Hormone Replacement Therapy & TNBC

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chi-girl
chi-girl Member Posts: 21
edited June 2017 in Triple-Negative Breast Cancer

I've been having memory issues for the past 5 years. (ChemoFog that never went away.) My working memory is awful, I can't focus and I can't multitask. It's very frustrating.

I'm seeing a neuropsychiatrist and I just did neuropsych testing. The neuropsych testing came back fine. But I'm not fine. I wish I had done a baseline prior, but I didn't realize memory issues was a potential side effect of treatment.

I went into Menopause with Chemo. My OB/GYN thought that Estrogen/Progesteren might help and she thought that it should be okay because I'm TN. I asked my Oncologist what he thought. He said it would probably be okay, but that I should exhaust all other avenues first. Hence the neuropsychiatrist.

We've ruled out sleep (I'm now on CPAP), Depression--I just told them to give me an anti-depressive pill so I could prove it wasn't that, and the neuropsych testing. Nothing's working and I'm at my wit's end.

Long story short, has anyone here taken HRT with TNBC? Or is that not a good idea? And if you have taken it, does it help with your memory?


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  • maryna8
    maryna8 Member Posts: 1,810
    edited June 2017

    HI, ChiGirl,

    I was on HRT for almost 20 years, and was on hormone vaginal suppository, very light dose, when diagnosed with BC in 2014. I am now 64. My MO told me to get off the HRT, so I have been off since 2014. He said that TNBC can start out as E+P+ BC and then mutate to TNBC, so no added hormones as far as he's concerned. I don't know if HRT would help your memory or not, it sounds like it would be a trial and error thing with possible unwanted results from the HRT, if you believe my doc's opinion. I hope you have some success with something you are trying; how long have you been on the anti-depressant? Sometimes it takes a while for that to kick in. Good luck, my thinking is pretty scattered these days too, I find I do much better if focused on a task instead of trying to tackle many things at once.

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