Basal vs. Non-Basal TNBC?

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VLH
VLH Member Posts: 1,258
edited January 2017 in Triple-Negative Breast Cancer

In educating myself about triple negative breast cancer, I've learned that while most TNBC is basal-like, that's not always the case. In reviewing my biopsy and post surgical pathology reports, I can't find that cytokeratins were analyzed and that is apparently important in identifying whether the tumor was basal along with the EGFR status. I had the Foundation One molecular test run and don't have the EGFR mutation.

Did your pathology reports include cytokeratin information? I recognize that I'll either recur or not, but I'm a naturally curious person so it's my nature to want to analyze available research relevant to my diagnosis and prognosis.

Thanks, Lyn

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  • marias245071
    marias245071 Member Posts: 270
    edited January 2017

    Hello Lyn !!. Im triple negative too and the doctor send me the test of ck-5/6, CK-14 and EGRF. They all give positive. So the doctor say Im fenotipe Basal-Like too.

    They do to u the same test. Now the doctor send me the genetics one. BRCA1 y BRCA2.

    I hope this words give u some information u need.

    My best wishes to u

    Marias


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  • VLH
    VLH Member Posts: 1,258
    edited January 2017

    Thank you, Marias. Unfortunately, I'm annoyed that neither of my pathology reports included the CK information. As I mentioned, I know I don't have the EGFR mutation. Neither am I BRCA positive. Best of luck to you.

    Lyn

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  • RuthElizabeth
    RuthElizabeth Member Posts: 103
    edited January 2017

    hi, my name is Ruth. I had tnbc back in 2015. Bilateral mastectomy and chemo. No nodes involved. I tested negative for the BRACA 1 and 2. Only reading up now, on the Basel. I have a check up in March. My doctor at this point only wants to do a blood test. I am terrified of reoccurrence. Just curious who out there is having better testing, and what should I ask fo

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