99% Er and Pr Positive

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Walden1
Walden1 Member Posts: 202
edited September 2018 in Hormonal Therapy - Before, During, and After

This maybe obvious, but does anyone know if hormonal therapy is more effective when your cancer has is highlyEr and Pr %? Also, do they know if the cancer cells actually die or just go dormant when taking hormonal therapy

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  • Lula73
    Lula73 Member Posts: 1,824
    edited September 2018

    yes the higher the sensitivity percentage, the more effective the anti-hormonal therapy is. The therapy starves any remaining cancer cells of estrogen leading to eventual cell death. However, some cancers are more aggressive and the therapy can just slow it down, but not eradicate it. Additionally those cancers that are less sensitive to ER may not sufficiently starve with antihormone therapy and the cancer has better chance of coming back.

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  • letsgogolf
    letsgogolf Member Posts: 263
    edited September 2018

    My ER was 100% and PR was 99.89%. All of the doctors that I have seen have told me that the anti-hormone drugs will be especially effective for me due to my high numbers. I just hope they are right.


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  • beach2beach
    beach2beach Member Posts: 996
    edited September 2018

    That is what they say. Even if one is weakly positive they still often recommend it to hopefully knock the odds down even more.

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  • Walden1
    Walden1 Member Posts: 202
    edited September 2018

    Thanks so much for your response. Very good to hear! My cancer is 99% Er and Pr positive. Mydoctors have always said hormone therapy is particularly important for me, but have never explained why in much detail.

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  • Meow13
    Meow13 Member Posts: 4,859
    edited September 2018

    My oncologist said they die, AI drugs would kill them.

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