Pathology report
Please forgive me if this is posted on wrong forum.... feel free to move if incorrect.
Can someone help me decipher this pathology report???
Thanks in advance.
SYNOPTIC REPORT PROCEDURE: WIRE BRACKETED PARTIAL MASTECTOMY. LYMPH NODE SAMPLING: SENTINEL LYMPH NODE. SPECIMEN LATERALITY: LEFT. TUMOR SITE: UPPER OUTER QUADRANT, 2-3:00 AXIS. TUMOR SIZE: 2 X 1.8 X 1.5 CM (LARGER FOCUS OF INVASIVE CARCINOMA). HISTOLOGIC TYPE: INVASIVE DUCTAL CARCINOMA, NOS. HISTOLOGIC GRADE: GRADE 1, NOTTINGHAM SCORE 3/9 (ARCHITECTURE 1, NUCLEI 1, MITOSIS 1). TUMOR FOCALITY: TWO FOCI OF INVASIVE CARCINOMA, 1.2 CM APART. THE SMALLER FOCUS IS MORPHOLOGICALLY IDENTICAL TO THE LARGER. DUCTAL CARCINOMA IN-SITU: PRESENT, NEGATIVE FOR EXTENSIVE INTRADUCTAL COMPONENT. SIZE OF DCIS: APPROXIMATELY 8 MM. ARCHITECTURAL PATTERN OF DCIS: CRIBRIFORM. NUCLEAR GRADE DCIS: GRADE 2 (INTERMEDIATE). NECROSIS: PRESENT, COMEDO TYPE. LOBULAR CARCINOMA IN-SITU: PRESENT. MARGINS: INVASIVE CARCINOMA IS APPROXIMATELY 4 MM FROM THE ANTERIOR MARGIN AND GREATER THAN 1 CM FROM ALL OTHER MARGINS. DCIS IS 2 MM FROM THE ANTERIOR MARGIN AND GREATER THAN 1 CM FROM ALL OTHER MARGINS. LYMPH NODES: ONE SENTINEL LYMPH NODE IS EXAMINED. IT IS NEGATIVE FOR METASTASIS (PART C). LYMPH-VASCULAR INVASION: NOT IDENTIFIED. OTHER PATHOLOGIC FINDINGS: INTRADUCTAL PAPILLOMA, FIBROADENOMA, COLUMNAR CELL HYPERPLASIA, DUCT ECTASIA AND SEQUELAE OF PRIOR NEEDLE CORE BIOPSIES. TN PATHOLOGY STAGING FOR THIS SPECIMEN: pT1c, pN0 ANCILLARY STUDIES, PERFORMED ON NEEDLE CORE BIOPSY SPECIMEN (S16-1828): SITE A1: ESTROGEN RECEPTOR 100% POSITIVE, STRONG INTENSITY PROGESTERONE RECEPTOR 49% POSITIVE, MODERATE INTENSITY Ki67, PROLIFERATION MARKER 26% HIGH HER2 BY IMMUNOHISTOCHEMISTRY 2+, EQUIVOCAL HER2 BY FISH RATIO = 1.50 - NOT AMPLIFIED
Comments
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This confirms that your IDC tumor is Stage 1, Grade 1, HER2 negative, ER +, and PR+. The Ki 67 is 26% with ER at 100% and PR 49%. You also have DCIS and LCIS.
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You also have good margins, are node negative and LVI is not present - all good things. The type of IDC (what you will ultimately be treated for) is the most common among breast cancer patients,
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