Oncotyping scores

susie_2017
susie_2017 Member Posts: 155
edited July 2017 in Stage I Breast Cancer

I tend to read people's posts and then their signature lines with their status of stage, grade and whether or not they needed chemo. What I'm also curious about is the Oncotyping scores. Perhaps it's because I haven't seen one higher than mine yet. So this thread is started to see if there is some as high as mine!

My score was 44.


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  • NancyHB
    NancyHB Member Posts: 1,512
    edited July 2017

    Hi Susie, I'm not higher but close: 42 first diagnosis. Second dx was TNBC so no need for Oncotype testing as I'd definitely need chemo

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  • susie_2017
    susie_2017 Member Posts: 155
    edited July 2017

    NancyHB sorry you had to deal with cancer twice. When I had my biopsy after mammogram they said I was ER+, PR+and HER2 -. Therefore my tumor was sent out for Oncotyping. However when it came back my BS said I was triple negative. I asked how this came to be and she said the biopsy results were very weak positives. Basically it's dropped in blue dye and read by a human, leaving room for human error. And since my actual tumor was removed and labelled as a triple negative that's what I will be considered. Now we are treating it very aggressively.

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  • NancyHB
    NancyHB Member Posts: 1,512
    edited July 2017

    Susie, mine was similar to yours. Initial path was ER+/PR+, but Oncotype testing came back weakly ER+ (less than 10%) and PR-. My MO said any ER+ is a good thing so we proceeded as though I was positive (then again, he also said he'd never seen a score as high as mine). My high score allowed me to participate in a clinical trial, which was very interesting and informative (dd Taxol x 6, which they ultimately declared to have more pain-related SEs and a lower rate of disease-free survival, so no advantage to it).

    Odd as it sounds, I was happier with a high score; my biggest fear was ending up in the dreaded intermediate area. Although I would have been equally happy with a 1. 😊

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  • Kaso
    Kaso Member Posts: 61
    edited July 2017

    My surgery was 5days ago- lumpectomy and sentinel node biopsy

    I was told there was not enough tissue for onctotype and that what was viewed in surgery implied to the surgeon that it was not necessar

    I was hoping for assurance that guides treatment with the onctotype.


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  • lrwells50
    lrwells50 Member Posts: 254
    edited July 2017

    Everybody told me I wouldn't need chemo, but my labs said ILC instead of IDC, and more likely to recur, and my OncotypeDx was 24, right in the middle of the intermediate range, so I'm doing chemo

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  • Legomaster225
    Legomaster225 Member Posts: 672
    edited July 2017

    I scored a 39.

    Pathology report said 23%ER 10%PR. ONCO testing classified it as negative. Drs are treating it as if it's positive similar to NancyHB.

    If I had known low score wins I would not have studied so hard for this test

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  • carmstr835
    carmstr835 Member Posts: 388
    edited July 2017

    Hi Susie, My left breast was oncotype 17 and my right was oncotype 19. My oncologist did not recommend chemo, but my 2nd opinion oncologist did. I also had the pathology redone and it confirmed the original biopsy Her2+ diagnosis. So 1/2 way through my chemo, it was changed from TC to TCHP.

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  • LimnoGal
    LimnoGal Member Posts: 157
    edited July 2017

    Susie-apparently I studied much too hard for my oncotype, because I scored a 49. I was like you and many others with high scores, weakly ER+(36%), PR - and HER - . Off to chemo I went.

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  • susie_2017
    susie_2017 Member Posts: 155
    edited July 2017

    Finally! Not that I'm happy you scored as high as me but I'm happy I'm not alone! I wonder how many have higher scores from years past and did the cancer return? I hope not! Right now I'm going through chemo and hoping/praying it's the last time I ever have to do It!

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  • Meow13
    Meow13 Member Posts: 4,859
    edited July 2017

    My oncodx was 34, it was like a knife through my heart. I said no to chemo so 23 % risk of recurrence with tamoxifen but who knows what risk with anastrozole. I did AI drugs for 4 years. They really down play the side effects and I am finding some are permanent. Still NED at 6 years.

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  • susie_2017
    susie_2017 Member Posts: 155
    edited July 2017

    Meow Congrats on the 6 years! That's encouraging!

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  • sybilskelton
    sybilskelton Member Posts: 77
    edited July 2017

    My oncotype score was 68, doctor said it was the highest she'd ever seen. The cancer was stage IIa with clear margins and no lymph node involvement, but I still did the chemo and radiation. That was three years ago, but sadly it's come back - bone mets. I guess they were right about the aggressiveness.

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  • ChiSandy
    ChiSandy Member Posts: 12,133
    edited July 2017

    sybil, I’m confused—your profile and post say Stage IIA, but your post says DCIS, which is Stage 0. Which was it?

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  • sybilskelton
    sybilskelton Member Posts: 77
    edited July 2017

    LOL, I must have screwed that up when I was clicking on boxes. I honestly never went back and checked it but I will now. It was originally IIa.

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  • Meow13
    Meow13 Member Posts: 4,859
    edited July 2017

    Sybil, so sorry it came back and you did the chemo! Ugh, are you having radiation for bone mets?

    One of my coworkers had 1cm ILC close to her chest wall her oncodx was 4. I was so jealous but 6 months later she had mets to bone. She thinks it was probably there when she was first diagnosed.

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  • Hopfull2
    Hopfull2 Member Posts: 418
    edited July 2017

    hi Susie, my score was a bit lower than yours a 39. All my docs thought for sure no chemo. I was already meeting with my plastic surgeon to start reconstruction then I got the phone call by my MO and he said sorry to tell u but your score was hi 39. I cried. I thought I would never get through chemo especially with 2young children. But I did. You will too. Sorry about your score

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  • QuinnCat
    QuinnCat Member Posts: 3,456
    edited July 2017

    I see a lot of 39's here! I was Stage IA, dx'd 11/11/11, 1.4 cm, grade 3. IHC ER was 90%, PR 5%. My Ki67 was 60%. Got clear margins, no node involvement. Oncoscore came back as 39. Sorry, no numbers in front of me, but ER came back as still positive, but more middling than what 90% IHC looked like. PR was just barely in the positive range on the genomics report. Had DD AC/T than 5 of 6 Carboplatin treatments because the head MO at OHS felt carboplatin worked well on BRCA cancers. I am brca2+. My feet were thrashed by Taxol and the platin was the icing on the cake, but I'm still NED 5 years later.

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  • QuinnCat
    QuinnCat Member Posts: 3,456
    edited July 2017

    Susie, being TN makes the oncoscore less useful, though I know TN and Her2+ breast cancers would always score much higher than er+ cancers, in general, if happenned to be tested by genomics. It seems like 44 for a TN might be viewed as low, then, for the TN domain, by the mere fact that er and pr receptors are absent, or in the case of her2+, those receptors are present. Also, I've seen higher scores than 44 for a handful of er+ individuals

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