High white blood cell ratio linked to recurrence

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  • MTwoman
    MTwoman Member Posts: 2,704
    edited January 2017

    BarredOwl, I read the full article "Prognostic role of neutrophil-to-lymphocyte ratio . ." and in the methods section, they define it as, "NLR collected prior to all treatment (surgery and/or systematic therapy)"


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  • MTwoman
    MTwoman Member Posts: 2,704
    edited January 2017

    ErenTo,

    there is discussion in the results section of the study about "statistically significant heterogeneity" for OS, which seemed to resolve when subgroup analysis was performed including only early-stage disease. However, for DFS, there was no evidence of statistically significant heterogeneity and included women who had both early stage and metastatic disease status. The effect of NLR appears to remain in the participants regardless of the stage of their disease.

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  • BarredOwl
    BarredOwl Member Posts: 2,433
    edited January 2017

    Thanks for checking that MTwoman. I would still take it to mean that measurements not taken "pre-treatment" within the meaning of the study (e.g., four years later) are not what has been assessed, such that the same correlations may or may not be observed.

    BarredOwl

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  • MTwoman
    MTwoman Member Posts: 2,704
    edited January 2017

    me too


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