Resilient Genes

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sas-schatzi
sas-schatzi Member Posts: 19,603
edited April 2016 in Clinical Trials, Research News, Podcasts, and Study Results

This article is about a study published " online April 11 in the journal Nature Biotechnology." These researchers identified people that survived into adulthood with inherited diseases that are usually fatal in childhood. Small number of survivors--13. These survivors were gleaned from a total sample of approximately 600,000. The researchers are terming the gene that allows these folks to survive as a resilient gene. Once they find the resilient genes, the next step will be to replicate and insert the genes. Viola! fixed. The implications for all humans are tremenous

4/11/2016

Why Do Some Kids Escape Terrible Genetic Disorders by Dennis Thompson

http://health.usnews.com/health-news/articles/2016-04-11/why-do-some-kids-escape-terrible-genetic-disorders

Falls posted this http://www.reuters.com/article/us-cancer-superresponders-idUSBRE98E07420130915 . It's identifying essentially the same thing. One tough gene. We should be hearing allot about this in the next few years. :)

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  • Fallleaves
    Fallleaves Member Posts: 806
    edited April 2016

    I think my mother has some kind of resilient gene. Despite doing everything wrong (smoking, not exercising, eating junk food, staying up late, consuming a lot of sugar, etc.) she hasn't had breast cancer. Meanwhile her sister and daughter both got it, despite healthier habits. I've been thinking that, similar to the way the NCI is collecting genetic information on people who are "super responders" to breast cancer treatment (http://www.reuters.com/article/us-cancer-superresp...), we should be doing genetic sequencing on people who do everything creating risk for cancer, but don't get it. What's she got that I don't (or maybe doesn't have that I do)? Or maybe we have the same genes, but there's been DNA methylation of mine and not hers that has changed their expression.

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  • sas-schatzi
    sas-schatzi Member Posts: 19,603
    edited April 2016

    YEah, Falls..that works. I'd be mostly on the negative side.

    What'this about spreadsheets?

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  • Fallleaves
    Fallleaves Member Posts: 806
    edited April 2016

    I think you've got some of those resilient genes, too, Sas. (They may not have kept you from getting stuff, but they kept you here)

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  • sas-schatzi
    sas-schatzi Member Posts: 19,603
    edited April 2016

    Falls, didn't catch Kindles autocorrection LOL. I wrote 'superresponders' and it wrote spreadsheets. I'm looking at it this morning trying to figure out what spreadsheets were about :)

    That was a fun article. Basically, they are saying the same thing. A very tough gene. I'm going to revise the topic box and put your link there too. This is reachable within a few years. COOL!.

    I agree on the genes thingy. It makes sense, in the sense, that none of this makes sense without something like this b/c we look right and left, some are gone, some are not. We learned so much last while on Ketorolac and opiods etc, but didn't explain why some didn't recur when statistically we should have. Like me, I'm a conundrum. By everything I know I should have reoccurred early. Then around 5 years. Still never will be out of the woods. But this research fits a bit of the puzzle.

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  • Fallleaves
    Fallleaves Member Posts: 806
    edited April 2016

    Ha-ha! Yeah, I was scratching my head over the spreadsheets....

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