Prophylactic Ovary Removal to induce menopause?

Options
gailpet
gailpet Member Posts: 20

Finished radiation on 10/31/16 -- met with MO last week to discuss anti-hormone treatment. I am 50 but no where near menopause according to blood tests (might be years before I'm there!). Due to high risk of blood clots for me and due to family history, my MO recommends that I don't take Tamoxifen and instead, have my ovaries removed to induce menopause so I can take an aromatase inhibitor instead (probably Arimidex).


Just curious if anyone has had this surgery done and what to expect as far as "instant" menopause? Surgery should be done laparoscopic so hoping for not too much down time so I can get back to work within a week or two at the most.

Thanks!

Comments

  • farmerlucy
    farmerlucy Member Posts: 3,985
    edited December 2016

    I did it last year. Even at 55 it was hard to lose that estrogen. The surgery itself was easy, and I was back to normal activity the next day, though I was a bit fatigued. The worse part of surgery was the CO2 rising to my shoulders looking for a place to escape. They have to "inflate" the area to see things. Ironically I did the ooph to move on to an AI, but after ten months I switched back to Tamoxifen. For me the joint issues were too much. It is a relief to take the ovarian cancer issues off the table.





  • CareyShay
    CareyShay Member Posts: 6
    edited December 2016

    I'm glad this question has been asked, and I hope more people reply.

    I will be undergoing this surgery after radiation and I am only thirty. There is a strong history in my family and my mother currently has stage four after being cancer free for fifteen years.

    The surgery was my idea, but has been strongly encouraged by my oncologist since my recurrence rate is high due to my age and being BRCA2 positive.


  • lintrollerderby
    lintrollerderby Member Posts: 483
    edited December 2016

    CareyShay, welcome and we're sorry you have to be here. It's good that you know your risk is high. My daughter plans to have a BSO by age 30. She had a PBMX with recon at 20. It sucks, but good to know that your risk is so elevated.

  • Moderators
    Moderators Member Posts: 25,912
    edited December 2016

    Hi gailpet and CareyShay,

    You may want to check out the main Breastcancer.org site's pages on Prophylactic Ovary Removal for some great information on risks, what to expect, and questions to ask your surgeon.

    We hope this helps!

    --The Mods

  • CareyShay
    CareyShay Member Posts: 6
    edited December 2016

    Thank you for the link and info! I have read a lot about it, but was looking for some information from people who have experienced it. With the lack of activity I guess many people on the forums have not opted for the surgery.

  • lintrollerderby
    lintrollerderby Member Posts: 483
    edited December 2016

    CareyShay: being BRCA2+, have you checkout out FORCE--facingourrisk.org--as it's a great resource for us who have BRCA mutations. It's usually advised for us to have the PBSO rather than just the ovaries because there's concern in BRCA mutation carriers that oftentimes the "ovarian" cancer is actually from the fallopian tube instead.

  • gailpet
    gailpet Member Posts: 20
    edited December 2016

    Thanks for the link for the information -- I did read the information but also was looking for some people who have gone through it personally!

    CareyShay -- I don't have the BRCA mutations and I also had a few other genes tested. I know my oncologist and Gyno suggested both ovary and Fallopian tube removal for the same reason that lintrollerd suggested. Since I didn't test positive for the mutations, I don't know that I am at an elevated risk for ovarian cancer but need to get them removed to enable me to use a different anti-hormone drug other than Tamoxifin which is for pre-menopausal use.

    Good luck!

  • Logang
    Logang Member Posts: 421
    edited December 2016

    I get monthly zoladex injections to supress my ovaries and take aromasin. I have contemplated the ovary removal, but never really decided. I have had my other surgeries instead. Still may go this route sometime next year.

  • Michelle_in_cornland
    Michelle_in_cornland Member Posts: 1,689
    edited December 2016

    Okay, I have got this question, Ladies. I have been working with my doctors, MO and Gyn to generate options because I can't take Tamoxifen with an SSRI (Zoloft). With all of my research, and I have been at it for 3 months, I am going to try the Lupron shot to shut down my ovaries. After five years of meds or whenever my hormones signal that I am post menopause, I will stop the shots. At the end of my five years, I will still have ovarian function which supports bone health and heart health in women. I think an annual CA125 is appropriate to make sure you are not at risk for ovarian cancer. I did mine in Nov to see if there was a substantial reason to have my ovaries out. My test came back extremely low and my MO said keep your ovaries and see how you do. We will do hormone checks every few months to monitor my levels. I am early 50s and no where near menopause. My MO thought radiation would kick my body into menopause, instead, I have normal monthly cycles. I have started a discussion under on the Hormonal board - "Uplifting........." You should join us, we are mostly in the same boat.

  • Lucy55
    Lucy55 Member Posts: 3,044
    edited December 2016

    Gailpet ..I had my ovaries removed 2 months ago ..along with a hysterectomy...The actual surgery was very easy ...but I had gone through menopause 2 years ago , so It wasn't surgical menopause for me .

  • CareyShay
    CareyShay Member Posts: 6
    edited December 2016

    Thanks for the additional input everyone! I was aware it would be both fallopian tube removal along with ovary removal, I must have just forgotten to type that part in :)

    lintrollerderby- Thank you for the additional website recommendation, I'll head over there shortly to check things out.

    My main interest was in pushing early menopause so I can take something stronger than tamoxifen. My mothers breast cancer came back within fifteen years of her initial diagnosis, and I have been diagnosed fifteen years earlier than she initially was. It indicates I have a more aggressive cancer - in theory.

    I was also told I will likely be on hormone suppressors for ten years instead of the more common five. This means that even when my ovaries are "woken back up" from the shots, I will be forty, with much lower quality eggs. I went through two rounds of IVF prior to chemo, with a total of 31 eggs frozen. So babies can still be on the table for me.

    I appreciate everyone's feedback. It is helpful hearing so many different perspectives. Thank you all for taking the time to share and reply!

  • SpecialK
    SpecialK Member Posts: 16,486
    edited December 2016

    I had a TAH/BSO when I was 45 and definitely pre-menopausal, 9 years prior to diagnosis with breast cancer. I had both a uterus full of fibroid tumors, pathology stated "too numerous to count", and a surprise 3cm pre-malignant ovarian mass. I did experience pretty intense hot flashes - still do 15 years later, I had pretty sudden elevated cholesterol when it had previously been excellent, and bone density loss, although I am a physical candidate for that - it might have happened anyway. Other than these issues, surgical menopause was not too difficult. I would recommend having a cholesterol test, and a DEXA scan done as a baseline prior to surgery. I do have a good friend who is BRCA 1+, had successfully treated TN breast cancer at 35, and elected a BSO but left the uterus. She had an easy recovery, and so far has had some hot flashes, but not bad. Because she is TN she is not on any anti-hormonals

  • LRGinger
    LRGinger Member Posts: 30
    edited December 2016

    I did the Zoladex shots for one year and then opted to have my ovaries and tubes out. The surgery was failrly easy, though I ended up with a surgical complication that required an emergency surgery ( just one of those random things). I already had hot flashes and the only new problem after the surgery was night sweats. I was tired of doing the shots and nowhere near menopause, but I wanted to be on an AI because of the data showing better results. I'm glad I had it done Good luck making the decision!

  • gailpet
    gailpet Member Posts: 20
    edited December 2016

    My surgery is set for next week -- nervous but glad the ovaries and tubes are gone -- just a couple more areas that I won't have to worry about cancer popping up! :)

Categories