PIK3CA Genetic Mutation

Options
Rseman
Rseman Member Posts: 281
edited February 2017 in Stage IV/Metastatic Breast Cancer ONLY

Hello All-

I am curious if anyone else knows that they have the PIK3CA gene mutation and what treatments or clinical trial you are on as a result.

We have determined that the hormonals have stopped working for me and Eribulin just failed. Xeloda also failed for me. I am now searching for other treatments.

Thank you for any input you may have!

Rene

· Share on FacebookShare on Twitter

Comments

  • Cure-ious
    Cure-ious Member Posts: 2,626
    edited February 2017

    Hi Rseman,

    Do you know if you have the PIK3CA mutation? Please give a more detailed accounting of the order and length of time of your treatments? We love searching trials and treatments- have you had genetic testing? Am bumping this thread back up so more can respond

    · Share on FacebookShare on Twitter
  • Rseman
    Rseman Member Posts: 281
    edited February 2017

    Hello-

    I do have the PI3KCA mutation. I had genetic testing done that discovered it. I have been on hormonal and chemotherapy treatments (a total of 6 different protocols). I have them detailed in my profile.

    Thank you so much for your assistance, And please excuse the misspellings above

    Renee

    · Share on FacebookShare on Twitter
  • keetmom
    keetmom Member Posts: 432
    edited February 2017

    Have you looked at the NCI Match trial? NCT02465060 on clinicaltrials.gov

    · Share on FacebookShare on Twitter
  • Rseman
    Rseman Member Posts: 281
    edited February 2017

    Unfortunately I was rejected by the Match trial because I have a pacemaker. However, my oncologist thought it important to go through the same denetic testing and that is how we determined I have a mutation. So now I am trying to find the best treatment fit.

    I'm actually getting nervous as I'm not on any treatment right now and probably won't be for over a month as we look for something

    · Share on FacebookShare on Twitter

Categories