Ki-67?

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KathyL624
KathyL624 Member Posts: 217
edited August 2016 in Stage I Breast Cancer

I read a lot about Ki67 on these boards, but it is not in any of my pathology reports, nor have any doctors mentioned this to me--all I have is my grade (1) and oncotype (9) as any measure of proliferation. Do some hospitals not test the Ki67?

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  • MsPharoah
    MsPharoah Member Posts: 1,034
    edited June 2016

    Hi Kathy.....and congratulations on the low grade and oncotype DX result. You are correct that not all pathologists measure Ki67. Ask your surgeon or oncologist about this test. Since the oncotype DX test includes Ki67 as part of the proliferation genes and since you have a low oncotype result, I would suspect that you are very highly ER/PR positive and have a low Ki67 rate.....but I'm not a doctor.

    Good luck on your treatment and recovery.

    MsP

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  • KathyL624
    KathyL624 Member Posts: 217
    edited June 2016

    Yes, I was 99% ER and 95% PR. I started at a local hospital then ended up with treatment at Sloane Kettering, and neither place ever mentioned it. I will ask my oncologist at my next visit though.

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  • Anonymous
    Anonymous Member Posts: 1,376
    edited June 2016
    kayb that's what I've read too.
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  • Meow13
    Meow13 Member Posts: 4,859
    edited June 2016

    I had an oncodx test but I never got a ki67 result.

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  • ChiSandy
    ChiSandy Member Posts: 12,133
    edited June 2016

    Same here as Meow13.

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  • cp418
    cp418 Member Posts: 7,079
    edited June 2016

    Note too when reading any articles that it was older data back when they tested for Ki67. Oncotype and other testing appears to be replacing it.

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  • 614
    614 Member Posts: 851
    edited June 2016

    I had a Ki67 test but the oncotype test trumped my ki67 score.  I did not need to have chemo.

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  • Lisey
    Lisey Member Posts: 1,053
    edited July 2016

    my Ki67 was 30-35%. My oncotype was 20. The doctor was pretty confident about no chemo. I brought up the high ki, and she dismissed it, saying it could have been from my breast recovering from the biopsy. Is that true? Are there any studies that support that hypothesis?. My miteosis was a 1 in the biopsy. I'm in a second guessing myself mood.. as every paper I read says high ki, low pr+ value = luminal B. Argh I need my blueprint results... waiting til Friday is gonna suck.

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  • 614
    614 Member Posts: 851
    edited July 2016

    Good luck with your results.  The waiting sucks.  It is also horrible to be in the grey area on the oncotype test.  I wish you the best.  Go for a second opinion if you are unsure. 

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  • Lisey
    Lisey Member Posts: 1,053
    edited August 2016

    Just to follow up.. Mammoprint gave me a Low Risk score, and they tested me twice to confirm. I'm luminal A and my Onc thinks the ki-67 score was a patholigist error/eyeball exaggeration. No chemo for me.

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  • 614
    614 Member Posts: 851
    edited August 2016


    "TEs= Iron Bra of Death" - That is funny.

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