Stressed out of my mind!

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Courtz
Courtz Member Posts: 11

Hey

I am 31yo in July and in early January I noticed a really large hard lump under my nipple and areola, so I asked my specialist physician (I am type 1 diabetic) for a referral to have it scanned. The Radiologist did a sonar, followed by a mammogram and gave me a BI-RAD of 4B in the suspicious range, and did a US guided core biopsy. He wasn't all that happy with the 4 samples he too, as they were small, because he battled to get a sample. The lump is as hard as a marble, so he had to put his full body weight into getting the needle in, then it got stuck as he pulled it out. this happened all 4 times. My Specialist sent me the results 2 days later, and everything came back as benign.

I sent the results to a breast specialist I had previously seen in 2011 (for my extremely dense diabetic breasts) and she immediately responded that she wanted to see me the next afternoon.

She said it is most likely a Diabetic Mastopathy, but that she would review it with her radiology and pathology board the following Monday and decide from there. The Monday I received a call saying that she had booked me for a repeat core biopsy on the Tuesday.

I got those results yesterday, basically stating that there is an abnormality, but they don't know what it it is... and the report reads as follows:

"Histopathology:

Clinical history:

The patient is a 30 year old female with a retroareolar mass on the right side. This is categorised as BIRADS 5. (YES! THIS HAS NOW GONE UP!) She has a strong familial history of cancer

Macroscopy:

The specimen comprises two needle cores measuring 14mm each.

Microscopy:

Histological examination shows densely sclerotic fibrous connect tissue within which there are single-lying foamy cells with mildly atypical nuclei. There is patchy mononuclear inflammation. The appearances of this lesion can be seen on the microphotograph. (Obviously not scanning that in to show)

Immunohistochemistry:

In the presence of an adequate and positive set of controls, the following results have been obtained:

1. MNF116 - negative

2. AE1/3 - negative

3. Oestrogen receptors - negative (016)

4. Progesterone receptors - negative (010)

5. Her2 - 0 (negative)

6. E-cadherin - negative

7. CD31 - negative

8. S100 - negative

9. CD68 - positive

10. Desimin - positive

11. CD3C - negative

12. C2-C3 - positive, T-cell lymphocyte present

13. CD20 - positive, scattered B-cell lymphocytes present

14. SMA - positive, is MSA weakly possitive

Comment:

The features noted are those of a non-specific fibroinflammatory response with a reactive myofibroblatic cell proliferation nu NO definitive evidence of malignancy. There are histiocytes present and no infective pathogen. This may represent a fibroinflammatory response, chronic mastitis or an area adjacent to a ruptured lesion. No definitive malignancy is noted in the sections examined. Please correlate with the radiology and decide whether further specimen or excisional biopsy of the lesion is necessary. "

So now she has ordered a specialized MRI and an excisional biopsy to remove the entire lump on Monday morning and I must admit, as calm and rational as I am trying to be and telling myself everything is fine, I am worried.

Has anyone else had a similar lab work up?

Comments

  • mustlovepoodles
    mustlovepoodles Member Posts: 2,825
    edited February 2018

    Perhaps djmammo will come along and more thorougnly interpret this for you, but it looks to me like there has been no cancer found. I'm glad you're having it taken out, since it does seem to be a little weird. Hopefully, nothing new will show up.

  • gb2115
    gb2115 Member Posts: 1,894
    edited February 2018

    These look like really good results. But definitely good that they are going to take it out to make sure. But try to rest easy. After all, they could have said it's cancer and they didn't! :-)

  • Courtz
    Courtz Member Posts: 11
    edited March 2018

    Thanks Ladies :)

    I spent a LOT of time Googling and reading through posts on here, so I am feeling tons calmer and and way more together as everything that I found leans more towards an Inflammatory myofibroblastic breast tumor or Diabetic mastopathy that are both usually considered to be benign conditions. Also the part were they said NO definitive malignancy, makes me feel a lot more confident that everything is fine and that my initial freak outs (yes, I had two, with the first while waiting for the first biopsy results and the second after the results of the second one came out) are more unfounded and neurotic than anything else.

    Thank you so much for the support and kind words, my hat goes off to all you crazy, strong, resilient women!

    Will pop a reply post when I know what's potting!

    xxx

  • Courtz
    Courtz Member Posts: 11
    edited March 2018

    And it's official! I have a benign diagnosis! So the official diagnosis is sclerosing lymphocytic lobulitis, or diabetic mastopathy, however my BS said she would have taken it out anyway from the MRI as even there it looked highly suspicious and even once she took it out, she waited for the pathology to make sure it wasn't an ugly! So overall, great news! :) Thank you so much for the support!

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