Possible new treatment/study drug for TNBC

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LovesLoons
LovesLoons Member Posts: 68
edited May 2017 in Triple-Negative Breast Cancer

Note: This will take you to a PDF. It doesn't seem to download automatically though ... it just takes you to a website/PDF. Anyway --- Click Here If you don't want to do that, Google something like : Talazoparib: A Potentially Best-In-Class PARP Inhibitor to find more info.

I am on this med with Irinotecan for the I-Spy 2 trial. I know we don't really have many options for treatments, so I thought I would let anyone know about this info.

There is more than breast cancer on this link, but I couldn't really separate it out. Pg 30 has the BC info, especially for those BRCA positive. Some don't like all the technical stuff about how it works, but I love that.

I don't know if I am BRCA positive or not, but they are trying it out in TNBC patients, MammaPrint High risk, a few other qualifications. You can check out the Ispy-2 website for more info; I think there are other trials, like the EMBRACA trial listed on one of these boards; maybe one closer in your area. It looks pretty promising I think.



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  • cmix01
    cmix01 Member Posts: 3
    edited May 2017

    My mom is a triple negative patient with her 3rd recurrence in five years and we are looking at options. What has been your experience with this? She does not have the BRCA gene.

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  • mike3121
    mike3121 Member Posts: 410
    edited May 2017

    My wife is now triple negative as her ER+ turned. This new drug sounds real interesting. It says it's really powerful and has a high rate of effectiveness, however, I couldn't find how many subjects it helps. Maybe highly effective with 10% of subjects?

    PDF worked great for me. Thanks.

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