What percentage ER+ and how many years NED?

Only 70% er here and just 5% pr. Uh oh!!

I had to look it up also!

95% ER+, 10% PR+

I'm a little over 6 years since diagnosis, currently NED.

100% ER+

2 years NED

100% ER, 95% PR 6 years NED

95% ER+ and maybe 30% PR+.  Not sure and I'm not looking it up.  My path report freaks me out!!

BTW- I am 10.5 years out from diagnosis.  YAY!!!!

I was 100% ER+ and 0% PR+. I'm 5 years out from diagnosis.

At my hospital they stopped reporting % ER/PR+ a few years ago. They report whether the tumor is or is not positive for ER/PR receptors based on the following stratification:

The percent of immunoreactive nuclei in the tumor cells is assessed visually and reported as follows:
- The tumor cells stain (> 10% of nuclei stained)
- Some tumor cells stain (1 to <10% of nuclei stained)
- Rare tumor cells stain (< 1% of nuclei stained)
- The tumor cells do not stain (0% of nuclei stained)

Mine was reported as:

The tumor cells stain for estrogen receptor protein.
Focally, some tumor cells stain for progesterone receptor protein.

I don't think %ER/PR+ matter much for the treatment options. For example, I would expect they put everybody who is in the first bucket (>10% of nuclei stained) on some form of hormonal treatment anyway, whether they are 15% or 99%. And we know that when progression happens, it is often a different type and the original tumor's receptor status does not matter unless it is confirmed by new biopsy.

90% ER+ and 90% PR+. I'm 3 years, 2 months out from diagnosis.

90% ER+, 30% PR+ nearly two years out..

Hi ,

E 100%, P 40%, Her2 3+

Er 100%, Pr 99.89%, 4 months NED. Also, Grade 1, Stage 1B, Oncotype Score = 3.

TectonicShift

I am 99% ER and 98%PR......from this article below it tells me that I am at high risk for late recurrence due to my high PR status......which is why I am never letting go of my Femara. I am 13 years out....but I know at any time this beast may choose to raise its ugly head. With all that I do try to not think about it too much.

Jacqueline

Discussion

We investigated factors associated with late recurrence in primary breast cancer. Risk of recurrence persisted from the first treatment to at least 20 years after treatment, and the risk is significantly increased even in patients with lymph node metastasis occurring >10 years. Regarding the biology, a reverse phenomenon was seen compared to early recurrence. The recurrence risk ≥10 years was high for the patients positive for ER and PgR, with low Ki-67 index and luminal/HER2- subtype, and negative for HER2 and p53. Multivariate analysis revealed that lymph node metastasis and PgR positivity are significant factors for late recurrence in all the tumors as well as ER-positive tumors. The recurrence rate beyond 10 years was low, and as a result the power of statistical analysis may be limited. However, the results indicated that late recurrence would occur in the PgR-positive patients with lymph node metastasis.

The full article at https://www.karger.com/Article/FullText/353099

100% ER and 100% PR, HER2 0, 5 years from dx

100 % ER - almost two years since operation..