Femara/lupron and Irritability

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4girlsmom
4girlsmom Member Posts: 27
edited March 2017 in Hormonal Therapy - Before, During, and After

I started Femara (and Lupron shots) less than a month ago and am feeling fussy and irritable from practically the moment I wake up. I am normally a positive happy person, and I feel like another personality has taken over me. Has anyone experienced similar symptoms and had them simply go away with time? I don't want to start an additional medication (or switch AI's) if this is something I should just ride out. I also wonder if anyone has found relief through some other change (taking a supplement, yoga, etc?). Thank you for sharing your experience!

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  • Moderators
    Moderators Member Posts: 25,912
    edited February 2017

    bump for 4girlsmom -- can anyone weigh in with their experiences?

    Thanks!

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  • dsteaparty
    dsteaparty Member Posts: 28
    edited March 2017

    I just started Lupron shots last week and I'm taking tamoxifen. After I go into menopause in a few monthsI should switch to femara. I just wanted to say hi and that I'm watching this thread to see what anyone has to say. My doctor told me that tamoxifen made people depressed and I asked if I could start an antidepressant now so I didn't have to get depressed. She gave me citalopram And I started all three new meds together. Last week I was really tired and fuzzy head but this week seems better. I have just been diagnosed and it all seems very surreal. It also seems strange to just take a pill and get a shot for 6 months instead of surgery first. But truthfully I am petrified of surgery and I am happy to put that off.

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  • laguapagirl123
    laguapagirl123 Member Posts: 1
    edited March 2017

    I just started Lupron injections and leprozole this week. I had a primary diagnosis in 2012 and then a recurrence in 2014 followed by chemo and radiation. I have been taking Tamoxifen as I am pre-menopausal and I recently started having issues caused by the Tamoxifen. My Oncologist decided to have me stop that and switch to these two drugs. I am also feeling pretty irritable. I have heard it can cause this...I hope it goes away too. If not my next step is probably to have a hysterectomy and try tamoxifen again. I hate all of the constant decisions I feel like I am faced with especially since none of them seem like a "best" choice kind of thing. The Doctors don't know who will react and what reactions they will have so it's like stabbing in the dark hoping to hit the mark. Let me know if your symptoms get any better and I will try to follow up as well. It's always a comfort to know there are others out there going through similar experiences. I will be hoping the best for you!


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  • Falconer
    Falconer Member Posts: 1,192
    edited March 2017
    Hi dstea and lagua,
    Sorry to see you here in Lupron land, but glad you found this community as you can get lots of great help here on the BCO.
    I've been on Lupron since November and my moods are swinging like Tarzan. Acupuncture has helped as I'm not much of a medication person. I also upped my Vitamin D and try to exercise as much as possible. Your experiences are like many other women here on this site so if you search the hormone therapy thread you'll see you're not alone. You'll get through this.
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