Stage ll BC and adjuvent treatment with Perjeta

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forher23
forher23 Member Posts: 18
edited April 2016 in HER2+ (Positive) Breast Cancer

Hello,

my mom was diagnosed with stage ll BC (ER+, PR-, HER2+). She already had her mastectomy and will have 6 rounds of chemo and 25 rounds of radiation. The doctor will be giving her Perjeta, but from what I read about it, Perjeta is used as a neoadjuvent treatment or for metastatic BC. I do wonder if he is using it as a preventative method of treatment, but I am definitely confused as this is a fairly new drug... Has anyone had Perjeta not for metastatic BC and as an adjuvent treatment?

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  • rainnyc
    rainnyc Member Posts: 1,289
    edited April 2016

    I have. A couple of us have posted recently about this, coincidentally both at Memorial Sloan Kettering. In both cases the perjeta has been given in conjunction with Herceptin after neoadjuvant use.

    It's not a difficult drug, much easier than chemo, and since it got me to NED I cannot complain.

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  • SpecialK
    SpecialK Member Posts: 16,486
    edited April 2016

    There are a number of members on the Triple Pos thread that had adjuvant Perjeta. It is usually a matter of insurance approval since currently Perjeta for early stage breast cancer is only FDA approved for neoadjuvent use. If her insurance will approve it, it is nice to be able to have it added as it is one more tool.

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  • Mommato3
    Mommato3 Member Posts: 633
    edited April 2016

    Hi daughter, I'm one that received adjuvant Perjeta. I had my UMX right before moving out of state. There were a lot of threads that talked about how good Perjeta was so I decided to ask my new MO what she thought. She agreed that it would be good to add to my Taxol and Herceptin. She submitted it to insurance and they never questioned it. I also think it would be good to have if your insurance will pay for it.

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  • BarredOwl
    BarredOwl Member Posts: 2,433
    edited April 2016

    Here is an article noting the addition of pertuzumab (Perjeta) as an option under NCCN guidelines for breast cancer for certain patients in the adjuvant setting:

    http://www.ascopost.com/issues/may-15-2014/nccn-clinical-practice-guidelines-in-oncology-2014-updates/

    BarredOwl

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  • forher23
    forher23 Member Posts: 18
    edited April 2016

    Thank you to everyone for the reply. I definitely felt a lot better about it... and then, my mom told me she will be receiving Herceptin instead. So now, I'm looking into Herceptin. I hate that I'm so far away. It's extremely hard for me to know what's going on.

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  • forher23
    forher23 Member Posts: 18
    edited April 2016

    Hello all, just wanted to say, they took Perjeta out of her treatment plan. Not sure why... Instead, she will be using herceptin along with monotaxol and carboplatin instead.

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  • Pdrchick
    Pdrchick Member Posts: 30
    edited April 2016

    I wonder why they took out the Perjeta? I'm getting both Herceptin and Perjeta along with Taxotere and Carboplatin (TCHP). I'm non-metatastic, non-recurent and post surgery. My insurance company initially denied the perjeta, but my doc felt strongly about and and got them to approve. Best of luck to your mom!

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  • forher23
    forher23 Member Posts: 18
    edited April 2016

    hm.. I'm not sure why. I wish she was still on it as I've heard many good things. Best of luck to you as well :)

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