Molecular subtypes of breast cancer/Luminal A & Ki 67 index

http://www.spandidos-publications.com/etm/1/5/747

hello,

I found this publication interesting. It looks at the molecular subtypes and ki-67. It makes sense because ki-67 is subjective. I have ready many posts regarding discordance between ki67 / grade and Onco score. Also, the cutoff's for Ki67 vary. Some say over 10% is high, others use 30%.

jojo - I just happened to click on this since I had responded earlier and saw your recent post - thank you for that compliment! You are sweet! How are you doing after your recent surgery?

jojo - you are in that difficult period after most active treatment is done - coping with how to feel going forward is a really common issue, and fear of recurrence when you have just come though such a process is totally normal. I was fortunate that my BS was partnering in a study with the USF School of Nursing and Moffitt Cancer Center on mindfulness based stress reduction. He steered all of his patients finishing chemo into this study if they were willing. It was a 6-week program that quantified stress reduction through before/after blood and saliva samples and included a mindfulness techniques course (a once a week class with daily meditation, relaxation and yoga and questionnaires and discussion about control, regret, habits, sleep patterns, etc.) I learned a lot about releasing past regret and how to stop worrying about a future I can't control, and truly living in the moment. It was very helpful and allowed me to calm down a bit. Due to being Her2+ I continued with Herceptin infusions beyond chemo so I also had more time to feel I was continuing to receive beneficial treatment, and that time helped me ease into looking forward. Initially I was fearful but I think two things have helped me - thanks to my participation in the MBSR study I realized I was wasting today being scared about tomorrow and it would change nothing, and I started doing everything I could to maximize my current health. Even though it may have no bearing on what happens in the future, it helps me feel proactive and that I am optimizing my situation. I joined the YMCA and participated in their Livestrong program for cancer survivors, I participated in a Her2+ recurrence prevention vaccine trial, and I changed the way I eat to control inflammation better. Whether or not any of this helps materially, it does help me to feel I am putting myself in the best possible situation. And, yes, time does help - it gets easier for most of us.