Hormonal Therapy and Anxiety

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Girl53
Girl53 Member Posts: 225
edited September 2016 in Hormonal Therapy - Before, During, and After

All: Have been on anastrozole for exactly five months. Joint pain and stiffness I had at first is now a lot better, thank goodness. But now am having real anxiety, too. Wondering if anyone has insight on whether emotionally susceptible women may get pronounced anxiety on any drug that lowers your estrogen as much as anastrozole does. AND, if so, can we expect it to ease up when the body adjusts? Any input/insight appreciated. Thanks so much.

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  • ChemicalWorld
    ChemicalWorld Member Posts: 172
    edited September 2016

    I am not on anastrozole but am on a tamoxifen / lupron combo. I have noticed a definite increase in anxiety since starting the lupron in particular.

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  • Anonymous
    Anonymous Member Posts: 1,376
    edited September 2016

    Arimidex (anastrole) caused huge mood swings for me, so having anxiety from it too is likely. Trigger thumb and finger, bloating, fatigue, depression. Lovely stuff ;)


    I had to stop it and switch to Aromasin (exemestane). I'm doing much better on it.

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  • KathyL624
    KathyL624 Member Posts: 217
    edited September 2016

    ChemicalWorld, I take tamoxifen and do Lupron shots as well and it does seem like my anxiety has worsened. Are you sticking with tamoxifen or switching to an AI at some point?

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