Johns Hopkins develops free app to estimate recurrence.

Interesting because it uses Ki67 to add a proliferation factor on top of grade, which also factors that in.

One thing to keep in mind is that Ki67 can very widely depending on what lab is testing it and when the tumor is tested. Ki67 results can increase when tested on surgical tumors after a needle biopsy. Cell proliferation increases reflecting the effort to repair the damage of the biopsy, making it appear that a tumor is more aggressive than in the biopsy.

This aligned with my Oncotype score. These tools often don't work for my tumor. I am a high grade two and averaging grade two results with grade three drew a match. My tumor was removed in full with a surgical biopsy, so I feel relatively confident that the Ki67 is relatively accurate.

Edited to add: For those of you HER2+++ I played around and plugged in positive. I'm always curious because my tumor tested at +1, not high enough for additional testing. For grade two, the risk moved up a point and for grade three, it declined. Very interesting. I think it shows how effective treatment is now for HER2 +++ breast cancer.

Was the Ki67 % from your biopsy or surgery? Also, tumors are not homogenous throughout.

Also I think oncotype is still necessary. The Ki score is only one part of the picture and most top centers don't even use it

I just pulled out my pathology report to see if I could utilize this link....all along I thought I was grade 2, but turns out I was grade 3. wth??

Anyway, my pathology doesn't give a clear KI-67, just says Intermediate approx 10% of cells staining.

It's probably for the best that I don't get into these things, it's like a big ole rabbit hole for me.