Prolia Lowers Risk of Breaking Bones in Women Taking AIs

Any one switched to Prolia because of this study? My MO just called with the results of my most recent DEXA (worse but still osteopenic) but did not recommend going on Prolia at this time. His reason seemed to be cost (I have good insurance and am confident it will be covered). If not, I've always gotten my appeals approved!

Hmmm . . . as I read the abstracts, the study looked at AIs and Prolia, are there other studies that have an arm where women were on Fosamax? Not sure it matters since I've been on Fosamax and my DEXA scores got worse. MO is not recommending change to Prolia at this time but it seems we need to do something different!

Saw my MO yesterday, he is going to request insurance approval for me to switch from Fosamax to Prolia. My bones have gotten worse since going on Arimidex a year and a half ago. Any suggestions for making it go well? Hearing about your experience with Prolia will be helpful to me!

I had my first Prolia injection a few weeks ago and much prefer it over IV Zometa infusions (I have terrible veins to start IV). I was dx with osteopenia after 2 years on Femara and if I recall had approx 8 Zometa infusions over the years. I'm really hoping Prolia will make a difference in my bone health.

cp418 - Did you have any reaction at the site or other issues?

Thanks, cp418. I appreciate that info, as I'm going to start either zometa or prolia early next year.

I hear you on the Vit. D and calcium - I never cut myself any slack on those anymore.

I start Prolia on Monday and am encouraged also with the latest results of a study that came out at the San Antonio Breast Cancer conference in December~~5 year study showing that Prolia also helps against breast cancer recurrence.

http://blog.aacr.org/sabcs-2015-denosumab-improves...

I would recommend having a DEXA scan as close to the start of Prolia as possible so that you know your density starting point.  It may take up to two years (basically 4 injections, each six months apart) before you see improvement.  For me, at the fifth injection of Prolia I was back to normal density from just osteoporotic at several measurements.  I had been osteopenic for nine years prior to diagnosis with breast cancer due to total hyst/ooph at 45, but had remained stable until chemo and six months of Femara caused serious degradation.

Had my Dexa just before the holidays and the MO wanted a "no work needed" report from dentist before starting. Unfortunately, the place where I've always done my scans has changed a equipment and said we couldn't directly compare to previous reports but the numbers had decreased from previous ones. Still osteopenic not in the osteoporosis range but I want to stay on the AI (have been on it about a year and a half). Still have to see if the insurance agrees.

Mine did the same, however his face when he saw my numbers dripped was horrifying. They stopped the Fosimax immediately as if I continue, they would turn to powder. Insurance didn't cover it the first time but after resubmitting the Prolia now they are all in.

golden the prolia didn't bother you did it? I am due for 2nd prolia in April, so far no issues, and trying yoga and prunes, calcium, and more for stronger bones too.

yes I get mine at the oncologists office. I was very worried in the beginning but now as you say " think strong bones". Nothing else.

I took 4,000 IU a day until my blood levels of Vitamin D were raised to the 60+ level. Then I cut back to 2,000 IU a day. My internist was concerned about Vitamin D levels going too high. Make sure your doctor checks your blood levels of Vitamin D. That will determine the amount you need to take.

Several years ago I was diagnosed with osteoporosis. I had been on several different drugs for my bones but all the side effects were bad and my bones weren’t getting better so we just kept changing things up. Then i went on Prolia for about 6 years (2 shots a year). A few years ago my doctor took me off of it since you should only take it for 5 years. At that time my dexa showed I was osteopenia.

Three years ago I was diagnosed with breast cancer and went through chemo and radiation. I had a dexa scan done and it showed I had osteoporosis again. After treatment my oncologist suggested I take Aremidex because I was post menopausal and my cancer was estrogen positive. Lots of side effects and osteoporosis. She had me do Zometa infusions to protect my bones. I fell back in May and broke my wrist. I have back pain that has never gone away. Nothing showed up on the X-Ray on my back so I don’t know why I am in pain. I would like to go back on Prolia since it did make my bones better and I did not have any side effects.