This is the big dilemma for me with drugs. My cholesteral is high. I had (odd rare) ovarian cancer with large volume ascites that resolved with surgery, but still...I was very sick and almost died. Right after that I was diagnosed with LCIS. They wanted me to take AIs to prevent breast cancer. This makes cholesteral worse. They wanted me to take statins, which can cause liver problems, right after I had a very, very unhappy liver with ascites. One drug will lead to another & another..

cp418 - thank you for starting this thread. It is interesting that the article in Cure was published 10 years after the original study article which you also kind enough to post. I found the Cure article fascinating - personal interest: just starting statins, reading while waiting to be seen in oncologist's office AND THEN WHAT??? I assumed that she would raise the question of statins and cancer recurrence with her oncologist and I wanted to to know what she/he said!!!!! and then I realized (duh!) this is a magazine meant to be read in an oncologist's office. the message is ask your oncologist - WE aren't stating an opinion. So thank you Wrenn for doing additional research on this question.

At first glance, this study appears to offer evidence to the contrary. At closer glance, it makes me angry. If I read it correctly, it talks about how this study showed that women with higher cholesterol had lower rates of cancer. They attributed this to ...... get this....... the fact that women with high cholesterol probably took statins, and the statins likely lowered the cancer risk. 😡

No direct study of that.

https://www.sciencedaily.com/releases/2017/08/170828093810.htm

Thank you for starting this thread. The timing is impeccable. My cholesterol jumped 60 points this year thanks to Letrozole. I am thankful Letrozole has kept the cancer away so far, but the cholesterol annoys me since I eat very healthy and exercise daily

Here’s more recent information.

Statins slash risk of death by cancer by up to 50% reveal major studies | Daily Mail Online

http://www.dailymail.co.uk/health/article-3108313/...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716320/#!po=23.1481

That article does summarize many potential benefits of statins, but also some long term cautions. It sure would be nice to have a randomized study since many of these studies are retrospective or very small. It would be so easy, but since statins are so cheap, it would likely be like studying aspirin. No one wants to do it if there aren't bigbucks in it!!!!

So I’m wondering why they don’t just say if your cholesterol results are all in normal range, you have a 40% betterchance of not getting cancer? It can’t be better to have high cholesterol, ldl, and trigliserides that are controlled by statins, can it?

I tried to take statins once a long time ago, I got the muscle pain side effects so I quit them. I finally learned (too late) how to keep my cholesterol in line by changing my diet but according to my BS my cancer had been growing slowing for 20 years. Yes that's what he said. I'm hoping since my cholesterol is normal now that I'm getting the 40% benefit against recurrence.

So wrenn, are the statins causing a problem for you? Why don't you want to stay on them?

My cholesterol seems to be controlled with diet and exercise but there are people that need the statins. I find the doctors tend to over prescribe.