Angiolymphatic Invasion
I had a mastectomy December 17, 2015....just received my pathology report. One tumor removed, "angiolymphatic invasion: present (focal,D8)". Also I had 4 nodes removed, report showed: "one node positive for metastatic carcinoma". Waiting to meet Oncologist January 6th for treatment plan. Any advice or similar results for any of you?
Comments
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Pilgrim64,
Angiolymphatic invasion (also lymphovascular invasion or LVI) is present in a very large number of tumors, including those that are node negative. Although it is an independent risk factor for a node negative tumor that it is more likely to be found in either a node or to recur, your treatment staging will be based on your one positive node (among other things).
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It means that cancer cells spread to lymphatic vessels. It's not a good news, but it doesn't mean that cancer is quite advanced. More important prognostic factors are tumor size, how many lymph nodes is involved and histologic grade of malignancy. Angiolymphatic invasion occurs relatively frequent in the most common breast cancer subtypes.
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I had 19 positive nodes removed during UMX but because of location (axillary) was not considered 'metatastic' because were in 'breast area'. So Stage IIIc, not Stage IV where the cancer has spread to other areas of the body (lungs/liver/bones/etc.).
What did your Chemo Dr and Rads Dr suggest (TX Team) suggest? Surgery is only one part to the total TX plan and not always the first TX. What did your CT, MRI, bone , Pet Scans show? The node involvement? It is becoming more common to do neoadjuvant Chemo to get better surgical outcomes.
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I had LVI (my docs called it lymphovascular invasion) seen in my lymph vessels not blood vessels (though only one slide, who knows) that was "focal." I was told the "focal" was important, and that "intermediate" or "extensive" would be a lot more worrisome. My nodes were negative. I was told 4 out of 5 radiologists would say no to radiation for me, and not a single MD recommended it, but if you have one positive node that might be different.
Focus on the "focal" !!
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