Anastrazole & muscular tinnitus

Thanks - but that's a different issue than I'm asking about (which is why I started a new thread, rather than diving into the regular tinnitus threads).

I've had regular old tinnitus for as long as I can remember. It's a bit worse. Before anastrazole it was limited to my right ear - now it is in my left as well part of the time - but it is connectd to hearing loss in the frequency range of the tinnitus so since the left ear has now caught up to the right ear as to hearing loss, it may beunconnected to the anastrazole.

This is completely different - it is much more sensation than sound (although there is a bit of sound with it). If you ever get a muscle twitch - that's what this is like insice the ear, but pretty rapid, all day long, about every 11-12 minutes.

Apparently it is a rare form of tinnitus - and side from sharing the same label (tinnitus) - it doesn't have much in common with the ringing-in-the-ears tinnitus.

I've searched (discussion board, google, pub med, side effects database), and I haven't found anyone else who has it in connection with anastrozole. The CNP who evaluated me at the ENT doc did not seem surprised at all, though, and it makes perfect sence since (generally) anastrazole is doing a number on my nerves/muscles. So I'm surprised I haven't run across fellow sufferers.

I went in with a self-diagnosis - and I have enough of a history of being pretty accurate that they take me seriously when I walk in and describe what's going on - with or without a suggestion of what I think it is. They were concerned about potential hearing loss (because anastrazole is an ototoxin) - but no signs yet.

The ENT put me no magnesium and, if it isn't gone in 3 weeks, they want to add calcium channel blockers. Both address muscle spasms.

I've been experimenting with position, to see if it makes a difference in triggering it or relieving it. So far, no luck. Tensing up (to move, for example) and spontaneous yawns seem to trigger it. But it also starts randomly (since it's happening every 11-12 minutes, that's not too surprising).

Is yours still going on?

I haven't had muscle cramps before - they are new. But I've had restless leg for years - it had a characteristic time (ending ~2 AM), and was mostly gone the last few years. It started instantaneously when I started anastrazole - at a different (more intolerable) time (starting ~5:30 AM)

katcar0001 I got to muscular tinnitus by looking up ear fluttering - not really expecting to find anything, but what popped up was muscular tinnitus. The ENT didn't pin down whether it was the tensor tympani muscle or the stapedius muscle that is spasming (they tried to catch it - but the device they used changed the pressure in the ear canal and calmed it down during the test). I've seen both of the options you've named connected to what I'm experiencing

We'll see how I get along with the magnesium. It isn't annoying enough (yet) to want to try valium - and if it gets that annoying, I'll try a different AI before I try valium. I need my brain to be sharp.

Bagsharon - I don't think I'd describe it as tickling, but there are two muscles that can be involved. Different muscles might feel different.

I'm just excited to know I'm not the only one experiencing this - since couldn't find any reports in the side effects databases.