Can you please help me understand my path report

Motherofall6
Motherofall6 Member Posts: 65
edited November 2017 in Stage I Breast Cancer

Invasive Breast Cancer

Staging According to American Joint Committee on

Cancer Staging Manual 7th Edition

Macroscopic:

Specimen: Partial Breast

Procedure: Excision with wire-guided localization

Lymph node sampling: Sentinel lymph node(s)

Specimen Integrity: Multiple designated specimens

Specimen Laterality: Left

Specimen Size: Greatest dimension 5.8 cm, Additional dimensions 4.5 x 2.0

cm

Tumor site: Not specified

Tumor size: Greatest dimension 1.5 cm

Macroscopic and Microscopic Extent of Tumor:

Tumor focality: Single focus of invasive carcinoma

Skin: Skin is not present

Nipple: Nipple is not present

Skeletal muscle: No skeletal muscle present

Histologic Type: Invasive ductal carcinoma

Histologic grade: Nottingham Histologic Score:

Tubule Formation: Minimal less than 10 % (score = 3)

Nuclear pleomorphism: Marked variation in size, nucleoli, chromatin

clumping (score = 3)

Mitotic count: Greater than 10 mitoses per 10 HPF (score = 3)

Total Nottingham Score: Grade III 8 - 9 points

Lymphatic Vessel invasion: Absent

Ductal Carcinoma In Situ: Absent

Extensive Intraductal Component (EIC): Absent

Lobular Carcinoma in Situ: Absent

Microcalcifications: Present in non-neoplastic tissue

Margins:

Invasive Carcinoma: Negative

Specify: All final margins >2 mm (see comment)

Ductal Carcinoma In situ: Not Applicable

Extent of Invasion:

TNM descriptors: None

Primary Tumor (pT): pT1c: Tumor more than 1.0 cm but not more than 2.0 cm

in greatest dimension

Lymph nodes: Number Examined: 2

Number with macrometastases (>0.2 cm): 0

Number with micrometastases (>0.2 mm) to 0.2 cm and/or >200 cells): 0

Number with isolated tumor cells (<= 0.2 mm and <= 200 cells): 0

Regional Lymph Nodes (pN): pN0: No regional lymph node metastasis

histologically

Distant metastasis (pM): pM: Unknown

Estrogen Receptor: See prior report: negative

Progesterone Receptor: See prior report: negative

HER2: See prior report: equivocal by IHC, negative by DISH

Biopsy site change: Yes

Additional pathologic findings: Usual ductal hyperplasia, apocrine metaplasia,

cysts

Comments: The invasive carcinoma is less than 1 mm from the inked

posterior margin in the main lumpectomy specimen (part A). The separately

submitted final posterior margin is entirely negative.

UHCMC Breast: Invasive Additional Testing: Tumor Block: A8

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  • Georgia1
    Georgia1 Member Posts: 1,321
    edited November 2017

    Good morning. I feel like the mods are going to be mad at me for giving medical advice, but my own pathology report was similar so here goes. That is a very good report. Smallish tumor, clean margins, no lymph node involvement. So yay for you! You may want to research the Nottingham score a bit more since you have three 3s on a scale of 1 to 3. It also looks like you are "triple negative," so your doctor will want to talk to you about treatments designed to minimize the risk of recurrence. But no DCIS, no LCIS, etc. is also good news.

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  • Motherofall6
    Motherofall6 Member Posts: 65
    edited November 2017

    thank you 😊 it’s opinions like yours I’m looking for so no one should get mad lol

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  • Motherofall6
    Motherofall6 Member Posts: 65
    edited November 2017

    what does no dcis and lcis mean lol I know I’m triple neg, stage 1a grade

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  • Georgia1
    Georgia1 Member Posts: 1,321
    edited November 2017

    Your tumor was invasive and ductal, which means it started in a milk duct and then "invaded" the surrounding tissue even tho it was relatively small. DCIS stands for "ductal carcinoma in situ," which would mean that you also had similar spots of cancer in nearby ducts that had not become invasive yet. So it's good the report says it is absent. LCIS is "lobular carcinoma in situ," which oddly is not really cancer but would mean that there is a change in breast tissue in one or more lobules that indicates you're at risk for further breast cancer. So that being absent is good news also.

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  • Motherofall6
    Motherofall6 Member Posts: 65
    edited November 2017

    oh ok thank you

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  • bhuffy038
    bhuffy038 Member Posts: 2
    edited November 2017

    EXAMS: Reason:: 

    Looking to understand this as they posted it online but have not called me although it could be they have and no service but, I do not have a voicemail either
    Any help appreciated. I am also awaiting the BRCA gene testing .

    003652175 US BREAST BX INITIAL RT RIGHT BREAST MASS 
    003652176 MAMMO DIAG DDI UNI RT POST BIOPSY 

     Addendum - 11/22/2017 SIGNED 11/22/2017 

     ADDENDUM: 003652175 US/USBRSBXIRT 003652176 MAMMO/MAMDDDIUR 
     Addendum: 

     Pathology showed fibrocystic changes with cyst formation and apocrine 
     metaplasia. No evidence of malignancy or atypical epithelia 
     hyperplasia. 
     Findings are congruent with imaging. 
     Six-month follow-up RIGHT ultrasound is recommended. 

     Findings telephoned to Dr.Cooper's nurse on 11/22/17 at 13:15. 

     Result Code: (4) SUSPICIOUS FINDING 
     Follow Up: (BX) RECOMMEND BIOPSY 




     ** Electronically Signed by Beata Panzegrau MD ** 
     ** on 11/22/2017 at 1347 ** 
     Reported and signed by: Beata Panzegrau, MD 
     Dictated Date/Time: 11/22/2017 (1314) 


     Report 

     RIGHT BREAST ULTRASOUND CORE BIOPSY 11/21/2017 

     PRE-PROCEDURE HISTORY/DIAGNOSIS: 
     RIGHT Breast lesion 5:00 

     POST OP DIAGNOSIS: 
     Same. 

     INFORMED CONSENT: Obtained 

     Patient properly identified. Appropriate imaging and records reviewed. 
     I discussed the procedure with the patient, and all questions 
     answered. Specifically, risks of bleeding, infection, allergic 
     reaction were discussed. Placement of a post biopsy marker clip was 
     also discussed. Consent form signed. 


    PAGE 1 Signed Report (CONTINUED)


     BREAST SERVICES Name: HUFF,BRANDY RENAE 
     CENTENNIAL MEDICAL CENTER Phys: Cooper,Mark E MD 
     2300 PATTERSON STREET DOB: 12/21/1978 Age: 38 Sex: F
     NASHVILLE, TN 37203 Acct: M00166069421 Loc: M.BREAST 
     PHONE #: 615-342-5018 Exam Date: 11/21/2017 Status: DEP CLI 
     FAX #: 615-342-5004 Radiology No: 
     Unit No: M002082129

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  • Georgia1
    Georgia1 Member Posts: 1,321
    edited November 2017

    Hi BHuffy. So that is a biopsy report, correct? We need an expert to weigh in but "no evidence of malignancy" sounds pretty good to me.

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