Her2+ but no targeted therapy

leftfootforward
leftfootforward Member Posts: 1,726
edited April 2016 in Stage IV/Metastatic Breast Cancer ONLY

Anyone out there who is Her2+ but unable to be on a targeted therapy? My heart function (EF) fell again on herceptin and so it was discontinued. I can't do TDM1 because my heart function isn't high enough yet. If my heart recovers this will be the first thing they try I think. Haven't been on it yet. Herceptin is off the table as both times I have been on it my EF has fallen to 40%. I am currently on beta blockers and an ace inhibitor. My only saving grace is that my last scan was NED so hoping that it will stay that way even without a targeted therapy. But last time I was off targeted therapy, I was diagnosed with mets in my brain and liver within 6 months.

So looking for others who aren't on targeted therapy and are doing well.

Thanks

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Comments

  • Lauriesh
    Lauriesh Member Posts: 692
    edited April 2016
    Hi left foot, I stopped herceptin because the side effects were getting too bad. I had been Ned for 4 years when I stopped in jan, 2015 and am still Ned 15 months later.
    Hopefully the heart meds will work and you can go back on.
    I have heard other women who have probems with dropping ef to take coq10 and do daily exercise to help the heart.

    Good luck
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  • MarshaMay
    MarshaMay Member Posts: 95
    edited April 2016

    Dear Left Foot, so sorry you are having heart problems. Been there and done that. My Ef went down to 10 and 5 months off H& P it was back up to 40. My onc was very anxious to get me back on H$P so she let me start at 40. That was the fall of2014 and these days I'm at about 55. NED on H&P since fall 2013. Of course in still on my cardiac meds, but that's fine with me. Maybe your cardiologist and onc could talk and find a compromise so you can stay on H& P. Good luck. Marsh

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  • Kjones13
    Kjones13 Member Posts: 1,520
    edited April 2016

    ((((leftfoot))))) no experience. Just wanted to send you a hug

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  • RonnieKay
    RonnieKay Member Posts: 2,067
    edited April 2016

    Hugs from me too! I have my echo on Friday...always that concern you're facing...that our wonder drug, herceptin, can have a devastating effect on our hearts :-( You've been one of our mighty warriors, Leftfoot, and I truly expect this to be a another battle that you will conquer! My prayers that a break will boost your heart (we know how strong it is!) and your body will stay in its NED position!!! XOXO

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