Does anyone request a hormone test before starting Arimidex?

Options
annwill64
annwill64 Member Posts: 16

Hello, I am about to start my radiation, but I am also thinking about the endocrine therapy, Arimidex. Does anyone have a hormone test done before they start this. If it is a estrogen blocker, shouldn't we know if I still have a lot of estrogen in my system. I know my tumor was estrogen positive but it is my understanding that this could have been forming for years as I was going thru menopause. I haven't had a period for nearly 4 years. If anyone has any information on this I would appreciate the post. Thank you!!!

Comments

  • Icietla
    Icietla Member Posts: 1,265
    edited October 2017

    Hi annwill64. The medicine is not exactly an estrogen blocker -- it does not block estrogen already there, but it inhibits the body's production of estrogen. Ovaries are not the only source of estrogen. See the first paragraph of ChiSandy's post here__

    https://community.breastcancer.org/forum/96/topics/854966?page=1#post_4963365

  • Legomaster225
    Legomaster225 Member Posts: 672
    edited October 2017

    I had an estradiol and FSH test. My periods were regular prior to chemo but I have now not had a period since beginning of February. Both tests indicated menopause but my dr wants to retest in January to be sure it is menopause and not just the effects of chemo and other treatments. I will start on Tamoxifen next week and we will revisit this and potentially switch to an AI next year. You could always ask for the blood tests if you want to know. I am not sure if there are other tests in addition to my basic ones

  • dtad
    dtad Member Posts: 2,323
    edited October 2017

    annwill64...IMO having your hormones tested before, during and after anti hormone treatment should be a must. Unfortunately a lot of MOS do not do it. You may have to rely on your gynecologist, PCP or naturopathic doc to do it. Good luck and keep us posted.

  • Bosombuddy101
    Bosombuddy101 Member Posts: 182
    edited October 2017

    Icietla,

    Thank-you for that link! So, wouldn't it make more sense to test the levels of androgens circulating in one's system and figure out ways of reducing these levels? Is there a drug for that? I've read that losing weight and eating a diet low in sugars and fats and high in phytoestrogens such as flax seed can reduce androgen levels.

  • Icietla
    Icietla Member Posts: 1,265
    edited October 2017

    You are welcome. I have no background in chemistry, but I would suspect that phytoestrogens would have estrogenic effects. I do not know of any better medicines for us than those our Oncologists recommend for our own cases.

    My AI treatment has been easy -- it is just one little pill, once a day, and also the Calcium w/ Vitamin D tablets I had already been taking anyway for fifteen years. I hope to continue my AI treatment for fifty more years.

  • LeesaD
    LeesaD Member Posts: 383
    edited October 2017
    My MO tested my estrogen levels prior to starting AI's (anastrozole) as I was pre menopausal and suppressing my ovaries with Zoladex shots. He wanted to make sure I was suppressed or else AI's would not work. My estrogen levels were virtually undetectable he said. I started anastrozole about five weeks ago. I saw MO last Friday first time since starting AI's and he tested my estrogen levels again and results still lowest detectable estrogen so all good.
  • annwill64
    annwill64 Member Posts: 16
    edited October 2017

    I guess I have a lot to learn and understand about the endocrine therapy, If your estrogen level is already low then why do you go on the meds. Anyway are you experiencing any side effects. Hope you are doing well!

    Thanks for you reply!

  • annwill64
    annwill64 Member Posts: 16
    edited October 2017

    So you are not doing radiation or endocrine therapy? I am with you about having tests to see what our levels are! Hope you are doing well!

  • muska
    muska Member Posts: 1,195
    edited October 2017

    Ann, if you have been in menopause for four years you don't need hormone test before starting AI. And being in menopause / having low estrogen levels is not the same as taking AIs

  • dtad
    dtad Member Posts: 2,323
    edited October 2017

    musk..IMO you should have hormone testing before, during and after anti hormone therapy. Good luck to all.

  • grandma3X
    grandma3X Member Posts: 759
    edited October 2017

    my PCP ordered the lab test for estrogens after I had been on AIs for a couple of months. I asked him to do it. When I found that my estradiol was still elevated, I asked my MO why. He was upset that I had even asked for the test and said that they didn't mean anything. Anyway, I got him to prescribe the name brand Femara instead of the genetic I had been taking. After 6 weeks on the name brand, my estradiol had fallen to undetectable levels. That made me feel better, but I know not to give those test results to my MO 😊 I just had my ovaries removed so will test again in a few weeks. Even though I went through menopause several years ago, I read that there may be residual production of estrogens after menopause. Just FYI, if your doctors won't order the test, you can get the lab order through Life Extension. They send you the order and you just take it to LabCorp to have the test done. I get total estrogens and a separate high sensitivity test for estradiol. Together they cost about $100 out of pocket.
  • bevin
    bevin Member Posts: 1,902
    edited October 2017

    They checked all my hormone levels before I started the AI's  . I was young so they were checking to see my estrogen levels pre use and then once I was on it a year later.  It gave a good gauge as to if I needed my ovaries removed or not. I was glad they checked my levels and we saw a huge decreese once on the AI ...

  • LittBelt
    LittBelt Member Posts: 6
    edited December 2017

    hi all, I am on Arimidex for a month now and so far not much side effects other than low energy, i was prescribed calcium w/ vit D too but have not been taking it regularly coz I find it too big lol...i am not a fan of huge tablets/capsules coz it kinda make me throw up...so I may just opt to di the Prolia injection every 6months to save my bone mas

  • chronicpain
    chronicpain Member Posts: 385
    edited December 2017

    LittBelt, you cannot officially take prolia unless you are also on adequate calcium and vitamin D ( vitamin D to target a 25-OH level measured by your doctor to be at least over 30 ng/dl and calcium either from diet or supplements to provide between 1.2 and 1.5 grams elemental calcium per day in divided doses.). You need the calcium as a building block for bone (and to prevent acute hypocalcemia cramps or even seizures from prolia) and vitamin D helps absorb the calcium

    If the pills are too big, you can get little gelcaps of vitamin D3 (cholecalciferol) and take one 2000-5000 units/day , depending on your obesity level and absorption, or even a little gel cap by prescription for once a week vitamin D2 ( ergocalciferol) 50,000 units ( not the same as D3 so units are different). Check with a doctor who understands prolia, and it may not be your primary care, might need an endocrinologist.


    You can get calcium from diet (e.g., 3-4 cups of lean milk a day or 3-4 ounzes lean cheese, or 3 yoghurts), spaced out, or take chewable calcium ( e.g., if you are not on acid blockers you can take product called viactiv calcium carbonate chewy caramels or chocolates 1 twice a day with food, or if you are on acid blockers then "chewy bites" calcium citrate (come in different flavors) twice a day, to provide 500mg elemental calcium each to supplement diet if you do not like foods with calcium

    Available on amazon or in drugstores, chewy calcium

  • annwill64
    annwill64 Member Posts: 16
    edited January 2018

    Good Morning! I did have my estrogen checked by my oncologist at Dec. 14th and it was very low. She did explain to me that our bodies not only make estrogen from our ovaries it can be converted from our adrenaline glands. So I prayed and got my Armidex prescription and still couldn't feel at peace about taking it, especially knowing that there are natural estrogen blockers. So I ordered DIM which I have researched and even heard many ladies on this thread have used. So that is my plan, 100 mg a day, cutting my sugar out, increasing my fruit and vegetable intake and praying like crazy that I don't have a reoccurrence. Just felt like I should share, maybe this will help someone. What I really hope is that 5 years from now I will be sharing again, CANCER FREE!! Praying peace, joy, love and good health in 2018!!!

  • ChemicalWorld
    ChemicalWorld Member Posts: 172
    edited January 2018

    The only time I had a hormone test was a few years after not having a period, post-chemo, when all my doctors were assuming I was in menopause from the chemo (I had two periods post-chemo, months and months apart and had not had one for over a year I think at that point). I was on Tamoxifen at the time. Anyway, despite all those assumptions, I was still producing plenty of estrogen and very much not in menopause. Which is why I'm now on Lupron shots.

    No hormone tests in the couple of years since, again they are assuming this works, which doesn't fill me with confidence, given that history, and with that assumption, I am also now on Arimidex.

    I hear that hormone tests can be unreliable when it comes to menopause, as levels can fluctuate. Anyway, long story short, I didn't have one pre-Arimidex.

  • dtad
    dtad Member Posts: 2,323
    edited January 2018

    anwill64....just want to let you know I'm also taking DIM in leu of an aromatase inhibitor. Please join us in your he alternative thread and a few other appropriate threads. Good luck. Happy New Year

  • annwill64
    annwill64 Member Posts: 16
    edited January 2018

    Hello, tried to send you a message about the alternative threads for those of us using DIM, please send me that thread. Thank you!

  • dtad
    dtad Member Posts: 2,323
    edited January 2018

    The alternative thread, the threads titled walking away from aromatase inhibitors and a thread titled my right to no treatment. Not exact wording, but close

  • annwill64
    annwill64 Member Posts: 16
    edited January 2018

    Thank you!!! Reading these threads and I do feel encouraged! I have been taking DIM since Jan. 1st I have woke up each morning with a bad headache, which I do read can be a side effect. Hoping that it does subside, anyone else have headaches from DIM. I am taking 100mg. each day.

Categories