Arimidex AND Raloxifene?
My new gyn prefers Raloxifene over Fosamax. She decided to prescribe it because of the side effects I've been having with Fosamax. After doing some research, I realized Raloxifene and Tamoxifen are similar (SERM) drugs. Can I take both an AI and Raloxifene at the same time? I have sent a message to my MO to check with him but it could be a couple days before I hear back. I've been taking this for about a week and would like to know now if I should stop. TIA!
Comments
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>>Can I take both an AI and Raloxifene at the same time?<<
You should not.
"Estrogen receptor modulators (raloxifene and tamoxifen) also have antiresorptive properties. However, in one large trial, combining an SERM and an aromatase inhibitor blunted the reduction in breast cancer recurrence compared with an aromatase inhibitor alone. Therefore, SERMs should not be used for the prevention of osteoporosis in women who are taking an aromatase inhibitor.130"
Source: http://ascopubs.org/doi/full/10.1200/JCO.2015.64.3809
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(02)09088-8/fulltext
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