What was your treatment plan for TNBC

Hope you don't mind this post, and would like to say sorry you find yourself facing this again. I was Triple Positive and received 6 TCH for treatment. However, a very good friend was diagnosed a couple of years after I was with BRCA1+, node neg, grade 3, stage 2 (3cm tumor) Triple Negative breast cancer. She was 35 at the time, had no family locally, so I accompanied her to her consults, surgeries, and chemo treatments. She was treated at the same practice I was, but by a different oncologist who specializes in younger patients. She had neoadjuvent chemo after a SNB and port install surgery - so, her nodal status was confirmed. She completed 3 dose dense AC, then developed an infection at the port site, so discontinued and had bi-lateral mastectomy with recon, then resumed chemo with weekly Taxol after surgery. She has since had an oophorectomy due to her BRCA1+ status, and is doing well. There is a lifetime limit on Adriamycin, to reduce the risk of cardio-toxicity and MDS, and I believe it is up to 550mg. Are you being treated by the same oncologist? Knowing your total dosage of A to date would be important. I have seen some receive TC for TN, and there has been a resurgence of the use of CMF, an older but gentler regimen, specifically for TN patients. It would be valuable to look at the threads here for Triple Negative - go to the All Topics bar on the left and look for that category and you will see several threads, these folks may be able to provide additional advice and insight. Wishing you the best.

Hey,

I had 4 rounds of AC and I just had my first of 12 Taxol today. Then a lumpectomy. Then 4 to 5 weeks of radiation. I am stage 2B and my tumor is 2.8 cm

Dear mjkurtz - I am so very sorry you are going through this a second time.

My treatment plan? I am having chemo before surgery: 4 sessions of dose dense AC followed by 4 sessions of Taxol/Carboplatin. (I just had my first AC session this afternoon.) I am waiting to get my genetic testing results next week. As of now I am planning on a uni- mastectomy. If I have a really high risk I may go bi. After surgery I'll have radiation, but we haven't discussed the details of that yet.

Good luck with everything!

I did 4 rounds of AC and 12 rounds of Taxol. I was Stage 2A, triple negative, Grade 3, 1.7 cm tumor, 1 lymph node positive.

surviving today....I'm wondering why myself. He said this in the very beginning but all the reading I'm doing, im wondering if this will still be the case. I will definitely question him on this matter!

I had an > 8 cm triple negative tumour with negative nodes. Due to the tumour size I had neoadjuvant chemotherapy. 4 cycles of 5-fluorouracil, epirubicin, & cyclophosphamide followed by 4 cycles of docetaxel [I was FEC'D ]. That was followed by a radical mastectomy and then 5 weeks of radiation therapy (dose of 5000cGy in 25 fractions).
Two years later (this past April) I had a DIEP Tram flap breast reconstruction.
I am over 2 and a half years cancer free right now, and grateful for every day. The size of my tumour scared me, but all seems to be good now. I'm sorry you have to go through all this again, but I hope it helps a little to know that there are new drugs and radiation techniques now that make going through all this easier.

I had bilateral mastectomies and one dose of chemo. I was cut off chemo after the first infusion because I developed diverticulitis even though I am grade 3. I have been fine for over 4years in spite of being obese and in bad shape in general. It really is a crap shoot. So sorry you are having to deal with it again. It isn't fair.

Hi, I'm a bit behind on these posts. I was diagnosed with TNBC November 8, 2017. I have the BRCA1 mutation.

So far I have had a bilateral mastectomy with immediate reconstruction and have just completed my 4 rounds of dense dose AC and start 4 rounds of Taxol in 2 weeks followed by 25 rounds of radiation.

After radiation I am scheduled to have my tubes and ovaries removed.

I am sorry that you are having to go through this a second time. I have been told from my oncologist that if TNBC is going to re-occur that it would happen within 5 years but obviously this is not the case.

Can I ask, since you had abilateral mastectomy with reconstruction, where did the re-occurrence happen

April-May, welcome to our community, and thank you for sharing all you are going through. Since the last post before yours was from Oct 22, 2017, you may want to send the person you are questioning a private message. Click on their name, and then you can message.

Char105, yes, genetic testing can sometimes help guide your treatment plan. You may find our section on Genetic Testing helpful, as well as our 3-part podcast series Genetics, Genetic Testing, and Breast Cancer: Part 1.

Did your doctor help you understand why they would like to do the genetic tests, given there is no family history?

Hello,

I start a FEC-D regime on Monday. Three week doses with three of FEC followed by three of D. I read somewhere that this regime is not common in USA and more popular in UK Canada and AUS. I wonder why?

So I am with RTchris and hope my TNBC gets totally FECD!

All being well I will follow up with surgery and radiation to the lymph above my breast bones.

Today I am having MRI for brain and GHPT for heart. Onc says TNBC likes to go to brain and the E in FEC can impact your heart. Feel like I'm in dream and not a very pleasant one.

The boards have been good to read for information but also to see the support and community created.

Thanks for reading and good luck to you and your families.

triple negative stage 1 grade 3 no node involvement and had genetic testing done all came back negative

I had lumpectomy nov 10, Jan 3 I started chemo with 4dose AC , I’m done with 7/12 weekly taxol and will start radiation 33 sessions starting June