Announcing the Global Challenge to Prevent Breast Cancer

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CBCRP-Nick
CBCRP-Nick Member Posts: 4
edited June 2019 in Advocacy

Dear Forum Members,

I work for the California Breast Cancer Research Program (CBCRP), and I'm excited to announce that last week we launched the Global Challenge to Prevent Breast Cancer to encourage researchers and advocates to share transformative primary prevention ideas.

You can view the challenge at ToPreventBreastCancer.org.

This is a tremendous opportunity to change the trajectory of breast cancer research. Winners will influence $15 million in grant funding to be disseminated by CBCRP over the next five years, get a cash prize, receive feedback on their idea, and have the opportunity to present it to prominent leaders in the field.

As members of this forum, I thought you might be interested in applying. We're looking for both researchers and non-researchers alike to share breakthrough ideas.

Applications are due January 7, 2019. Two grand prize winners will receive $5,000 cash prizes.

Please consider applying and help me spread the word. Thank you. I'm happy to answer any questions you may have as well.

Sincerely,

Nick Anthis
Global Challenge to Prevent Breast Cancer
ToPreventBreastCancer.org
Challenge@CABreastCancer.org

--
Nicholas J. Anthis, DPhil
Program Officer, California Breast Cancer Research Program
University of California Office of the President
CABreastCancer.org

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Comments

  • fredntan
    fredntan Member Posts: 1,821
    edited September 2018

    This sounds interesting. I am stage 4 as you can see.

    What if I did study to see if baby aspirin prevented BC? or something like that. I used to be a nurse. I have been in a clinical trial. I do have a lot of free time on my hands. Is there any guidance for non researchers? There are a lot of supplements people like me take to keep BC away. Like Turmeric, Frankinsence etc. Does the grant money have to go towards prevention?

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  • Meow13
    Meow13 Member Posts: 4,859
    edited September 2018

    I am not sure if we can do things to prevent BC when we don't know what caused it in the first place. The only thing you can do is take care of yourself to be as healthy as possible.

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  • WC3
    WC3 Member Posts: 1,540
    edited September 2018

    Some questions:

    Do traditional Japanese and Korean diets result in lower breast cancer rates?

    Why does Mongolia have low rates of breast cancer despite a diet that consists almost exclusively of meat and dairy? Is it really lower or is it under reported?

    How much estrogen is in American dairy products compared to Mongolian dairy products, and is there a relationship between estrogen content and breast cancer?

    Same question as above for epidermal growth factor and IGF-1.

    Is there a way to lower breast density other than taking tamoxifen?

    Why does Belgium have such high breast cancer rates?


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  • AliceBastable
    AliceBastable Member Posts: 3,461
    edited September 2018

    Just from reading different boards here, it seems there are so many different kinds of breast cancer - hormone positive, hormone negative, triple negative, in situ, invasive, ductal, lobular, and many variations of each of those, not to mention the rarer types. So it seems unlikely that a prevention that's one-size-fits-all will be found, when the types of cancer and treatments vary so widely.

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  • WC3
    WC3 Member Posts: 1,540
    edited September 2018

    Another question:

    Egg consumption is associated with increased mortality via an increase in rates of metastasis in prostate cancer. High levels of choline and the fact that prostate cancer cells have an abnormal choline metabolism are implicated in this. Breast cancer cells also have an abnormal choline metabolism so does the same hold true for breast cancer?


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  • ksusan
    ksusan Member Posts: 4,505
    edited September 2018

    ...or are there genetic differences between groups of people that affect BC rates? We know that CYP450 metabolism differs between Euro and Asian people.

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  • Meow13
    Meow13 Member Posts: 4,859
    edited September 2018

    I was told by multiple physicians my radiologist, my breast cancer surgeon and my top BC oncologist that why I got BC is unknown and nothing in my genetic makeup or lifestyle points to anything. Plain and simple totally unknown for my case. So there must be other absolute knowns out there for other cases. I applaud them if they can prevent this disease in anyone I just don't see it. Preventing BC doubt it reducing risks maybe.

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  • DATNY
    DATNY Member Posts: 358
    edited October 2018

    Wc3 regarding Mongolian....or Inuit....or similar. These populations escape immunomodulation by heavily "treating" with anti-inflammators and antibiotics every little cold and flu they get; perhaps they get less vaccines too. I think they fight infections mostly by waiting to pass, at most using some supplements but not western medicine which strongly interfere with immune system function.




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  • CBCRP-Nick
    CBCRP-Nick Member Posts: 4
    edited October 2018

    > Sep 28, 2018 05:35PM fredntan wrote:

    >> This sounds interesting. I am stage 4 as you can see.

    >> What if I did study to see if baby aspirin prevented BC? or something like that. I used to be a nurse. I have been in a clinical trial. I do have a lot of free time on my hands. Is there any guidance for non researchers? There are a lot of supplements people like me take to keep BC away. Like Turmeric, Frankinsence etc. Does the grant money have to go towards prevention

    fredntan - The Global Challenge is unique because applicants are just being asked to propose ideas for research, but not conduct the research themselves. You could propose an idea that could be carried out by anyone. We are very interested in ideas from both researchers and non-researchers, and we will have separate prizes for each category.

    I appreciate all of the ideas, and I encourage folks to check out the website for the Global Challenge (ToPreventBreastCancer.org) and consider submitting some of your ideas to the Challenge!

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  • WC3
    WC3 Member Posts: 1,540
    edited October 2018

    I think a lot of people here would like some more definitive dietary studies because diet is an easy to control for variable.

    Also, it would be nice if there were studies better defining the role of progesterone and progestins in cancer development and inhibition. There were some planned clinical trials but I don't know if they ever got off the ground.


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  • topdubu
    topdubu Member Posts: 23
    edited June 2019

    Just returned from my second Mongolia trip. The meat thing is largely a myth these days. I eat significantly more meat here in the US. True, they have meat with most meals but it is like using hamburger helper in that they use lots of rice, pasta and bread to stretch the meat. In the far west, cheese and yogurt from goats, sheep and yak is abundant. In the cities, meat is becoming expensive as prices are being bid up principally due to surging Chinese consumption.

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