almost 18 months, and I haven't had any bleeding or spotting since. Obviously that was the issue. I was frustrated that the first gyno wasn't more proactive, but I'm glad that the situation has been dealt with. I just wanted to write this to let people know that it's not always the worst case scenario.

Take care everyone!

• Hi cassiecanada, I am postmenopausal and had my D&C last month. My GYN was concerned my lining was too thick and the biopsy in the office didn't give her enough tissue. I did have a large fibroid blocking the way. This fibroid I probably had for years and the Tamoxifen started to feed it some estrogen. When I had the D&C they found my lining was within normal limits and that the fibroid was causing the ultrasound to give a false reading. They were able to remove the fibroid. The radiologist called it a polyp, but my Gyn said it was a fibroid and that radiology always use that term. The biopsy were negative!! My Gyn and Oncologist said they would only be concerned if I started having symptoms of bleeding/spotting because Tamoxifen is known to thicken the lining. My other question was concerning ovarian cancer. They felt I wasn't at risk because I didn't have any family history. There is always something to be worried about........