Neoadjuvant chemo Navelbine/Gemzar

Misstic · January 2018

I come back from MO. He told me that my Stage IIIC recurrence needs the following neoadjuvant chemo for the next 6 months: Navelbine/Gemzar. I navigated the forum and see that these chemo are only applied to Stage IV BC. I am freaking out about what this mean. I had previously a petscan (no mets), my CA 15-3 is 12 (as it always have been), and the CT scan shows 5 lumps in my breast (12 + 6 + 5 + 3 +2 mm) + 1 node (6 mm) in my armpit.

I had severe neuropathy from my Taxol chemo in 2014 (I recovered pretty well easaly) + allergy. MO told me I can never get a new taxane chemo for the rest of my life...

Anyone who experienced a such regimen at Stage III?

beauz · February 2018

Hi Misstic- probably because you had a severe reaction to taxol. A lot of us with stage III BC are or have been on Xeloda which used to be a chemo for stage IV BC. I would ask my MO for further information. Best wishes to you.

Misstic · February 2018

Thank you @beauz.

Actually, first he said Xeloda, Endoxan and Methotrexate but when we discuss about the Petscan which showed that I have a problem in the colon and need a colonoscopy to assess it is only diverticulum, he switched immediately to Navelbine/Gemzar...

beauz · February 2018

Xeloda is also a chemo for bowel cancer… it doesn't matter what chemo you have as long as it works. Are you planning to have surgery and radiation after chemo? Take it easy.

Misstic · February 2018

Yes, the doctors plan to do surgery and radiation after chemo.

I went to a second hospital for a second opinion about my case.

beauz · February 2018

Misstic- I am glad to hear you had a second opinion. I just remembered that a lot of people here talked about going on Ibrance soon after finishing their main treatments.

beauz · February 2018

Misstic- I am glad to hear you had a second opinion. I just remembered that a lot of people here talked about going on Ibrance soon after finishing their main treatments.

Misstic · March 2018

Here is some news about my regimen.

Like for Taxol, I had an allergic reaction to this chemo: itching spots on my cleavage, short breath and allergic sinusitis (causing eyes swelling)... My MO feared an anaphylactic shock so he tried one round with only Gemzar. It seems that the sinusitis is caused by the Gemzar and the other symptoms by the Navelbine.

I see him next friday. I will see what he decides for the rest of the treatment.

sbelizabeth · March 2018

I had Xeloda and Navelbine as adjuvant chemo. It was started when I was close to the end of my radiation treatments.

Misstic · March 2018

Did you get a recurrence like me @sbelizabeth ?

I don't see it in your profil.

Misstic · September 2018

A feedback about this uncommon regimen. It works perfectly on me: I started my journey with 5 tumors and 1 lymph node. I finished my chemo and had a mastectomy + 7 lymph nodes off: they found absolutely nothing but scar tissue.

In addition to this regimen, I did a keto diet and had CBD (1 mg per kilo).

I am officially NED but I still have to do radiotherapy and 10 years of new type of hormonal therapy (previously on Tamoxifen).

beauz · September 2018

Woo! Well done! Very happy for you! Good luck with the rest of treatment.

Neoadjuvant chemo Navelbine/Gemzar

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