Ac & Taxol

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just left oncologist consult appointment. He's recommending AC & Taxol. So looking for others that have been through this regimen. He said I'd probably feel fatigued day after chemo. But that overall most due well. He downplayed the cardiac risks & allergic reaction. Said there shouldn't be much vomiting.

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  • buttaflydiva
    buttaflydiva Member Posts: 88
    edited February 2016

    ive had 2 AC and taxol treatments. I feel good day of treatment and day after. Day 3 is the worse for me, 4 and 5 are a little better and I start feeling a bit better each day. then day 7 and the following week I feel normal again. the first round my nausea meds didn't work too good and I felt pretty nauseous but never vomited. we changed out one of my meds this last time and it made a huge difference. Most of the time the meds work great, but if they don't ask your oncologist for something different. Best advice I can give you is to stay hydrated, take your nausea meds on schedule (don't wait until you feel sick to take them) and eat a little something every couple hours and you can get through it. There is fatigue, and you will probably want to rest a bit more than usual, but do make sure you get up and move around a get a little bit of exercise during these days and you will feel better. Everyone responds differently to this cocktail. Just remember the SE's are temporary and you will get through this. Good luck!

  • Kicks
    Kicks Member Posts: 4,131
    edited February 2016

    There is no way to know exactly what YOU will experience based on what 'someone else' experienced. We are each unique and there is no "One Size Fits All".

    I did 4 dD A/C neoadjuvant and 12 weekly Taxol adjuvant. For me, A/C was easy - did not slow me down at all. Taxol was not so 'nice' - I was completely and UTTERLY exhausted the entire 12 weeks but got better daily starting a week after last Taxol. For others, A/C can be 'hard' and Taxol 'easy'.

    There are many meds available that should take care of nausea. Some are given IV pre infusio, some taken oral before and after infusions for a few days. I never had any nausea even when I quit taking the oral about 1/2 way through Taxol. Emend is a very good one to take.

    There is no official research but I was told that if you had issues with morning sickness this can be a 'warning' of potential chemo nausea. I had no more ngnsickness with either son and no nausea at all with neoadjuvant and adjuvant chemo.

    As you will be doing A/C, did you talk about getting a port to protect veins? Will you be doing Neulasta to keep blood levels up? For many, it is important to start taking Claritin before Neulasta and for a while after for the pain that MAY happen - doesn't happen for all though. (Didn't for me)

    You should have a 'Chemo Education Class' - one on one - with one of the Chemo RNs before first infusion that will explain so much.

  • muska
    muska Member Posts: 1,195
    edited February 2016

    I had the treatment you were recommended in 2013. It wasn't easy but it was doable, I continued working through it and just took the days of the infusions off.

    The incidence of heart impact from AC is very very low nowadays. You can double-check but I think it's under 1%. The pre-treatment meds are so good that I never felt any nausea or had any problems with my stomach. In fact, my appetite was excellent throughout and since I didn't limit the amount of food while I was on chemo I enjoyed all kinds of foods that I wouldn't be otherwise.

    The effects of chemo are cumulative, so by the end of it you will be fatigued.

    Happy

  • cp418
    cp418 Member Posts: 7,079
    edited February 2016

    Inquire for anti-nausea medications. There is a schedule for when to take these medications to avoid vomiting. There drugs are available and they are wonderful! Write out a list for all your questions. Some doctors see so many patients they may over look communicating some information or simply assume the patient knows. Same goes for the nurses.

  • LRFTexan
    LRFTexan Member Posts: 68
    edited February 2016

    Sancuso patch is a must while going through the AC portion. I was never sick. I'm on taxol 9 tomorrow and the fatigue is starting to set in but other than that I lead a completely normal lif

  • avmom
    avmom Member Posts: 324
    edited February 2016

    I did dose dense AC followed by dose dense Taxol. I was nauseated throughout AC, but th the drugs available do help a lot. If you need to take lots of anti emetics, be sure to keep,track of the other end of your digestive tract. I found that I had to take laxatives whenever I was taking Emend or Zofran, or else things got way out of balance, which was not a good thing. After I got the hang of balancing anti emetics with laxatives, things were better.

    Not fun, but here I am, still. I even have hair now, though it is definitely a pixie cut.

  • azrescue
    azrescue Member Posts: 116
    edited February 2016

    Thank You everyone for the comments. I'm so nervous & scared. I mostly want to be able to maintain as close to normal schedule at home as possible. I think my kids need that.

  • hyphencollins
    hyphencollins Member Posts: 109
    edited February 2016

    Hi AZrescue, Wanted to chime in with thoughts of support. The regimen is doable, if unpleasant. While the A C was tough for me, I was still able to work (true, I wasn't as productive!). The weekends of my tx weren't great for family time, but fortunately it is only temporary and my young kids adapted well. My husband made extra efforts to get them out on activities those weekends. I echo what a previous poster said abt talking to your doctor abt a port, AC is ROUGH on the veins. Best wishes.

  • Houston2016
    Houston2016 Member Posts: 317
    edited May 2016

    I'm so glad for this discussion on AC+Taxol. I recently started AC four doses since April 14. I had the third dose May 19, neulasta on the 20th, I also got the steroid with my infusion. On the 20and I began to experience some chest discomfort, and nausea, shoulder and neck pain, not sure it's from the chemo, steroid, or Neulasta. I also worried about the myocardiopathy and wanted to ask my OC for changing to Taxoterra. Does any of you ladies have similar side effects?

  • mkblaylock
    mkblaylock Member Posts: 2
    edited May 2016

    I had 16 treatments. I always did them on Wednesdays. I didn't feel the effects until Friday night and over the weekend. I was able to work full time with a great company. I used the nausea meds and that helped a great deal. I also ate what I felt like eating. I was a zombie on Saturdays but by Sunday night I was ok. I also had Nuelasta the day after chemo. That also kicked in Friday night. One thing that helped me a great deal were satin pillow cases. The cotton pillow cases hurt when I laid my head down. It also kept the pillow cool. I still use them today. Amazon has them for around $8 dollars per pillow case. Best money I ever spent.

  • AnnKat
    AnnKat Member Posts: 11
    edited October 2016

    Hi everyone, I've just joined this forum. My 62 year old mom is diagnosed with Invasive Ductal Carcinoma Est+, Prog+, HER2-, between stage IIb & IIIa. She has a tumor on her breast 1.2cm and a 3.4cm tumor in the axilla that broke out of her lymph nodes. PET scan came back negative for spread. Doctor suggested treatment order chemo, surgery, radiation, and hormone therapy. My mom will have her first round of chemo this Wednesday. She will have four rounds of AC (once every 3 weeks) and 12 rounds of Taxol (once a week). I've been juicing fresh organic vegetables and fruits for my mom since her BC diagnosis a month ago. I've also been giving her immunity boosting supplements called Beta Glucan to help keep her body strong in order to deal with chemo. I want to ask if there's anyone who juice raw vegetables and fruits and or take supplements DURING chemo to help control or reduce the severity of chemo side effects? I've heard that patients undergoing chemo therapy will be very prone to infection and so I'm afraid feeding my mom raw vegetable & fruits might cause her to have infections. My mom's oncologist said it's okay for my mom to continue taking the Beta Glucan supplement during chemo because the ingredients are all natural but my mom's surgeon said she shouldn't take any supplements during chemo as it might interfere with the effectiveness with chemo treatment. I'm not sure which doctor to listen to? If there's anyone out there who know someone or personally have taken supplements and eat raw vegetables & fruits during chemo please let me know. Thank you and good luck to all who's battling this terrible disease.

  • amanda6
    amanda6 Member Posts: 121
    edited November 2016

    I am currently being treated for heart valve insufficiency ( due, my doctors suspect, from radiation to the left side) Every cardiologist I've spoken to has asked if I was given adriomycin. It is a pretty known factor in causing heart problems down the road, especially congestive heart failure.

  • mjbp
    mjbp Member Posts: 2
    edited August 2017

    I had 8 weeks of AC every other week. I had my infusions on Thursdays and was pretty much parked on the couch until the following Wednesday, but I think this was partly due to the difficulty in controlling my nausea. Zofran did not work for me (in fact, it made the nausea worse), so my onc tried compazine and even haloperidol, which also didn't work very well but obliterated my mind. Fortunately, I live in a state where medical marijuana is legal, and this did the trick -- I would recommend it as a last (and even a first) resort since it worked better than anything else with fewer side effects. But driving and working were not an option during the days I was medicating, generally days 1-6. However, I did continue to work on days 7-14, though my brain was pretty fuzzy in general by the time I got to AC #4, and I often had to nap in my office at lunchtime. The dexamethasone caused insomnia for me, so some of my brain fuzz was definitely from prolonged lack of good sleep.

    I am now almost finished with 12 weekly Taxols and have been able to maintain almost completely normal activity during this phase. No side effects at all, except for a little bit of numbness in my fingertips. It has been a piece of cake compared to the AC. I have been able to work every day except for infusion day, and that is only because they give me my infusion with 50mg of Benadryl and I am out like a light. I tend to feel tired and heart-burny on days 3 and 4, but it is completely tolerable. My taste buds came back early on in the taxol phase, and hair started growing back in earnest at about week 8. At the end of the AC phase, I thought I could not possibly go on for 3 more months, so I have been pleasantly surprised at how un-horrible the last 12 weeks have been.

  • Moderators
    Moderators Member Posts: 25,912
    edited August 2017

    Welcome, Mjbp! We're glad you've joined us and appreciate you sharing your experiences. We hope you find this community to be a source of support as you continue your treatment and beyond!

    The Mods

  • Jshelton730
    Jshelton730 Member Posts: 1
    edited June 2018

    I had 12 rounds of Taxol plus 4 rounds of herceptin and perjeta.I just had lumpectomy last week and they said my nodes are clear as well as the margins. My original plan was to have AC chemo after surgery and then radiation. I’m wondering why I would need the additional chemo ?! My appointment is tomorrow with my oncologist but I’m trying to prepare myself for her to tell me i do need it .....oh the anxiety 😓

  • moth
    moth Member Posts: 4,800
    edited June 2018

    Jshelton - chemo would be to reduce risk of recurrence.

    Your oncologist should be able to give you some numbers to indicate what the level of reduction of risk is.

    This is the nasty thing about breast cancer - you cut it out but it can come back. If it comes back in the breast, it's treatable again. If it comes back in another part of the body, that is very serious. The rads and chemo are all about preventing recurrence.

    If you put your diagnosis in your signature line, people can comment with more specific info and you can try to see who has a similar diagnosis.

    best wishes

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